Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Maria Virginia Centeno"'
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 8 (2014)
Neuropathic pain is associated with hyperexcitability and intrinsic firing of dorsal root ganglia (DRG) neurons. These phenotypical changes can be long lasting, potentially spanning the entire life of animal models, and depend on altered expression o
Externí odkaz:
https://doaj.org/article/c9d534af78984f5a8a6f84972db41824
Autor:
Samantha Cermak, Maria Virginia Centeno, Rami Jabakhanji, Andrew Vigotsky, Julia Cox, Andrew Brink, Apkar Vania Apkarian
We studied the behavioral consequences of fentanyl vapor self-administration (SA) in mice with and without chronic neuropathic pain (one month after spared-nerve injury(SNI) model or sham injury). We assessed fentanyl consumption, motivation, and see
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f10a3fa70aeabc27b3a20fca631dc59
https://doi.org/10.1101/2022.09.22.508919
https://doi.org/10.1101/2022.09.22.508919
Autor:
Haram Kim, Zuchao Mao, Marco Martina, Yiyuan Yang, Xuhong Wei, Philipp Gutruf, Jelena Radulovic, Apkar Vania Apkarian, Daniele Procissi, Yajing Li, Maria Virginia Centeno, Wenjie Ren, D. James Surmeier, Xian-Guo Liu, Anna Maria Borruto, Rami Jabakhanji, John A. Rogers, Ting Xu
Publikováno v:
Pain
Supplemental Digital Content is Available in the Text. Pharmacological, optogenetic, and chemogenetic modulation of neuronal excitability of the dorsal, but not the ventral, hippocampus induces analgesia in rodent models of neuropathic pain.
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Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84862de22365eb78c01099fa2461d1f7
https://doi.org/10.1097/j.pain.0000000000002279
https://doi.org/10.1097/j.pain.0000000000002279
Autor:
Yi Zhang, Mariah A.A. Meyer, Marco Martina, Philipp Gutruf, Haram Kim, Yixin Wu, John A. Rogers, Dalton James Surmeier, Viktoriya S. Grayson, Can Gao, Vladimir Jovasevic, Jelena Radulovic, Wenjie Ren, Apkar Vania Apkarian, Maria Virginia Centeno, Yuan Han, Anita L. Guedea
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications
Nature Communications
The positive or negative value (valence) of past experiences is normally integrated into neuronal circuits that encode episodic memories and plays an important role in guiding behavior. Here, we show, using mouse behavioral models, that glutamatergic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27732d8ea58a6bd28733f388b7fcc64b
http://link.springer.com/article/10.1038/s41467-020-15035-z
http://link.springer.com/article/10.1038/s41467-020-15035-z
Autor:
Qi-Yuan Bao, Pei-Ching Chang, Maria Virginia Centeno, Melissa A. Farmer, Marwan Baliki, Daniel Procissi, Weibin Zhang, A. Vania Apkarian
Publikováno v:
Pain. 163(10)
Following surgical repair after peripheral nerve injury, neuropathic pain diminishes in most patients but can persist in a small proportion of cases, the mechanism of which remains poorly understood. Based on the spared nerve injury (SNI), we develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57a7f7cfa4df008c4a3cbada768e3beb
https://pubmed.ncbi.nlm.nih.gov/35082247
https://pubmed.ncbi.nlm.nih.gov/35082247
Autor:
Ian R. Wickersham, D. James Surmeier, A. Vania Apkarian, Marco Martina, Maria Virginia Centeno, Xu-Hong Wei, Wenjie Ren
Publikováno v:
Pain
The nucleus accumbens (NAc) and the ventral tegmental area (VTA) are critical hubs in the brain circuitry controlling chronic pain. Yet, how these 2 regions interact to shape the chronic pain state is poorly understood. Our studies show that in mice,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0df5022d71b36b2efdae753211746242
https://pubmed.ncbi.nlm.nih.gov/33021562
https://pubmed.ncbi.nlm.nih.gov/33021562
Autor:
A. Vania Apkarian, Alexis T. Baria, Pei-Ching Chang, Maria Virginia Centeno, Mariam E. Ghantous, Daniele Procissi
Publikováno v:
Journal of Neurophysiology. 119:834-848
Even though a number of findings, based on information content or information integration, are shown to define neural underpinnings characteristic of a conscious experience, the neurophysiological mechanism of consciousness is still poorly understood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9bea6cffbf380709b9602bff50f3d73
https://doi.org/10.1152/jn.00714.2017
https://doi.org/10.1152/jn.00714.2017
Publikováno v:
Pain. 158:488-497
Tactile allodynia, a condition in which innocuous mechanical stimuli are perceived as painful, is a common feature of chronic pain. However, how the brain reorganizes in relation to the emergence of tactile allodynia is still largely unknown. This ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::644593842c24f881db78f9dc09a7ba23
https://doi.org/10.1097/j.pain.0000000000000788
https://doi.org/10.1097/j.pain.0000000000000788
Publikováno v:
Neurosci Lett
The neuropathic pain phenotype is the consequence of functional and morphological reorganization of the PNS and CNS. This reorganization includes DRGs and the spinal cord, and extends to multiple supraspinal areas including the limbic and reward syst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1912207d0ab782aae80718280fc5f9ea
https://pubmed.ncbi.nlm.nih.gov/30503921
https://pubmed.ncbi.nlm.nih.gov/30503921
Autor:
Dalton James Surmeier, Marco Martina, Ting Xu, Daniele Procissi, Xialin Liu, Xuhong W, Jelena Radulovic, Wenjie Ren, Apkar Vania Apkarian, Maria Virginia Centeno, Rami Jabakhanji
Accumulating evidence suggests the hippocampus being involved in, and modified with, chronic neuropathic pain. However, it is still not clear whether hippocampal activity has direct control over neuropathic behaviors. Here we show that activation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cce9894d67a559cd36f9eb1ad603d503