Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Maria Virginia Dansey"'
Autor:
Lucía Daniela Amado, Yuliet A. Rincón, Nahuel Francisco Schenone, Emanuel Grassi, Gastón E. Siless, Gabriela Myriam Cabrera, Maria Virginia Dansey
Publikováno v:
Natural Product Research. 35:3945-3954
Five new lanostanoid triterpenes were isolated from the extract of R. microporus. Three of the metabolites (1-3) present a Δ8,9 skeleton with an uncommon keto functionality at C-1. Another compound (4) has an unprecedented rearranged skeleton in whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59b4f78874ea686205b216b11cb17c7a
https://doi.org/10.1080/14786419.2020.1752205
https://doi.org/10.1080/14786419.2020.1752205
Autor:
Adali Pecci, Maria Florencia Ogara, Maria Virginia Dansey, Gerardo Burton, Adriana S. Veleiro, Lautaro D. Alvarez, René Houtman, Carina Inés Peña
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 199
Liver X Receptors (LXRs) are ligand dependent transcription factors activated by oxidized cholesterol metabolites (oxysterols) that play fundamental roles in the transcriptional control of lipid metabolism, cholesterol transport and modulation of inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eab872712ff5a730e5972adde2e36c18
https://pubmed.ncbi.nlm.nih.gov/31931135
https://pubmed.ncbi.nlm.nih.gov/31931135
Autor:
Adali Pecci, Marta S. Maier, Diego Y. Grinman, Edith C. Kordon, Michael C. Rudolph, Elizabeth A. Wellberg, Steven M. Anderson, Valeria P. Careaga, Gerardo Burton, Maria Virginia Dansey, Paul S. MacLean
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Am J Physiol Endocrinol Metab
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Am J Physiol Endocrinol Metab
Liver X receptors (LXRs) are li-gand-dependent transcription factors activated by cholesterol metabolites. These receptors induce a suite of target genes required for de novo synthesis of triglycerides and cholesterol transport in many tissues. Two d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f8fa11d3bee672dcfce9aa8fbe0a12b
https://www.physiology.org/doi/10.1152/ajpendo.00548.2018
https://www.physiology.org/doi/10.1152/ajpendo.00548.2018
Autor:
Maria Virginia Dansey, Martin Stortz, Diego M. Presman, Gerardo Burton, Valeria Levi, Luciana Bruno, Paolo Annibale, Enrico Gratton, Adali Pecci
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Stortz, M; Presman, DM; Bruno, L; Annibale, P; Dansey, MV; Burton, G; et al.(2017). Mapping the Dynamics of the Glucocorticoid Receptor within the Nuclear Landscape. SCIENTIFIC REPORTS, 7. doi: 10.1038/s41598-017-06676-0. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/8w07p458
Scientific Reports
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Stortz, M; Presman, DM; Bruno, L; Annibale, P; Dansey, MV; Burton, G; et al.(2017). Mapping the Dynamics of the Glucocorticoid Receptor within the Nuclear Landscape. SCIENTIFIC REPORTS, 7. doi: 10.1038/s41598-017-06676-0. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/8w07p458
Scientific Reports
The distribution of the transcription machinery among different sub-nuclear domains raises the question on how the architecture of the nucleus modulates the transcriptional response. Here, we used fluorescence fluctuation analyses to quantitatively e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a1fe6b397d0d7a7133d3bf289043bf3
https://doi.org/10.1038/s41598-017-06676-0
https://doi.org/10.1038/s41598-017-06676-0
Publikováno v:
Steroids. 121
A new methodology to obtain C-25 and C-26 steroidal acids starting from pregnenolone is described. Construction of the side chain was achieved by applying the Mukaiyama aldol reaction with a non-hydrolytic work-up to isolate the trapped silyl enol et
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::564a6cab9daf4dee21ea5ad35ead9531
https://pubmed.ncbi.nlm.nih.gov/28300583
https://pubmed.ncbi.nlm.nih.gov/28300583
Autor:
Pablo H. Di Chenna, Paola Y. Bertucci, Marcelo A. Martí, Adali Pecci, Maria Virginia Dansey, Lautaro D. Alvarez, Gerardo Burton
Publikováno v:
Bioorganic & Medicinal Chemistry. 19:1683-1691
The biological activity of two seven-membered A-ring (A-homo) analogues of progesterone was evaluated by transactivation assays in Cos-1 cells and by determination of Bcl-x L expression levels in T47D cells. The results show that both compounds act a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aeb381b200c336d6b33d3dd79f0ad1be
https://doi.org/10.1016/j.bmc.2011.01.033
https://doi.org/10.1016/j.bmc.2011.01.033
Autor:
Adriana Silvia Veleiro, Pablo H. Di Chenna, Zdena Kristofikova, Maria Virginia Dansey, Hana Chodounska, Alexander Kasal, Gerardo Burton
Publikováno v:
European Journal of Medicinal Chemistry. 45:3063-3069
A procedure is described for the preparation of A-homo-5-pregnenes via an acid catalyzed rearrangement of cyclopropylcarbinols assisted by microwave irradiation. 3alpha-Hydroxy and 4alpha-hydroxy-A-homo-5-pregnen-20-one, analogues of the neuroactive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::441fc1de1d42535fb40d907570d0071f
https://doi.org/10.1016/j.ejmech.2010.03.037
https://doi.org/10.1016/j.ejmech.2010.03.037
Autor:
Adali Pecci, Lautaro D. Alvarez, Gerardo Burton, Maria Virginia Dansey, Gisela Anabel Samaja, Adriana S. Veleiro, Olga A. Castro, Daiana S. Escudero
Publikováno v:
The Biochemical journal. 465(1)
Dafachronic acids (DAs) are 3-keto cholestenoic acids bearing a carboxylic acid moiety at the end of the steroid side chain. These compounds interact with the DAF-12 receptor, a ligand-dependent transcription factor that acts as a molecular switch me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abae4c10751e27c2240b551295457477
https://pubmed.ncbi.nlm.nih.gov/25374049
https://pubmed.ncbi.nlm.nih.gov/25374049
Autor:
Gerardo Burton, Gisela Anabel Samaja, Adali Pecci, Olga A. Castro, Adriana S. Veleiro, Lautaro D. Alvarez, Daiana S. Escudero, Maria Virginia Dansey
27-Nor-Δ4-dafachronic acid was prepared in nine steps and 14% overall yield by two sequential 2-carbon homologations from 20β-carboxyaldehyde-4-pregnen-3-one. Its activity was evaluated in vivo, where it rescued the Mig phenotype of daf-9(rh50) Cae
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::329ca84d7b2235d34091a6706f3e608e
http://www.sciencedirect.com/science/article/pii/S0960894X13003995
http://www.sciencedirect.com/science/article/pii/S0960894X13003995
Autor:
Pablo H. Di Chenna, Gerardo Burton, Hana Chodounska, Adriana Silvia Veleiro, Zdena Kristofikova, Maria Virginia Dansey, Alexander Kasal
Publikováno v:
ChemInform. 41
Key steps in the synthesis of title compounds, e.g. (VIII), are a microwave-assisted rearrangement of cyclopropylcarbinol (I) and a regio- and stereospecific β-epoxidation of diene (III) in the presence of a fructose-derived ketone as chiral catalys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7205dc6438547323b2c1f63f437aeec
https://doi.org/10.1002/chin.201042190
https://doi.org/10.1002/chin.201042190