Výsledky vyhledávání - "Maria V. Guevara"

Acid exposure disrupts mucus secretion and impairs mucociliary transport in neonatal piglet airways

Autor: Veronica Schurmann, Joshua S. Dadural, Laura Bravo, Yan Shin J. Liao, Kalina R. Atanasova, Maria V. Guevara, Mariana Sponchiado, Leah R. Reznikov, Emily N. Collins, Eda Eken, Shin Ping Kuan, Kevin Vogt

Publikováno v: Am J Physiol Lung Cell Mol Physiol

Tenacious mucus produced by tracheal and bronchial submucosal glands is a defining feature of several airway diseases, including cystic fibrosis (CF). Airway acidification as a driving force of CF airway pathology has been controversial. Here we test

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13dd805c75206560ddd7d486549e3124
https://doi.org/10.1152/ajplung.00025.2020

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Airway cholinergic history modifies mucus secretion properties to subsequent cholinergic challenge in diminished chloride and bicarbonate conditions

Autor: Mark J. Hoegger, Mariana Sponchiado, Leah R. Reznikov, Emily N. Collins, Maria V. Guevara, Yan Shin J. Liao, Veronica Schurmann, Kalina R. Atanasova, Laura Bravo

Publikováno v: Experimental physiologyREFERENCES. 105(10)

New findings What is the central question of this study? What is the impact of airway cholinergic history on the properties of airway mucus secretion in a cystic fibrosis-like environment? What is the main finding and its importance? Prior cholinergi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59fecac29650eac18f7706bffa2a2132
https://pubmed.ncbi.nlm.nih.gov/32735372

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Durable Changes to Airway Mucus and Fluid Secretion Following Cholinergic Challenge

Autor: Mark J. Hoegger, Veronica Schurmann, Maria V. Guevara, Leah R. Reznikov, Laura Bravo, Kalina R. Atanasova, Emily N. Collins, Mariana Sponchiado, Yan Shin J. Liao

PurposeMucus abnormalities are central to the pathophysiology of several chronic airway diseases. Mucus secretion and clearance are regulated, in part, by cholinergic innervation. Prolonged cholinergic stimulation may contribute to mucus abnormalitie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5ce03a93f9ded122977ab57722ab4b8
https://doi.org/10.1101/2020.03.27.012575

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Long-term culturing of porcine nodose ganglia

Autor: Kalina R. Atanasova, Leah R. Reznikov, Maria V. Guevara, Emily N. Collins, Shin-Ping Kuan

Publikováno v: J Neurosci Methods

BackgroundNeuronal cell cultures are widely used in the field of neuroscience. Cell dissociation allows for the isolation of a desired cell type, yet the complexity that distinguishes the nervous system is often lost as a result. Thus, culturing neur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ae35d707faf4c5dfc8c5db84a35c3d6

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Acid exposure impairs mucus secretion and disrupts mucus transport in neonatal piglet airways

Autor: Leah R. Reznikov, Kalina R. Atanasova, Shin Ping Kuan, Emily N. Collins, Veronica Schurmann, Yan Shin J. Liao, Joshua S. Dadural, Maria V. Guevara, Kevin Vogt

Tenacious mucus produced by tracheal and bronchial submucosal glands is a defining feature of cystic fibrosis (CF). Although airway acidification occurs early in CF, whether transient acidification is sufficient to initiate mucus abnormalities is unk

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bced4d8806603e8e2760e49104d1728c
https://doi.org/10.1101/669879

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