Cyclosporine A lipid nanoparticles for oral administration: Pharmacodynamics and safety evaluation

Autor: María J. Blanco-Prieto, Melissa Guada, Maria del Carmen Dios-Viéitez, Ana Gloria Gil, Hugo Lana

Publikováno v: European Journal of Pharmaceutics and Biopharmaceutics. 101:112-118

The pharmacodynamic effect and the safety of cyclosporine A lipid nanoparticles (CsA LN) for oral administration were investigated using Sandimmune Neoral® as reference. First, the biocompatibility of the unloaded LN on Caco-2 cells was demonstrated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cde4e8ce1208ca33bd95786d92bf549
https://doi.org/10.1016/j.ejpb.2016.01.011

Lipid nanoparticles enhance the absorption of cyclosporine A through the gastrointestinal barrier: In vitro and in vivo studies

Autor: Beatriz Lasa-Saracíbar, Hugo Lana, Melissa Guada, María J. Blanco-Prieto, Maria del Carmen Dios-Viéitez

Publikováno v: International journal of pharmaceutics. 500(1-2)

In the present work, the feasibility of cyclosporine A lipid nanoparticles (CsA LN) for oral administration was investigated. Three CsA LN formulations were developed using Precirol as lipid matrix, one stabilized with Tween(®) 80 (Tw) and the other

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f22af76e7a4c699209cccb08c377cbda
https://pubmed.ncbi.nlm.nih.gov/26794875

Lipid nanoparticles for cyclosporine A administration: development, characterization, and in vitro evaluation of their immunosuppression activity

Autor: Maria del Carmen Dios-Viéitez, Victor Sebastian, María J. Blanco-Prieto, Esperanza Feijoo, Silvia Irusta, Melissa Guada

Publikováno v: Zaguán. Repositorio Digital de la Universidad de Zaragoza
instname
International Journal of Nanomedicine
Dadun. Depósito Académico Digital de la Universidad de Navarra
International Journal of Nanomedicine, Vol 2015, Iss default, Pp 6541-6553 (2015)

Melissa Guada,1,2 Victor Sebastián,3,4 Silvia Irusta,3,4 Esperanza Feijoó,1 María del Carmen Dios-Viéitez,1 María José Blanco-Prieto1,2 1Department of Pharmacy and Pharmaceutical Technology, School of Pharmacy, University of Navarra, Pamplona,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d2eb8d1421447803c86845c232cd6ee
https://www.dovepress.com/lipid-nanoparticles-for-cyclosporine-a-administration-development-char-peer-reviewed-article-IJN

Ultra high performance liquid chromatography–tandem mass spectrometry method for cyclosporine a quantification in biological samples and lipid nanosystems

Autor: Melissa Guada, María J. Blanco-Prieto, Maria del Carmen Dios-Viéitez, Hugo Lana, A. Estella-Hermoso de Mendoza, Edurne Imbuluzqueta

Publikováno v: Dadun. Depósito Académico Digital de la Universidad de Navarra
instname

Cyclosporine A (CyA) is an immunosuppressant cyclic undecapeptide used for the prevention of organ transplant rejection and in the treatment of several autoimmune disorders. An ultra high performance liquid chromatography–tandem mass spectrometry m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66b757d7480a7e0b8d584f11fa30ffa4
https://hdl.handle.net/10171/29332

Determination of fosfomycin in human urine by capillary gas chromatography: Application to clinical pharmacokinetic studies

Autor: Maria del Carmen Dios-Viéitez, M. J. Renedo, M. M. Goñi, D. Fos

Publikováno v: Scopus-Elsevier

A capillary gas chromatographic method for the determination of fosfomycin in human urine is described. After dilution of the sample and derivatization, analysis was on a HP-1 capillary column and a flame ionization detector was used to determine the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d940214f3762109aa3e5ca8b4908be0f
https://doi.org/10.1007/bf02270997