Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Maria Wohlfarth"'
Autor:
Jenny Voggel, Gregor Fink, Magdalena Zelck, Maria Wohlfarth, Julia M. Post, Laura Bindila, Manfred Rauh, Kerstin Amann, Miguel A. Alejandre Alcázar, Jörg Dötsch, Kai-Dietrich Nüsken, Eva Nüsken
Publikováno v:
Journal of Lipid Research, Vol 63, Iss 11, Pp 100283- (2022)
Intrauterine growth restriction (IUGR) predisposes to chronic kidney disease via activation of proinflammatory pathways, and omega-3 PUFAs (n-3 PUFAs) have anti-inflammatory properties. In female rats, we investigated 1) how an elevated dietary n-3/n
Externí odkaz:
https://doaj.org/article/77447104036847488c140dd450ba8acb
Autor:
Vivi F H Jensen, Anne-Marie Mølck, Jette Nowak, Maria Wohlfarth, Eva Nüsken, Damien Demozay, Kai-Dietrich Nüsken, Ingrid B Bøgh
Publikováno v:
PLoS ONE, Vol 17, Iss 3, p e0265988 (2022)
Maternal malnutrition is associated with decreased nutrient transfer to the foetus, which may lead to foetal growth restriction, predisposing children to a variety of diseases. However, regulation of placental nutrient transfer during decreased nutri
Externí odkaz:
https://doaj.org/article/9a0a516057bc45e7af4128d5a8bdcacf
Autor:
Katrin Schmitz, Eva-Maria Turnwald, Tobias Kretschmer, Ruth Janoschek, Inga Bae-Gartz, Kathrin Voßbrecher, Merlin D. Kammerer, Angela Köninger, Alexandra Gellhaus, Marion Handwerk, Maria Wohlfarth, Dirk Gründemann, Eva Hucklenbruch-Rother, Jörg Dötsch, Sarah Appel
Publikováno v:
Nutrients, Vol 14, Iss 11, p 2288 (2022)
With the gaining prevalence of obesity, related risks during pregnancy are rising. Inflammation and oxidative stress are considered key mechanisms arising in white adipose tissue (WAT) sparking obesity-associated complications and diseases. The estab
Externí odkaz:
https://doaj.org/article/0a0de6fd3df34e0ab3021f7a07044c92
Hippocampal mTOR Dysregulation and Morphological Changes in Male Rats after Fetal Growth Restriction
Autor:
Charlotte Schömig, Laura Oberholz, Gregor Fink, Jenny Voggel, Maria Wohlfarth, Jörg Dötsch, Kai-Dietrich Nüsken, Eva Nüsken
Publikováno v:
Nutrients, Vol 14, Iss 3, p 451 (2022)
Fetal growth restriction (FGR) has been linked to long-term neurocognitive impairment, especially in males. To determine possible underlying mechanisms, we examined hippocampal cellular composition and mTOR signaling of male rat FGR offspring during
Externí odkaz:
https://doaj.org/article/448abbb847224ea4942f682f62af236f
Autor:
Tobias Kretschmer, Merle Schulze-Edinghausen, Eva-Maria Turnwald, Ruth Janoschek, Inga Bae-Gartz, Peter Zentis, Marion Handwerk, Maria Wohlfarth, Astrid Schauss, Eva Hucklenbruch-Rother, Jörg Dötsch, Sarah Appel
Publikováno v:
Nutrients, Vol 12, Iss 2, p 296 (2020)
Obesity during pregnancy is a known health risk for mother and child. Since obesity is associated with increased inflammatory markers, our objectives were to determine interleukin-6 (IL-6) levels in obese mice and to examine the effect of IL-6 on pla
Externí odkaz:
https://doaj.org/article/f58dba21ad7745cba8be7837d30bab4d
Autor:
Eva Nüsken, Eva-Maria Turnwald, Gregor Fink, Jenny Voggel, Christopher Yosy, Tobias Kretschmer, Marion Handwerk, Maria Wohlfarth, Lutz T. Weber, Eva Hucklenbruch-Rother, Jörg Dötsch, Kai-Dietrich Nüsken, Sarah Appel
Publikováno v:
Journal of Clinical Medicine, Vol 8, Iss 5, p 663 (2019)
There is accumulating evidence for fetal programming of later kidney disease by maternal obesity or associated conditions. We performed a hypothesis-generating study to identify potentially underlying mechanisms. Female mice were randomly split in tw
Externí odkaz:
https://doaj.org/article/4dd49d4dc6d9487fb10fda5707ea80cb
Autor:
Gabriele Pfitzer, Jörg Dötsch, Felix Lechner, Eva Nüsken, Jenny Voggel, Maria Wohlfarth, Miguel A. Alejandre Alcazar, Gregor Fink, Kai D. Nüsken, Martin Hellmich, Kija Shah-Hosseini, Lubomir T. Lubomirov
Publikováno v:
American Journal of Physiology-Renal Physiology. 321:F93-F105
For the first time, our study presents wire myography data from renal interlobar arteries (RIAs) and mesenteric arteries of young adult rat offspring after intrauterine growth restriction (IUGR). Our data indicate that myogenic tone in RIAs is dysfun
Autor:
Elena Müller-Limberger, Isra Zayed, Eva-Maria Turnwald, Tobias Kretschmer, Ruth Janoschek, Marion Handwerk, Maria Wohlfarth, Jan-Wilm Lackmann, Stefan Müller, Eva Hucklenbruch-Rother, Sarah Appel, Jörg Dötsch
Publikováno v:
Hand in Hand zum Ziel – einfach.besser.messbar www.diabeteskongress.de.
Autor:
Tobias Kretschmer, Eva‐Maria Turnwald, Ruth Janoschek, Maria Wohlfarth, Marion Handwerk, Jörg Dötsch, Eva Hucklenbruch‐Rother, Sarah Appel
Publikováno v:
American journal of reproductive immunology (New York, N.Y. : 1989)REFERENCES. 88(1)
Pregnancy complications and adverse birth outcomes are in part fueled by the rise in obesity and its associated co-morbidities in western societies. Fetal healthy development and placental function are disturbed by an obese, inflammatory environment
Autor:
Wilhelm Bloch, Jörg Dötsch, Mojgan Ghilav, Tobias Kretschmer, Eva Hucklenbruch-Rother, Eva-Maria Turnwald, Peter Zentis, Tim van Beers, Maria Wohlfarth, Sarah Appel, Marion Handwerk, Inga Bae-Gartz, Ruth Janoschek
Publikováno v:
Biology of Reproduction. 103:1260-1274
Evidence suggests that maternal obesity (MO) can aggravate placental function causing severe pathologies during the perinatal window. However, molecular changes and mechanisms of placental dysfunction remain largely unknown. This work aimed to deciph