Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Maria V Zakharova"'
Autor:
Olga E. Zubareva, Adeliya R. Kharisova, Anna I. Roginskaya, Anna A. Kovalenko, Maria V. Zakharova, Alexander P. Schwarz, Denis S. Sinyak, Aleksey V. Zaitsev
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 18, p 10015 (2024)
The role of astroglial and microglial cells in the pathogenesis of epilepsy is currently under active investigation. It has been proposed that the activity of these cells may be regulated by the agonists of peroxisome proliferator-activated nuclear r
Externí odkaz:
https://doaj.org/article/b6aa66db5d3b479baf557934c229edaa
Autor:
Alexander P. Schwarz, Maria V. Zakharova, Anna A. Kovalenko, Alexandra V. Dyomina, Olga E. Zubareva, Aleksey V. Zaitsev
Publikováno v:
Biomedicines, Vol 12, Iss 5, p 1100 (2024)
Reverse transcription followed by quantitative polymerase chain reaction (RT-qPCR) is a commonly used tool for gene expression analysis. The selection of stably expressed reference genes is required for accurate normalization. The aim of this study w
Externí odkaz:
https://doaj.org/article/04b5fe29883a4f0dba7627a5ea244059
Autor:
Olga E. Zubareva, Alexandra V. Dyomina, Anna A. Kovalenko, Anna I. Roginskaya, Tigran B. Melik-Kasumov, Marina A. Korneeva, Alesya V. Chuprina, Alesya A. Zhabinskaya, Stepan A. Kolyhan, Maria V. Zakharova, Marusya O. Gryaznova, Aleksey V. Zaitsev
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 9, p 8451 (2023)
Epilepsy is a challenging brain disorder that is often difficult to treat with conventional therapies. The gut microbiota has been shown to play an important role in the development of neuropsychiatric disorders, including epilepsy. In this study, th
Externí odkaz:
https://doaj.org/article/888062f71d7543b5989418425740df52
Publikováno v:
RUDN Journal of Law, Vol 24, Iss 4, Pp 901-918 (2020)
The article investigates philosophico-theoretical issues of legal regulation of labor relations in the scientific and research sphere in connection with increasing precarization in Russia and the rest of the world. Particular emphasis is made on the
Externí odkaz:
https://doaj.org/article/e9a0be3f1eb244698813d123214aa78e
Autor:
Tatyana Y. Postnikova, Alina M. Trofimova, Maria V. Zakharova, Olga I. Nosova, Alexey R. Brazhe, Dmitry E. Korzhevskii, Alexey V. Semyanov, Aleksey V. Zaitsev
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 21, p 13461 (2022)
Data on the long-term consequences of a single episode of generalized seizures in infants are inconsistent. In this study, we examined the effects of pentylenetetrazole-induced generalized seizures in three-week-old rats. One month after the seizures
Externí odkaz:
https://doaj.org/article/cd541da47bfa46e19a720addcd7a0611
Autor:
Anna A. Kovalenko, Maria V. Zakharova, Alexander P. Schwarz, Alexandra V. Dyomina, Olga E. Zubareva, Aleksey V. Zaitsev
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 5, p 2752 (2022)
Preventing epileptogenesis in people at risk is an unmet medical need. Metabotropic glutamate receptors (mGluRs) are promising targets for such therapy. However, drugs acting on mGluRs are not used in the clinic due to limited knowledge of the involv
Externí odkaz:
https://doaj.org/article/8c3cabb78eb248d6b1559e94bf6f6b6a
Autor:
Alexandra V. Dyomina, Anna A. Kovalenko, Maria V. Zakharova, Tatiana Yu. Postnikova, Alexandra V. Griflyuk, Ilya V. Smolensky, Irina V. Antonova, Aleksey V. Zaitsev
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 1, p 497 (2022)
Metabotropic glutamate receptors (mGluRs) are expressed predominantly on neurons and glial cells and are involved in the modulation of a wide range of signal transduction cascades. Therefore, different subtypes of mGluRs are considered a promising ta
Externí odkaz:
https://doaj.org/article/4aa412eaaa684392945c43cb442c2dab
Autor:
Tatyana Y. Postnikova, Sergey L. Malkin, Maria V. Zakharova, Ilya V. Smolensky, Olga E. Zubareva, Aleksey V. Zaitsev
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 16, p 8417 (2021)
Disrupted glutamate clearance in the synaptic cleft leads to synaptic dysfunction and neurological diseases. Decreased glutamate removal from the synaptic cleft is known to cause excitotoxicity. Data on the physiological effects of increased glutamat
Externí odkaz:
https://doaj.org/article/6bcbe3ccc0ab428186860331366cd400
Autor:
Alexandra V. Dyomina, Olga E. Zubareva, Ilya V. Smolensky, Dmitry S. Vasilev, Maria V. Zakharova, Anna A. Kovalenko, Alexander P. Schwarz, Alexander M. Ischenko, Aleksey V. Zaitsev
Publikováno v:
Pharmaceuticals, Vol 13, Iss 11, p 340 (2020)
Temporal lobe epilepsy is a widespread chronic disorder that manifests as spontaneous seizures and is often characterized by refractoriness to drug treatment. Temporal lobe epilepsy can be caused by a primary brain injury; therefore, the prevention o
Externí odkaz:
https://doaj.org/article/bc5533f84cc54a2d805ef825e1c2bc54
Autor:
Aleksey V. Zaitsev, Sergey L. Malkin, Tatyana Y. Postnikova, Ilya V. Smolensky, Olga E. Zubareva, Irina V. Romanova, Maria V. Zakharova, Vladimir B. Karyakin, Vladimir Zavyalov
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 23, p 5852 (2019)
Epilepsy is a common neurological disorder. Despite the availability of a wide range of antiepileptic drugs, these are unsuccessful in preventing seizures in 20−30% of patients. Therefore, new pharmacological strategies are urgently required to con
Externí odkaz:
https://doaj.org/article/5a04ffea5eae4a859ece45428cb70809