Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Maria Tsamou"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9551 (2024)
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and fibromyalgia (FM) are chronic syndromes of unknown etiology, accompanied by numerous symptoms affecting neurological and physical conditions. Despite frequent revisions of the diagnostic
Externí odkaz:
https://doaj.org/article/a05d3aacd2a94132b7b9dd3bd4425c0b
Autor:
Maria Tsamou, Karen Vrijens, Congrong Wang, Ellen Winckelmans, Kristof Y. Neven, Narjes Madhloum, Theo M. de Kok, Tim S. Nawrot
Publikováno v:
Epigenetics, Vol 16, Iss 4, Pp 373-388 (2021)
There is an increasing interest in microRNAs (miRNAs) as they are of utmost importance in gene regulation at the posttranscriptional level. Sex-related susceptibility for non-communicable diseases later in life could originate in early life. Until no
Externí odkaz:
https://doaj.org/article/248c897094ed4a6aaa68dfecb1ffb286
Autor:
Maria Tsamou, Tim S. Nawrot, Riccardo M. Carollo, Ann-Julie Trippas, Wouter Lefebvre, Charlotte Vanpoucke, Karen Vrijens
Publikováno v:
Environment International, Vol 142, Iss , Pp 105860- (2020)
Background: Air pollution exposure during pregnancy is an important environmental health issue. Epigenetics mediate the effects of prenatal exposure and could increase disease predisposition in later life. The oncogenic miR-17/92 cluster is involved
Externí odkaz:
https://doaj.org/article/5dc4896dc5cd4a24af99509541da7b74
Publikováno v:
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-12 (2018)
Abstract Background In the early-life environment, proper development of the placenta is essential for both fetal and maternal health. Telomere length at birth has been related to life expectancy. MicroRNAs (miRNAs) as potential epigenetic determinan
Externí odkaz:
https://doaj.org/article/d7ab867588c144d785f73a9daab31778
Autor:
Maria Tsamou, Karen Vrijens, Narjes Madhloum, Wouter Lefebvre, Charlotte Vanpoucke, Tim S Nawrot
Publikováno v:
Epigenetics, Vol 13, Iss 2, Pp 135-146 (2018)
Particulate matter (PM) exposure during in utero life may entail adverse health outcomes in later-life. Air pollution's adverse effects are known to alter gene expression profiles, which can be regulated by microRNAs (miRNAs). We investigate the pote
Externí odkaz:
https://doaj.org/article/efa81ae950dd4659af581357cb35833a
Publikováno v:
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-8 (2018)
Abstract Background HIF1α, miR-210 and its downstream targets ISCU, COX-10, RAD52 and PTEN are all part of the placental hypoxia-responsive network. Tight regulation of this network is required to prevent development of maternal–fetal complication
Externí odkaz:
https://doaj.org/article/49d608e0c333454b83e235436bfc8c96
Autor:
Ellen Winckelmans, Tim S Nawrot, Maria Tsamou, Elly Den Hond, Willy Baeyens, Jos Kleinjans, Wouter Lefebvre, Nicolas Van Larebeke, Martien Peusens, Michelle Plusquin, Hans Reynders, Greet Schoeters, Charlotte Vanpoucke, Theo M de Kok, Karen Vrijens
Publikováno v:
Environmental Health, Vol 16, Iss 1, Pp 1-15 (2017)
Abstract Background Due to their lack of repair capacity mitochondria are critical targets for environmental toxicants. We studied genes and pathways reflecting mitochondrial responses to short- and medium-term PM10 exposure. Methods Whole genome gen
Externí odkaz:
https://doaj.org/article/c46f8dcc87da44978a228c684074af7e
Mother’s Pre-pregnancy BMI and Placental Candidate miRNAs: Findings from the ENVIRONAGE Birth Cohort
Autor:
Maria Tsamou, Dries S. Martens, Ellen Winckelmans, Narjes Madhloum, Bianca Cox, Wilfried Gyselaers, Tim S. Nawrot, Karen Vrijens
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract There is increasing evidence that the predisposition for development of chronic diseases arises at the earliest times of life. In this context, maternal pre-pregnancy weight might modify fetal metabolism and the child’s predisposition to d
Externí odkaz:
https://doaj.org/article/2325c4dd638f483b9628a375f9dfbdb0
Autor:
Ellen Winckelmans, Karen Vrijens, Maria Tsamou, Bram G. Janssen, Nelly D. Saenen, Harry A. Roels, Jos Kleinjans, Wouter Lefebvre, Charlotte Vanpoucke, Theo M. de Kok, Tim S. Nawrot
Publikováno v:
Environmental Health, Vol 16, Iss 1, Pp 1-17 (2017)
Abstract Background Air pollution exposure during pregnancy has been associated with adverse birth outcomes and health problems later in life. We investigated sex-specific transcriptomic responses to gestational long- and short-term exposure to parti
Externí odkaz:
https://doaj.org/article/8fc6aae16a5e4b90b3888ef4dcb85942
Autor:
Bianca Cox, Maria Tsamou, Karen Vrijens, Kristof Y. Neven, Ellen Winckelmans, Theo M. de Kok, Michelle Plusquin, Tim S. Nawrot
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Maternal body mass index (BMI) before pregnancy is known to affect both fetal growth and later-life health of the newborn, yet the implicated molecular mechanisms remain largely unknown. As the master regulator of the fetal environment, the placenta
Externí odkaz:
https://doaj.org/article/ab87aa969b034982ae2ab84e0be7adf1