Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Maria V. D. Soares"'
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Allogeneic Hematopoietic Stem Cell Transplantation (allo-HSCT) is the only curative therapy for many hematologic malignancies, whereby the Graft-versus-Leukemia (GVL) effect plays a pivotal role in controlling relapse. However, the success of GVL is
Externí odkaz:
https://doaj.org/article/f67351aa2b0d4ae19636d217e68c9bb7
Autor:
A. Margarida Gomes, Maria V. D. Soares, Patrícia Ribeiro, Joana Caldas, Vanda Póvoa, Leila R. Martins, Alice Melão, Ana Serra-Caetano, Aida B. de Sousa, João F. Lacerda, João T. Barata
Publikováno v:
Haematologica, Vol 99, Iss 6 (2014)
Adult B-cell acute lymphoblastic leukemia remains a major therapeutic challenge, requiring a better characterization of the molecular determinants underlying disease progression and resistance to treatment. Here, using a phospho-flow cytometry approa
Externí odkaz:
https://doaj.org/article/b37f688fffe14b2992230b6ab3847ecd
Autor:
Philippe Armand, Robert J. Soiffer, Maria V. D. Soares, Mahasweta Gooptu, João F. Lacerda, Vincent T. Ho, Corey Cutler, Jason I. Avigan, Ann E. Woolley, Jerome Ritz, Haesook T. Kim, John Koreth, Edwin P. Alyea, Joseph H. Antin, Eduardo Espada, Sarah Nikiforow, Francisco M. Marty, Edouard Forcade, Matthew P. Cheng, Rizwan Romee
Publikováno v:
Blood Adv
Clinical disease caused by BK virus reactivation is a frequent complication of allogeneic hematopoietic cell transplantation (HCT). Because of the lack of effective antiviral agents, BK virus–specific T cells are emerging as a potential therapy for
Autor:
Joanne E. Cook, Maria V. D. Soares, Jeff M. Faint, Arne N. Akbar, W. Bergler, Jean M. Fletcher, Peter C. L. Beverley, Nicholas Hammerschmitt, Fiona J. Plunkett, Malcolm H.A. Rustin, Mike Salmon, Lavina L. Belaramani, Caroline S. Verbeke
Human-virus-specific CD8+ T cells that are found during primary infection have been studied almost exclusively in the peripheral blood, and it is unclear whether these cells are regulated in the same way as those in secondary lymphoid tissue. We inve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16cd768401fc38e0795a4073d8419319
https://doi.org/10.1182/blood-2003-06-1791
https://doi.org/10.1182/blood-2003-06-1791
Autor:
C. H. Orteu, Sarah E. Jackson, Joanne E. Cook, Malcolm H.A. Rustin, Peter C. L. Beverley, Arne N. Akbar, Milica Vukmanovic-Stejic, Maria V. D. Soares, Jean M. Fletcher, Mike Salmon, John R. Reed, Graham R. Foster, Katie E. Birch
Publikováno v:
The Journal of Experimental Medicine
The extent of human memory T cell proliferation, differentiation, and telomere erosion that occurs after a single episode of immune challenge in vivo is unclear. To investigate this, we injected tuberculin purified protein derivative (PPD) into the s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d76e80dc3439e288df38f71e7056f8eb
https://ora.ox.ac.uk/objects/uuid:3023f882-5d77-4fd4-8315-32656e454d87
https://ora.ox.ac.uk/objects/uuid:3023f882-5d77-4fd4-8315-32656e454d87
Autor:
Diletta Di Mitri, Natalie E. Riddell, Richard Macaulay, Luca Battistini, Sian M. Henson, Valentina Libri, David Glyn Kipling, Arne N. Akbar, Rita I. Azevedo, Maria V. D. Soares
Publikováno v:
The Journal of Immunology. 187:2093-2100
Persistent viral infections and inflammatory syndromes induce the accumulation of T cells with characteristics of terminal differentiation or senescence. However, the mechanism that regulates the end-stage differentiation of these cells is unclear. H
Autor:
Raskit Lachmann, Florian Kern, Valentina Libri, Diletta Di Mitri, Milica Vukmanovic-Stejic, Luca Battistini, Maria V. D. Soares, Rita I. Azevedo, Kwee Yong, Stephan Fuhrmann, Arne N. Akbar, Sarah E. Jackson
Publikováno v:
Immunology. 132:326-339
P>The relative roles that ageing and lifelong cytomegalovirus (CMV) infection have in shaping naive and memory CD4+ T-cell repertoires in healthy older people is unclear. Using multiple linear regression analysis we found that age itself is a stronge
Autor:
Richard Macaulay, Maria V. D. Soares, Arne N. Akbar, Sian M. Henson, Valentina Libri, Hanspeter Pircher, Fiona J. Plunkett, Ornella Franzese, Sorena Kiani-Alikhan, Sarah E. Jackson, Stephen J. Griffiths, Rita I. Azevedo, Joanne E. Masters
Publikováno v:
Blood. 113:6619-6628
Highly differentiated CD8+CD28−CD27− T cells have short telomeres, defective telomerase activity, and reduced capacity for proliferation, indicating that they are close to replicative senescence. In addition, these cells express increased levels
Autor:
Ana E. Sousa, João T. Barata, Rita Tendeiro, Maria V. D. Soares, Rita I. Azevedo, Ana Serra-Caetano, Rui M. M. Victorino
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
© 2009 by The American Society of Hematology
The CD31(+) subset of human naive CD4(+) T cells is thought to contain the population of cells that have recently emigrated from the thymus, while their CD31(-) counterparts have been proposed to ori
The CD31(+) subset of human naive CD4(+) T cells is thought to contain the population of cells that have recently emigrated from the thymus, while their CD31(-) counterparts have been proposed to ori
Autor:
Janine Oldham, Diana L. Wallace, Marion Bérard, Joanne E. Cook, Arne N. Akbar, Peter C. L. Beverley, David F. Tough, Maria V. D. Soares
Publikováno v:
Immunology. 119:243-253
Interleukin (IL)-7 and IL-15 are cytokines implicated in homeostatic control of the peripheral CD8 T-cell pool. We compared the effects of IL-7 and IL-15 on survival and proliferation of purified human CD8+ T-cell subsets. Low concentrations of eithe