Amerind ancestry, socioeconomic status and the genetics of type 2 diabetes in a Colombian population.

Autor: Desmond D Campbell, Maria V Parra, Constanza Duque, Natalia Gallego, Liliana Franco, Arti Tandon, Tábita Hünemeier, Cátira Bortolini, Alberto Villegas, Gabriel Bedoya, Mark I McCarthy, Alkes Price, David Reich, Andrés Ruiz-Linares

Publikováno v: PLoS ONE, Vol 7, Iss 4, p e33570 (2012)

The "thrifty genotype" hypothesis proposes that the high prevalence of type 2 diabetes (T2D) in Native Americans and admixed Latin Americans has a genetic basis and reflects an evolutionary adaptation to a past low calorie/high exercise lifestyle. Ho

Externí odkaz: https://doaj.org/article/3d46c0fb39d34e47a0d1acb47f7f8b09

Genetic variation and population structure in native Americans.

Autor: Sijia Wang, Cecil M Lewis, Mattias Jakobsson, Sohini Ramachandran, Nicolas Ray, Gabriel Bedoya, Winston Rojas, Maria V Parra, Julio A Molina, Carla Gallo, Guido Mazzotti, Giovanni Poletti, Kim Hill, Ana M Hurtado, Damian Labuda, William Klitz, Ramiro Barrantes, Maria Cátira Bortolini, Francisco M Salzano, Maria Luiza Petzl-Erler, Luiza T Tsuneto, Elena Llop, Francisco Rothhammer, Laurent Excoffier, Marcus W Feldman, Noah A Rosenberg, Andrés Ruiz-Linares

Publikováno v: PLoS Genetics, Vol 3, Iss 11, p e185 (2007)

We examined genetic diversity and population structure in the American landmass using 678 autosomal microsatellite markers genotyped in 422 individuals representing 24 Native American populations sampled from North, Central, and South America. These

Externí odkaz: https://doaj.org/article/3a511dd8a0ea4141b34f05722c6a5b4e

Contrasting patterns of nuclear and mtDNA diversity in Native American populations

Autor: Ning Ning, Yang, Stephane, Mazières, Claudio, Bravi, Nicolas, Ray, Sijia, Wang, Mari-Wyn, Burley, Gabriel, Bedoya, Winston, Rojas, Maria V, Parra, Julio A, Molina, Carla, Gallo, Giovanni, Poletti, Kim, Hill, Ana M, Hurtado, Maria L, Petzl-Erler, Luiza T, Tsuneto, William, Klitz, Ramiro, Barrantes, Elena, Llop, Francisco, Rothhammer, Damian, Labuda, Francisco M, Salzano, Maria-Cátira, Bortolini, Laurent, Excoffier, Jean Michel, Dugoujon, Andrés, Ruiz-Linares

Publikováno v: Annals of Human Genetics / Stories of Human Genetics
Annals of Human Genetics / Stories of Human Genetics, 2010, pp.74(6):525-38. ⟨10.1111/j.1469-1809.2010.00608.x⟩
Annals of Human Genetics, Vol. 74, No 6 (2010) pp. 525-38
SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP

We report an integrated analysis of nuclear (autosomal, X- and Y-chromosome) short tandem repeat (STR) data and mtDNA D-loop sequences obtained in the same set of 22 Native populations from across the Americas. A north to south gradient of decreasing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::fb5a4706728fff0e99ad79c88760398e
https://hal.archives-ouvertes.fr/hal-00565213/file/PaperIntegratedDataJuly24-CE_revised.pdf