Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Maria del Carmen Arques"'
Autor:
David J. Wilkinson, Kathleen Cheung, Hua Lin, David Young, Ramsay Refaie, Maria del Carmen Arques, Sabina Janciauskiene, Andrew D. Rowan, Adrian M. D. Falconer, Helen L. Wright, Kazuhiro Yamamoto, Kenneth S. Rankin, Sarah Charlton
Publikováno v:
FEBS JOURNAL
Matrix metalloproteinase-13 (MMP-13) is a uniquely important collagenase that promotes the irreversible destruction of cartilage collagen in osteoarthritis (OA). Collagenase activation is a key control point for cartilage breakdown to occur, yet our
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4785ea187f1d88a73eb0881ed0702de
https://doi.org/10.1111/febs.16127
https://doi.org/10.1111/febs.16127
Autor:
Andrew D. Rowan, Sarah Charlton, David Young, David J. Wilkinson, Ramsay Refaie, Sabina Janciauskiene, Adrian M. D. Falconer, Kazuhiro Yamamoto, Kathleen Cheung, Hua Lin, Kenneth S. Rankin, Maria del Carmen Arques, Helen L. Wright
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e653c9c295e2396b9878f2358021fdb9
https://doi.org/10.1111/febs.16127/v2/response1
https://doi.org/10.1111/febs.16127/v2/response1
Publikováno v:
British Journal of Pharmacology. 176:38-51
Cartilage destruction is a key characteristic of arthritic disease, a process now widely established to be mediated by metzincins such as MMPs. Despite showing promise in preclinical trials during the 1990s, MMP inhibitors for the blockade of extrace
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9eb5074d63b0f2134c86218a855e2ca
https://doi.org/10.1111/bph.14173
https://doi.org/10.1111/bph.14173
Publikováno v:
British journal of pharmacology. 176(1)
Cartilage destruction is a key characteristic of arthritic disease, a process now widely established to be mediated by metzincins such as MMPs. Despite showing promise in preclinical trials during the 1990s, MMP inhibitors for the blockade of extrace
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4518cab2abd83054584b391e7d607180
https://pubmed.ncbi.nlm.nih.gov/29473950
https://pubmed.ncbi.nlm.nih.gov/29473950
Autor:
David J. Wilkinson, Yu Chen Hsu, Hua Lin, Sarah Charlton, Adrian M. D. Falconer, John C. Lockhart, Robin Plevin, Yadan Zhang, Alastair R. Hawkins, Andrew D. Rowan, Richard Leduc, Kristian Birchall, Emma Jane Blain, Antoine Désilets, Maria del Carmen Arques, William R. Ferrell, Shu-Wha Lin, Jennifer M Milner, Paul Thompson, Craig Bullock
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Increasing evidence implicates serine proteinases in the proteolytic cascades leading to the pathological destruction of extracellular matrices such as cartilage in osteoarthritis (OA). We have previously demonstrated that the type II transmembrane s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3885c854a81634af82fa264b87cc65ed
http://europepmc.org/articles/PMC5711915
http://europepmc.org/articles/PMC5711915
Autor:
Abdelhafid Bendahmane, Tracey Rayner, Maria del Carmen Arques, Catherine Chinoy, Raquel Olías, David M. Lawson, Christine Le Signor, Marion Dalmais, Alfonso Clemente, Peter Isaac, Claire Domoney
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 9, p e0138039 (2015)
PLoS ONE, Vol 10, Iss 9, p e0138039 (2015)
Several classes of seed proteins limit the utilisation of plant proteins in human and farm animal diets, while plant foods have much to offer to the sustainable intensification of food/feed production and to human health. Reduction or removal of thes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::864761fb6efdd18e208d413a21ce147f
http://europepmc.org/articles/PMC4560452
http://europepmc.org/articles/PMC4560452
Autor:
Peter Isaac, Catherine Chinoy, Alfonso Clemente, Christine Le Signor, Raquel Olías, Marion Dalmais, Tracey Rayner, Maria del Carmen Arques, Claire Domoney, David M. Lawson, Abdelhafid Bendahmane
Publikováno v:
PLoS ONE
PLoS ONE, 2015, 10 (8), ⟨10.1371/journal.pone.0134634⟩
Plos One 8 (10), . (2015)
PLoS ONE, Vol 10, Iss 8, p e0134634 (2015)
PLoS ONE, Public Library of Science, 2015, 10 (8), ⟨10.1371/journal.pone.0134634⟩
PLoS ONE, 2015, 10 (8), ⟨10.1371/journal.pone.0134634⟩
Plos One 8 (10), . (2015)
PLoS ONE, Vol 10, Iss 8, p e0134634 (2015)
PLoS ONE, Public Library of Science, 2015, 10 (8), ⟨10.1371/journal.pone.0134634⟩
International audience; Several classes of seed proteins limit the utilisation of plant proteins in human and farm animal diets, while plant foods have much to offer to the sustainable intensification of food/feed production and to human health. Redu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddf90ab9c5fc4acfef0ef46b4f596be1
https://hal.inrae.fr/hal-02633575
https://hal.inrae.fr/hal-02633575
Aberrant functioning of serine proteases in inflammatory and carcinogenic processes within the gastrointestinal tract (GIT) has prompted scientists to investigate the potential of serine protease inhibitors, both natural and synthetic, as modulators
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d00aa0344bd51a53dd30266aac550cf5
https://europepmc.org/articles/PMC4130838/
https://europepmc.org/articles/PMC4130838/
Publikováno v:
Bioactive Food Peptides in Health and Disease
Serine proteases have long been recognized as major players in a wide range of biological processes including cell signaling, cell cycle progression, digestion, immune responses, blood coagulation and wound healing. Their role in the physiology of ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afcbeb5b81d79a5712e7be9ddcc3e227
http://www.intechopen.com/articles/show/title/bowman-birk-inhibitors-from-legumes-utilisation-in-disease-prevention-and-therapy
http://www.intechopen.com/articles/show/title/bowman-birk-inhibitors-from-legumes-utilisation-in-disease-prevention-and-therapy
Autor:
Clemente A; Alfonso Clemente, Maria del Carmen Arques, Department of Physiology and Biochemistry of Nutrition, Estación Experimental del Zaidín (CSIC), 18008 Granada, Spain., Arques Mdel C; Alfonso Clemente, Maria del Carmen Arques, Department of Physiology and Biochemistry of Nutrition, Estación Experimental del Zaidín (CSIC), 18008 Granada, Spain.
Publikováno v:
World journal of gastroenterology [World J Gastroenterol] 2014 Aug 14; Vol. 20 (30), pp. 10305-15.