Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Maria Zatsepin"'
Publikováno v:
Current Pharmaceutical Design. 26:5713-5719
Background: As not all target proteins can be easily screened in vitro, advanced virtual screening is becoming critical. Objective: In this study, we demonstrate the application of reinforcement learning guided virtual screening for γ-aminobutyric a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8258cc734bdc67c18db7032467a50803
https://doi.org/10.2174/1381612826666201113104150
https://doi.org/10.2174/1381612826666201113104150
Autor:
Immanuel Lerner, Maayan Elias, Steven G. Reed, Anke Burger-Kentischer, Andreas Kühbacher, Amit Michaeli, Maria Zatsepin, Shaul Mezan, Malcolm S. Duthie, Steffen Rupp, Doris Finkelmeier
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 201(11)
Toll-like receptor 4 plays an important role in the regulation of the innate and adaptive immune response. The majority of TLR4 activators currently in clinical use are derivatives of its prototypic ligand LPS. The discovery of innovative TLR4 activa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::207f62d90f61a34841e30b9ecd46d4d8
https://pubmed.ncbi.nlm.nih.gov/30348734
https://pubmed.ncbi.nlm.nih.gov/30348734
Autor:
Steffen Rupp, Arijit Basu, Maria Zatsepin, Angela Mattes, Amiram Goldblum, Anke Burger-Kentischer, Doris Finkelmeier
Toll-like receptors (TLR) are receptors of innate immunity that recognize pathogen associated molecular patterns. They play a critical role in many pathological states, in acute and chronic inflammatory processes. TLR9 is a promising target for drug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::265963f15f490b881aa1d2f7df629455
https://publica.fraunhofer.de/handle/publica/246599
https://publica.fraunhofer.de/handle/publica/246599
Publikováno v:
The Journal of Physical Chemistry C. 116:13827-13834
A hemin/G-quadruplex nanostructure that is immobilized on CdS quantum dots (QDs) associated with an electrode leads, in the presence of luminol, H2O2, and triethanolamine as an electron donor, to the generation of photocurrents with no external irrad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0dc17e7cfbd0fca2d85907d52fede366
https://doi.org/10.1021/jp303741x
https://doi.org/10.1021/jp303741x
Autor:
D Sean, Froese, Amit, Michaeli, Thomas J, McCorvie, Tobias, Krojer, Meitav, Sasi, Esther, Melaev, Amiram, Goldblum, Maria, Zatsepin, Alexander, Lossos, Rafael, Álvarez, Pablo V, Escribá, Berge A, Minassian, Frank, von Delft, Or, Kakhlon, Wyatt W, Yue
Publikováno v:
Human Molecular Genetics
Glycogen branching enzyme 1 (GBE1) plays an essential role in glycogen biosynthesis by generating α-1,6-glucosidic branches from α-1,4-linked glucose chains, to increase solubility of the glycogen polymer. Mutations in the GBE1 gene lead to the het
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9c9ef3acc58f6b3502d5fbf8de87f85d
https://pubmed.ncbi.nlm.nih.gov/26199317
https://pubmed.ncbi.nlm.nih.gov/26199317