Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Maria Wieske"'
Autor:
Claudia Chiriches, Nathalie Nicolaisen, Maria Wieske, Heba Elhaddad, Ecmel Mehmetbeyoglu, Caroline Alvares, Dörte Becher, Paul Hole, Oliver Gerhard Ottmann, Martin Ruthardt
Publikováno v:
PLoS Genetics, Vol 18, Iss 10, p e1010463 (2022)
The WHO classifies t(6;9)-positive acute myeloid leukemia (AML) as a subgroup of high-risk AML because of its clinical and biological peculiarities, such as young age and therapy resistance. t(6;9) encodes the DEK/NUP214 fusion oncoprotein that targe
Externí odkaz:
https://doaj.org/article/b9784da331f645fe9b92d4e7d5409c3f
Autor:
Claudia Chiriches, Dilawar Khan, Maria Wieske, Nathalie Guillen, Michal Rokicki, Carol Guy, Marieangela Wilson, Kate J. Heesom, Oliver Gerhard Ottmann, Martin Ruthardt
Patients within the WHO-subgroup of t(6;9)-positive acute myeloid leukemia (AML) differ from other AML subgroups as they are characterised by younger age and a grim prognosis. Leukemic transformation can often be attributed to single chromosomal aber
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62c32fa14515f5be58a1c40634745b85
https://orca.cardiff.ac.uk/id/eprint/151862/1/Chiriches2022_Article_ActivationOfSignalingPathwaysI.pdf
https://orca.cardiff.ac.uk/id/eprint/151862/1/Chiriches2022_Article_ActivationOfSignalingPathwaysI.pdf
Autor:
Marieangela C. Wilson, Nathalie Guillen, Hannelore Held, Afsar Ali Mian, Paul S. Hole, Oliver G. Ottmann, Claudia Chiriches, Martin Ruthardt, Maria Wieske, Caroline Alvares, Dörte Becher, Andreas Otto, Carol Guy, Kate J. Heesom, Michal Jaroslaw Rokicki
SummaryAcute myeloid leukemias (AML) are characterized by recurrent genomic alterations, often in transcriptional regulators, which form the basis on which current prognostication and therapeutic intervention is overlaid. In AML transformation can of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cf55821ad18a69502c3763b2fb85382
https://doi.org/10.1101/464958
https://doi.org/10.1101/464958