Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Maria V. Luna Velez"'
1
Akademický článek
Androgen receptor signalling confers clonogenic and migratory advantages in urothelial cell carcinoma of the bladder
Autor: Maria V. Luna‐Velez, Jelmer J. Dijkstra, Marina A. Heuschkel, Frank P. Smit, Guillaume van de Zande, Dominique Smeets, J. P. Michiel Sedelaar, Michiel Vermeulen, Gerald W. Verhaegh, Jack A. Schalken
Publikováno v: Molecular Oncology, Vol 15, Iss 7, Pp 1882-1900 (2021)
Bladder urothelial cell carcinoma (UCC) incidence is about three times higher in men compared with women. There are several indications for the involvement of hormonal factors in the aetiology of UCC. Here, we provide evidence of androgen signalling
Externí odkaz: https://doaj.org/article/232b1f170c384ea19e66163c0f81904f
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2
Akademický článek
Molecular Phenotyping of AR Signaling for Predicting Targeted Therapy in Castration Resistant Prostate Cancer
Autor: Agus Rizal A. H. Hamid, Maria V. Luna-Velez, Aleksandra M. Dudek, Cornelius F. J. Jansen, Frank Smit, Tilly W. Aalders, Gerald W. Verhaegh, Ewout Schaafsma, John P. M. Sedelaar, Jack A. Schalken
Publikováno v: Frontiers in Oncology, Vol 11 (2021)
Castration-resistant prostate cancer (CRPC) is defined by resistance of the tumor to androgen deprivation therapy (ADT). Several molecular changes, particularly in the AR signaling cascade, have been described that may explain ADT resistance. The var
Externí odkaz: https://doaj.org/article/273e898c8dbd4345a42befd9aa73c40e
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3
Akademický článek
Integrative multi‐omics analysis of intestinal organoid differentiation
Autor: Rik GH Lindeboom, Lisa van Voorthuijsen, Koen C Oost, Maria J Rodríguez‐Colman, Maria V Luna‐Velez, Cristina Furlan, Floriane Baraille, Pascal WTC Jansen, Agnès Ribeiro, Boudewijn MT Burgering, Hugo J Snippert, Michiel Vermeulen
Publikováno v: Molecular Systems Biology, Vol 14, Iss 6, Pp 1-16 (2018)
Abstract Intestinal organoids accurately recapitulate epithelial homeostasis in vivo, thereby representing a powerful in vitro system to investigate lineage specification and cellular differentiation. Here, we applied a multi‐omics framework on ste
Externí odkaz: https://doaj.org/article/8a98095e739748a999d0a70f9fe23845
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4
ONECUT2 restricts Microfold cell numbers in the small intestine; a multi-omics study
Autor: Maria V. Luna Velez, Hannah K. Neikes, Rebecca R. Snabel, Yarah Quint, Chen Qian, Aniek Martens, Gert Jan C. Veenstra, Michael R. Freeman, Simon J. van Heeringen, Michiel Vermeulen
Microfold (M) cells reside in the intestinal epithelium of Peyer’s patches. Their unique ability to take up and transport antigens from the intestinal lumen to the underlying lymphoid tissue is key in the regulation of the gut-associated immune res
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d692e65ff73fed81ad605d34ec0398e1
https://doi.org/10.1101/2022.09.01.506202
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5
Androgen receptor signalling confers clonogenic and migratory advantages in urothelial cell carcinoma of the bladder
Autor: J.P. Michiel Sedelaar, Gerald W. Verhaegh, Michiel Vermeulen, Dominique Smeets, Marina A. Heuschkel, Maria V. Luna-Velez, Jelmer J. Dijkstra, Frank Smit, Jack A. Schalken, Guillaume van de Zande
Publikováno v: Molecular Oncology, 15, 7, pp. 1882-1900
Molecular Oncology, Vol 15, Iss 7, Pp 1882-1900 (2021)
Molecular Oncology, 15, 1882-1900
Molecular Oncology
Bladder urothelial cell carcinoma (UCC) incidence is about three times higher in men compared with women. There are several indications for the involvement of hormonal factors in the aetiology of UCC. Here, we provide evidence of androgen signalling
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a234ff5fe2c0dc53800c5fa4d553996
https://hdl.handle.net/2066/237636
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6
Delivery of antisense oligonucleotides for splice-correction of androgen receptor pre-mRNA in castration-resistant prostate cancer models using cell-penetrating peptides
Autor: Maria V. Luna Velez, Omar Paulino da Silva Filho, Gerald W. Verhaegh, Onno Hooij, Najoua El Boujnouni, Roland Brock, Jack A. Schalken
Publikováno v: Prostate, 82, 6, pp. 657-665
Prostate, 82, 657-665
Contains fulltext : 248260.pdf (Publisher’s version ) (Open Access) BACKGROUND: Cell-penetrating peptides (CPPs) are a promising approach for delivering antisense oligonucleotides (AONs) as they form nanosized complexes through noncovalent interact
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a66ba774a04cbe4b6d5fde79367d779
https://repository.ubn.ru.nl/handle/2066/248260
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7
Molecular Phenotyping of AR Signaling for Predicting Targeted Therapy in Castration Resistant Prostate Cancer
Autor: Maria V. Luna-Velez, Jack A. Schalken, Frank Smit, J.P.M. Sedelaar, Agus Rizal Ardy Hariandy Hamid, Ewout Schaafsma, Aleksandra M. Dudek, Cornelius F.J. Jansen, Tilly Aalders, Gerald W. Verhaegh
Publikováno v: Frontiers in Oncology, 11
Frontiers in Oncology, Vol 11 (2021)
Frontiers in Oncology
Contains fulltext : 237678.pdf (Publisher’s version ) (Open Access) Castration-resistant prostate cancer (CRPC) is defined by resistance of the tumor to androgen deprivation therapy (ADT). Several molecular changes, particularly in the AR signaling
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc03fbe08d6088f98f5e27f593162908
http://hdl.handle.net/2066/237678
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8
Integrative multi‐omics analysis of intestinal organoid differentiation
Autor: Floriane Baraille, Koen C. Oost, Cristina Furlan, Agnès Ribeiro, Boudewijn M.T. Burgering, Michiel Vermeulen, Pascal W.T.C. Jansen, Lisa van Voorthuijsen, Rik G.H. Lindeboom, Maria J. Rodriguez-Colman, Maria V. Luna-Velez, Hugo J. Snippert
Publikováno v: Molecular Systems Biology
Molecular Systems Biology, EMBO Press, 2018, 14 (6), pp.e8227. ⟨10.15252/msb.20188227⟩
Molecular Systems Biology, 14, 6, pp. 1-16
Molecular Systems Biology, 14, 1-16
International audience; Intestinal organoids accurately recapitulate epithelial homeostasis in vivo, thereby representing a powerful in vitro system to investigate lineage specification and cellular differentiation. Here, we applied a multi-omics fra
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4216f22a9983c3ad0d302905002073f3
https://hal.sorbonne-universite.fr/hal-01840432
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9
Noncoding RNAs as Novel Biomarkers in Prostate Cancer
Autor: Jack A. Schalken, C.G. Ronnau, Maria V. Luna-Velez, Gerald W. Verhaegh
Publikováno v: BioMed Research International, Vol 2014 (2014)
BioMed Research International
Prostate cancer (PCa) is the second most common diagnosed malignant disease in men worldwide. Although serum PSA test dramatically improved the early diagnosis of PCa, it also led to an overdiagnosis and as a consequence to an overtreatment of patien
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcbd803ba420fb985088ad2a5bc571fe
https://doaj.org/article/abf0caa96b0f47b3a7355e3e35209839
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