Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Maria V. Humbert"'
Autor:
Daniela P. Lage, Patrícia A.F. Ribeiro, Daniel S. Dias, Débora V.C. Mendonça, Fernanda F. Ramos, Lívia M. Carvalho, Bethina T. Steiner, Grasiele S.V. Tavares, Vívian T. Martins, Amanda S. Machado, João A. Oliveira-da-Silva, Thaís T.O. Santos, Camila S. Freitas, Jamil S. Oliveira, Bruno M. Roatt, Ricardo A. Machado-de-Ávila, Maria V. Humbert, Myron Christodoulides, Eduardo A.F. Coelho
Publikováno v:
Vaccines, Vol 8, Iss 2, p 289 (2020)
Background: Leishmaniases are neglected diseases caused by infection with Leishmania parasites and there are no human vaccines in use routinely. The purpose of this study was to examine the immunogenicity of ChimeraT, a novel synthetic recombinant va
Externí odkaz:
https://doaj.org/article/0d348c69932349ab9c3924f3d9114030
Autor:
George Devitt, Peter B. Johnson, Niall Hanrahan, Simon I.R. Lane, Magdalena C. Vidale, Bhavwanti Sheth, Joel D. Allen, Maria V. Humbert, Cosma M. Spalluto, Rodolphe C. Hervé, Karl Staples, Jonathan J. West, Robert Forster, Nullin Divecha, Christopher J McCormick, Max Crispin, Nils Hempler, Graeme P. A. Malcolm, Sumeet Mahajan
Severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) has had a tremendous impact on humanity. Prevention of transmission by disinfection of surfaces and aerosols through a chemical-free method is highly desirable. Ultraviolet C (UVC) light is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9f4e3562060d43bdf78cf1b79314429
https://doi.org/10.1101/2023.02.03.526944
https://doi.org/10.1101/2023.02.03.526944
Autor:
Débora V.C. Mendonça, Grasiele S.V. Tavares, Isabela A.G. Pereira, João A. Oliveira-da-Silva, Fernanda F. Ramos, Daniela P. Lage, Amanda S. Machado, Lívia M. Carvalho, Thiago A.R. Reis, Ana Maria R.S. Carvalho, Flaviano M. Ottoni, Fernanda Ludolf, Camila S. Freitas, Vívian T. Martins, Miguel A. Chávez-Fumagalli, Mariana C. Duarte, Maria V. Humbert, Bruno M. Roatt, Daniel Menezes-Souza, Ricardo J. Alves, Eduardo A.F. Coelho
Visceral leishmaniasis (VL) is a neglected tropical disease found in tropical and subtropical regions in the world. The therapeutics used for the treatment against disease presents problems, mainly related to drug toxicity, route of administration, h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7077fc6be3140cdb5be61c3f1d595aeb
https://eprints.soton.ac.uk/456041/
https://eprints.soton.ac.uk/456041/
Autor:
Scott E. Guimond, Courtney J. Mycroft-West, Neha S. Gandhi, Julia A. Tree, Thuy T. Le, C. Mirella Spalluto, Maria V. Humbert, Karen R. Buttigieg, Naomi Coombes, Michael J. Elmore, Matthew Wand, Kristina Nyström, Joanna Said, Yin Xiang Setoh, Alberto A. Amarilla, Naphak Modhiran, Julian D. J. Sng, Mohit Chhabra, Paul R. Young, Daniel J. Rawle, Marcelo A. Lima, Edwin A. Yates, Richard Karlsson, Rebecca L. Miller, Yen-Hsi Chen, Ieva Bagdonaite, Zhang Yang, James Stewart, Dung Nguyen, Stephen Laidlaw, Edward Hammond, Keith Dredge, Tom M. A. Wilkinson, Daniel Watterson, Alexander A. Khromykh, Andreas Suhrbier, Miles W. Carroll, Edward Trybala, Tomas Bergström, Vito Ferro, Mark A. Skidmore, Jeremy E. Turnbull
Publikováno v:
Guimond, S E, Mycroft-West, C J, Gandhi, N S, Tree, J A, Le, T T, Spalluto, C M, Humbert, M V, Buttigieg, K R, Coombes, N, Elmore, M J, Wand, M, Nyström, K, Said, J, Setoh, Y X, Amarilla, A A, Modhiran, N, Sng, J D J, Chhabra, M, Young, P R, Rawle, D J, Lima, M A, Yates, E A, Karlsson, R, Miller, R L, Chen, Y H, Bagdonaite, I, Yang, Z, Stewart, J, Nguyen, D, Laidlaw, S, Hammond, E, Dredge, K, Wilkinson, T M A, Watterson, D, Khromykh, A A, Suhrbier, A, Carroll, M W, Trybala, E, Bergström, T, Ferro, V, Skidmore, M A & Turnbull, J E 2022, ' Synthetic Heparan Sulfate Mimetic Pixatimod (PG545) Potently Inhibits SARS-CoV-2 by Disrupting the Spike-ACE2 Interaction ', ACS Central Science, vol. 8, no. 5, pp. 527-545 . https://doi.org/10.1021/acscentsci.1c01293
Heparan sulfate (HS) is a cell surface polysaccharide recently identified as a coreceptor with the ACE2 protein for the S1 spike protein on SARS-CoV-2 virus, providing a tractable new therapeutic target. Clinically used heparins demonstrate an inhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75101ad15b8e6efcd6c5105966a122c7
https://curis.ku.dk/ws/files/342967751/520518351.pdf
https://curis.ku.dk/ws/files/342967751/520518351.pdf
Autor:
Nathalia C. Galvani, Amanda S. Machado, Daniela P. Lage, Vívian T. Martins, Daysiane de Oliveira, Camila S. Freitas, Danniele L. Vale, Bruna B. Fernandes, João A. Oliveira-da-Silva, Thiago A.R. Reis, Thaís T.O. Santos, Fernanda F. Ramos, Raquel S. Bandeira, Fernanda Ludolf, Grasiele S.V. Tavares, Nathalia S. Guimarães, Unaí Tupinambás, Miguel A. Chávez-Fumagalli, Maria V. Humbert, Denise U. Gonçalves, Myron Christodoulides, Ricardo A. Machado-de-Ávila, Eduardo A.F. Coelho
Publikováno v:
Microbial pathogenesis. 162
Serological tests used for the diagnosis of tegumentary leishmaniasis (TL) presents problems, mainly related to their variable sensitivity and/or specificity, which can be caused by low levels of antileishmanial antibodies or by presence of cross-rea
Autor:
Daniela P, Lage, Patrícia A F, Ribeiro, Daniel S, Dias, Débora V C, Mendonça, Fernanda F, Ramos, Lívia M, Carvalho, Daysiane, de Oliveira, Bethina T, Steiner, Vívian T, Martins, Luísa, Perin, Amanda S, Machado, Thaís T O, Santos, Grasiele S V, Tavares, João A, Oliveira-da-Silva, Jamil S, Oliveira, Bruno M, Roatt, Ricardo A, Machado-de-Ávila, Antônio L, Teixeira, Maria V, Humbert, Eduardo A F, Coelho, Myron, Christodoulides
Publikováno v:
NPJ Vaccines
Leishmaniases are neglected diseases caused by infection with Leishmania parasites and there are currently no prophylactic vaccines. In this study, we designed in silico a synthetic recombinant vaccine against visceral leishmaniasis (VL) called Chime