Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Maria Veneziano"'
Autor:
Annalise Di Marco, Domenico Vignone, Odalys Gonzalez Paz, Ivan Fini, Maria Rosaria Battista, Antonella Cellucci, Elena Bracacel, Giulio Auciello, Maria Veneziano, Vinod Khetarpal, Mark Rose, Alessandro Rosa, Isabelle Gloaguen, Edith Monteagudo, Todd Herbst, Celia Dominguez, Ignacio Muñoz-Sanjuán
Publikováno v:
Cells, Vol 9, Iss 4, p 994 (2020)
The blood-brain barrier (BBB) is responsible for the homeostasis between the cerebral vasculature and the brain and it has a key role in regulating the influx and efflux of substances, in healthy and diseased states. Stem cell technology offers the o
Externí odkaz:
https://doaj.org/article/d4344a862cc142e2914339bfced09308
Autor:
Longbin Liu, Peter D. Johnson, Michael E. Prime, Vinod Khetarpal, Christopher J. Brown, Luca Anzillotti, Daniele Bertoglio, Xuemei Chen, Samuel Coe, Randall Davis, Anthony P. Dickie, Simone Esposito, Elise Gadouleau, Paul R. Giles, Catherine Greenaway, James Haber, Christer Halldin, Scott Haller, Sarah Hayes, Todd Herbst, Frank Herrmann, Manuela Heßmann, Ming Min Hsai, Yaser Khani, Adrian Kotey, Angelo Lembo, John E. Mangette, Gwendolyn A. Marriner, Richard W. Marston, Matthew R. Mills, Edith Monteagudo, Anton Forsberg-Morén, Sangram Nag, Laura Orsatti, Christine Sandiego, Sabine Schaertl, Joanne Sproston, Steven Staelens, Jack Tookey, Penelope A. Turner, Andrea Vecchi, Maria Veneziano, Ignacio Muñoz-Sanjuan, Jonathan Bard, Celia Dominguez
Publikováno v:
Journal of Medicinal Chemistry. 66:641-656
Autor:
Simone Esposito, Alain Krick, Olivier Pasquier, Fabrice Bonche, Raffaele Ingenito, Paola Magotti, Elisabetta Bianchi, Edith Monteagudo, Mariana Gallo, Daniel Oscar Cicero, Laura Orsatti, Maria Veneziano, Fulvia Caretti, Riccardo Mele, Daniela Roversi, Nadia Gennari, Denis Brasseur, Laurence Gauzy-Lazo, Olivier Duclos, Christine Mauriac, Stephane Illiano, Sergio Mallart
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis
Journal of Pharmaceutical and Biomedical Analysis, 2023, 227, pp.115256. ⟨10.1016/j.jpba.2023.115256⟩
Journal of Pharmaceutical and Biomedical Analysis, 2023, 227, pp.115256. ⟨10.1016/j.jpba.2023.115256⟩
International audience; We recently described C18 fatty acid acylated peptides as a new class of potent long-lasting single-chain RXFP1 agonists that displayed relaxin-like activities in vivo. Early pharmacokinetics and toxicological studies of these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe48f7e018f9c4ba38832ba51bf5e8f5
https://hdl.handle.net/2108/313607
https://hdl.handle.net/2108/313607
Autor:
Paola Magotti, Laura Orsatti, Sergio Mallart, Edith Monteagudo, Isabelle Menguy, Bruno Poirier, Olivier Pasquier, Elisabetta Bianchi, Hartmut Strobel, Claudius Boehm, Raffaele Ingenito, Olivier Duclos, Laurence Gauzy-Lazo, Philip Janiak, Simone Esposito, Patricia Bruneau, Federica Tucci, Maria Veneziano, Claire Minoletti, Alessia Santoprete, Alexandre Raux, Daniela Roversi, Laurence Riva, Denis Brasseur, Regine Bartsch, Alberto Bresciani, Jacques Froissant, Marie-Françoise Nicolas, Mariana Gallo, Frank Marguet, Vincent Gervat, Stéphane Illiano, Alain Corbier
Publikováno v:
Journal of Medicinal Chemistry. 64:2139-2150
The insulin-like peptide human relaxin-2 was identified as a hormone that, among other biological functions, mediates the hemodynamic changes occurring during pregnancy. Recombinant relaxin-2 (serelaxin) has shown beneficial effects in acute heart fa
Autor:
Mariana Gallo, Domitilla Vanni, Simone Esposito, Nadine Alaimo, Federica Orvieto, Federica Rulli, Antonino Missineo, Fulvia Caretti, Fabio Bonelli, Maria Veneziano, Laura Orsatti, Edith Monteagudo
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 210
Lipidation, a common strategy to improve half-life of therapeutic peptides, affects their tendency to oligomerize, their interaction with plasmatic proteins, and their catabolism. In this work, we have leveraged the use of NMR and SPR spectroscopy to
Autor:
Annalise Di Marco, Alberto Bresciani, Simona Ponzi, Antonella Cellucci, Jesus Maria Ontoria Ontoria, Alina Ciammaichella, Alessandra Francone, Steven J. Harper, Savina Malancona, Maria Veneziano, Vincenzo Summa, Edith Monteagudo, Federica Ferrigno, Emanuela Nizi, Ilaria Biancofiore, Ilaria Rossetti, Paola Pace
Publikováno v:
ACS Medicinal Chemistry Letters. 10:481-486
[Image: see text] The application of class I HDAC inhibitors as cancer therapies is well established, but more recently their development for nononcological indications has increased. We report here on the generation of improved class I selective hum
Autor:
Maria Veneziano
Publikováno v:
International Journal of Pharmacokinetics. 5
Biography: Maria Veneziano is currently a Research Investigator in the DMPK unit at IRBM (Pomezia, Italy), an Italian CRO and biotech company specializing in preclinical drug discovery of small molecules, peptides and antibodies. She studied Biologic
Autor:
Ivan Fini, Maria Veneziano, Vinod Khetarpal, Elena Bracacel, Todd Herbst, Ignacio Munoz-Sanjuan, Mark Rose, Giulio Auciello, Edith Monteagudo, Alessandro Rosa, Celia Dominguez, Odalys Gonzalez Paz, Antonella Cellucci, Annalise Di Marco, Maria Rosaria Battista, Isabelle Gloaguen, Domenico Vignone
Publikováno v:
Cells
Volume 9
Issue 4
Cells, Vol 9, Iss 994, p 994 (2020)
Volume 9
Issue 4
Cells, Vol 9, Iss 994, p 994 (2020)
The blood-brain barrier (BBB) is responsible for the homeostasis between the cerebral vasculature and the brain and it has a key role in regulating the influx and efflux of substances, in healthy and diseased states. Stem cell technology offers the o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a041cf35a29cb7bd1fddf8e63e91991e
http://hdl.handle.net/11573/1387940
http://hdl.handle.net/11573/1387940
Autor:
Adolfo Prandi, Luca Ferrante, Maria Veneziano, Mariana Gallo, Marco Ferrara, Leda Ivanova Bencheva, Antonella Cellucci, Nausicaa Mazzocchi, Pierfausto Seneci, Silvano Ronzoni, Andrea Menegon, Roberta Sinisi, Pietro Randazzo, Vincenzo Summa, Marilenia De Matteo, Romano Di Fabio
[Image: see text] Acid-sensing ion channels (ASICs) are a family of ion channels permeable to cations and largely responsible for the onset of acid-evoked ion currents both in neurons and in different types of cancer cells, thus representing a potent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c8a3bad6284485d88304e25bccd2e07
http://hdl.handle.net/11588/828238
http://hdl.handle.net/11588/828238
Autor:
Laura Orsatti, Roberto Speziale, Kathryn A. Lyons, Fulvia Caretti, Maria Vittoria Orsale, Edith Monteagudo, Maria G. Beconi, Fabio Bonelli, Maria Veneziano, Todd Herbst, Ignacio Munoz-Sanjuan, Celia Dominguez, Matteo Zini, Kelvin Chan, Leticia Toledo-Sherman
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 107:426-431
Neuroactive metabolites in the kynurenine pathway of tryptophan catabolism are associated with neurodegenerative disorders. Tryptophan is transported across the blood–brain barrier and converted via the kynurenine pathway to N-formyl- l -kynurenine