Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Maria Y. Chen"'
Publikováno v:
ACS Central Science, Vol 2, Iss 10, Pp 702-709 (2016)
Externí odkaz:
https://doaj.org/article/0306b91882184a94bdcb34b5ba71f35e
Publikováno v:
Virology. 563:107-115
Adeno-associated virus (AAV) is a promising gene therapy vector, but questions remain regarding mechanisms of basic viral functions. We previously showed that a serine/threonine (S/T) triplet motif and its flanking residues, located in the overlappin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e87d25a907dc5e1f42ebf50025b419cb
https://doi.org/10.1016/j.virol.2021.08.010
https://doi.org/10.1016/j.virol.2021.08.010
Publikováno v:
ACS Synth Biol
Adeno-associated virus (AAV) vectors are currently investigated as gene transfer agents for the treatment of a variety of diseases. However, activation of the host immune response upon vector administration limits the use of AAV in the clinical setti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d7bf0bb55f3263f4483c455eb7f3790
https://doi.org/10.1021/acssynbio.0c00203
https://doi.org/10.1021/acssynbio.0c00203
Publikováno v:
ACS Synth Biol
Adeno-associated viruses (AAVs) are promising gene therapy vectors but may exhibit off-target delivery due to broad tissue tropism. We recently developed a synthetic protease-activatable AAV vector, named provector, that transduces cells preferential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf8398a42e704ca2128544dd16bb854e
https://doi.org/10.1021/acssynbio.8b00330
https://doi.org/10.1021/acssynbio.8b00330
Autor:
Nicole N. Thadani, Joanna Yang, Ciaran M. Lee, Buhle Moyo, Gang Bao, Junghae Suh, Maria Y. Chen
Publikováno v:
ACS Synth Biol
Adeno-associated virus (AAV) is widely favored as a gene therapy vector, tested in over 200 clinical trials internationally. To improve targeted delivery a variety of genetic capsid modifications, such as insertion of targeting proteins/peptides into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad469537ab6cc5ef979113aad39733c6
https://europepmc.org/articles/PMC7323921/
https://europepmc.org/articles/PMC7323921/
Autor:
A. James Link, Andrew L. Ferguson, Maria Y. Chen, Caitlin D. Allen, Dan Thanh Le, Alexander Y. Trick
Publikováno v:
ACS Chemical Biology. 11:3043-3051
Lasso peptides are a class of knot-like polypeptides in which the C-terminal tail of the peptide threads through a ring formed by an isopeptide bond between the N-terminal amine group and a side chain carboxylic acid. The small size (∼20 amino acid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ed69d36600a02cbdb1b18bd34753625
https://doi.org/10.1021/acschembio.6b00588
https://doi.org/10.1021/acschembio.6b00588
Publikováno v:
ACS Central Science
ACS Central Science, Vol 2, Iss 10, Pp 702-709 (2016)
ACS Central Science, Vol 2, Iss 10, Pp 702-709 (2016)
Lasso peptides are a member of the superclass of ribosomally synthesized and posttranslationally modified peptides (RiPPs). Like all RiPPs, lasso peptides are derived from a gene-encoded precursor protein. The biosynthesis of lasso peptides requires
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e893556cd9218d227e471ec47d8e324c
https://pubmed.ncbi.nlm.nih.gov/27800552
https://pubmed.ncbi.nlm.nih.gov/27800552