Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Maria dM, Vivanco"'
Autor:
Iskander Aurrekoetxea-Rodriguez, So Young Lee, Miriam Rábano, Isabel Gris-Cárdenas, Virginia Gamboa-Aldecoa, Irantzu Gorroño, Isabella Ramella-Gal, Connor Parry, Robert M. Kypta, Beñat Artetxe, Juan M. Gutierrez-Zorrilla, Maria dM. Vivanco
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Background Increased cancer stem cell (CSC) content and SOX2 overexpression are common features in the development of resistance to therapy in hormone-dependent breast cancer, which remains an important clinical challenge. SOX2 has potential
Externí odkaz:
https://doaj.org/article/e9b3f04f62bf488abdfbb2913f741c71
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Cell mechanical properties have been proposed as label free markers for diagnostic purposes in diseases such as cancer. Cancer cells show altered mechanical phenotypes compared to their healthy counterparts. Atomic Force Microscopy (AFM) is
Externí odkaz:
https://doaj.org/article/43d7274bba23475e818084d8ee1d905e
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 15, p 12208 (2023)
In healthy tissues, cells are in mechanical homeostasis. During cancer progression, this equilibrium is disrupted. Cancer cells alter their mechanical phenotype to a softer and more fluid-like one than that of healthy cells. This is connected to cyto
Externí odkaz:
https://doaj.org/article/d39f8b434b164cdca8035e2c1b58b6c1
Autor:
Erik Oliemuller, Richard Newman, Siu Man Tsang, Shane Foo, Gareth Muirhead, Farzana Noor, Syed Haider, Iskander Aurrekoetxea-Rodríguez, Maria dM Vivanco, Beatrice A Howard
Publikováno v:
eLife, Vol 9 (2020)
SOX11 is an embryonic mammary epithelial marker that is normally silenced prior to birth. High SOX11 levels in breast tumours are significantly associated with distant metastasis and poor outcome in breast cancer patients. Here, we show that SOX11 co
Externí odkaz:
https://doaj.org/article/ba0899cdda394041938c14f10c71925f
Autor:
Richard Clarkson, Julia Gee, Robert B. Clarke, Maria dM. Vivanco, Marco Piva, Fouad Alchami, Peter Barrett-Lee, Christine Morris, Philippa Young, Ladislav Andera, Iduna Fichtner, Michael Becker, Bruno M. Simões, Angelica Santiago-Gómez, Timothy Robinson, Andreia Silva, Luke Piggott
Figure S1: Endocrine-resistant MCF-7 cells demonstrate sensitivity to TRAIL Figure S2: Endocrine-resistant CSCs demonstrate sensitivity to TRIAL. Figure S3: Primary-derived patient samples. Figure S4: Endocrine-resistant primary and PDX tumour cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e19b7dfd3d8857d41b3de881fc5f24e
https://doi.org/10.1158/1078-0432.22465277
https://doi.org/10.1158/1078-0432.22465277
Autor:
Richard Clarkson, Julia Gee, Robert B. Clarke, Maria dM. Vivanco, Marco Piva, Fouad Alchami, Peter Barrett-Lee, Christine Morris, Philippa Young, Ladislav Andera, Iduna Fichtner, Michael Becker, Bruno M. Simões, Angelica Santiago-Gómez, Timothy Robinson, Andreia Silva, Luke Piggott
Purpose: One third of ER-positive breast cancer patients who initially respond to endocrine therapy become resistant to treatment. Such treatment failure is associated with poor prognosis and remains an area of unmet clinical need. Here, we identify
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7526ee6a04e59ea6737bd64b7ddcc74a
https://doi.org/10.1158/1078-0432.c.6525980
https://doi.org/10.1158/1078-0432.c.6525980
Autor:
Natalia Martín-Martín, Marco Piva, Jelena Urosevic, Paula Aldaz, James D. Sutherland, Sonia Fernández-Ruiz, Leire Arreal, Verónica Torrano, Ana R. Cortazar, Evarist Planet, Marc Guiu, Nina Radosevic-Robin, Stephane Garcia, Iratxe Macías, Fernando Salvador, Giacomo Domenici, Oscar M. Rueda, Amaia Zabala-Letona, Amaia Arruabarrena-Aristorena, Patricia Zúñiga-García, Alfredo Caro-Maldonado, Lorea Valcárcel-Jiménez, Pilar Sánchez-Mosquera, Marta Varela-Rey, Maria Luz Martínez-Chantar, Juan Anguita, Yasir H. Ibrahim, Maurizio Scaltriti, Charles H. Lawrie, Ana M. Aransay, Juan L. Iovanna, Jose Baselga, Carlos Caldas, Rosa Barrio, Violeta Serra, Maria dM Vivanco, Ander Matheu, Roger R. Gomis, Arkaitz Carracedo
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Targeting PML in acute promyelocytic leukaemia has changed the outcome of patients with this disease. Here, the authors demonstrated that PML is also a potential therapeutic target in breast cancer where it specifically regulates cancer initiating ce
Externí odkaz:
https://doaj.org/article/e6f5403164b5464bb99d566e04f080ef
Cell mechanical properties have been proposed as label free markers for diagnostic purposes in diseases such as cancer. Cancer cells show altered mechanical phenotypes compared to their healthy counterparts. Atomic Force Microscopy (AFM) is a widely
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df952362e10fb79029f58809b5680bf1
https://doi.org/10.1101/2022.12.03.518961
https://doi.org/10.1101/2022.12.03.518961
Autor:
Jagoba Iturri, Andreas Weber, Alberto Moreno-Cencerrado, Maria dM Vivanco, Rafael Benítez, Stefano Leporatti, José Luis Toca-Herrera
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 13, p 3275 (2019)
Atomic force microscopy (AFM) combined with fluorescence microscopy has been used to quantify cytomechanical modifications induced by resveratrol (at a fixed concentration of 50 µM) in a breast cancer cell line (MCF-7) upon temporal variation. Cell
Externí odkaz:
https://doaj.org/article/c671e2946af14e53ac85fd9a1e9991f4
Autor:
Rocio Ortiz, Iskander Aurrekoetxea-Rodríguez, Mathias Rommel, Iban Quintana, Maria dM Vivanco, Jose Luis Toca-Herrera
Publikováno v:
Polymers, Vol 10, Iss 12, p 1337 (2018)
New strategies in regenerative medicine include the implantation of stem cells cultured in bio-resorbable polymeric scaffolds to restore the tissue function and be absorbed by the body after wound healing. This requires the development of appropriate
Externí odkaz:
https://doaj.org/article/4620e1aacff049929c6a29b570af4ac3