Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Maria U. Hutchins"'
Publikováno v:
Bioconjugate Chemistry. 18:1869-1878
New thiolytically cleavable dithiobenzyl (DTB) urethane-linked conjugates of methoxypoly(ethylene glycol) (mPEG) and a model protein, lysozyme, were prepared and thoroughly characterized. In contrast to our earlier communication [Zalipsky, et al. (19
Publikováno v:
Molecular Cell. 7(6):1131-1141
Cvt19 is specifically required for the transport of resident vacuolar hydrolases that utilize the cytoplasm-to-vacuole targeting (Cvt) pathway. Autophagy (Apg) and pexophagy, processes that use the majority of the same protein components as the Cvt p
Autor:
Maria U. Hutchins, Daniel J. Klionsky
Publikováno v:
The Journal of biological chemistry. 276(23)
One challenge facing eukaryotic cells is the post-translational import of proteins into organelles. This problem is exacerbated when the proteins assemble into large complexes. Aminopeptidase I (API) is a resident hydrolase of the vacuole/lysosome in
Publikováno v:
Journal of Cell Science, 112(22), 4079-4087. COMPANY OF BIOLOGISTS LTD
Organelle biogenesis and turnover are necessary to maintain biochemical processes that are appropriate to the needs of the eukaryotic cell. Specific degradation of organelles in response to changing environmental cues is one aspect of achieving prope
Publikováno v:
The Journal of biological chemistry. 272(42)
The proton-translocating ATPase of the yeast vacuole is an enzyme complex consisting of a large peripheral membrane sector (V1) and an integral membrane sector (V0), each composed of multiple subunits. The V1 sector contains subunits that hydrolyze A
B cell repertoires in HLA-sensitized kidney transplant candidates undergoing desensitization therapy
Autor:
H. Christina Fan, John F. Beausang, Stephen R. Quake, Maria U. Hutchins, Edward A. Hutchins, Rachael Curtis, Julie M. Yabu, Rene Sit, Kshama Jirage
Publikováno v:
Journal of Translational Medicine
Background Kidney transplantation is the most effective treatment for end-stage renal disease. Sensitization refers to pre-existing antibodies against human leukocyte antigen (HLA) protein and remains a major barrier to successful transplantation. De