Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Maria Toro Moreno"'
Autor:
Erin A. Schroeder, Maria Toro-Moreno, Rene Raphemot, Kayla Sylvester, Isabel C. Colón, Emily R. Derbyshire
Publikováno v:
mSphere, Vol 9, Iss 3 (2024)
ABSTRACTThe apicomplexans Toxoplasma gondii and Plasmodium are intracellular parasites that reside within a host-derived compartment termed the parasitophorous vacuole (PV). During infection, the parasites must acquire critical host resources and tra
Externí odkaz:
https://doaj.org/article/050246e423d74f19ae46c9a663525d47
Autor:
Sangsu Bang, Christopher R. Donnelly, Xin Luo, Maria Toro-Moreno, Xueshu Tao, Zilong Wang, Sharat Chandra, Andrey V. Bortsov, Emily R. Derbyshire, Ru-Rong Ji
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
GPR37 is expressed in macrophages, and has been implicated in resolution of inflammatory pain. Here the authors show that GPR37 can modulate sepsis in several animal models.
Externí odkaz:
https://doaj.org/article/eb825ea936f54c5198d6ef87a574a599
Publikováno v:
mBio, Vol 11, Iss 1 (2020)
ABSTRACT The apicomplexan parasites Plasmodium spp. are the causative agents of malaria, a disease that poses a significant global health burden. Plasmodium spp. initiate infection of the human host by transforming and replicating within hepatocytes.
Externí odkaz:
https://doaj.org/article/453cc204e3344120afb0e2bde561d652
Autor:
Sina Rütschlin, Ashmita Pandey, Emily R. Derbyshire, Jack G. Ganley, Kayla Sylvester, Jiannong Xu, Thomas Böttcher, Cody Champion, James M. Bradford, Maria Toro Moreno, Kuan-Yi Lu
Advances in infectious disease control strategies through genetic manipulation of insect microbiomes have heightened interest in microbially produced small molecules within mosquitoes. Herein, 33 mosquito-associated bacterial genomes were mined and o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::def52e05ea981c4d70e8669c53358d19
https://doi.org/10.1101/2020.04.09.034280
https://doi.org/10.1101/2020.04.09.034280
Autor:
Maria Toro-Moreno, Emily R. Derbyshire
Publikováno v:
Cell Chemical Biology
Summary We report detailed susceptibility profiling of asexual blood stages of the malaria parasite Plasmodium falciparum to clinical and experimental antimalarials, combined with metabolomic fingerprinting. Results revealed a variety of stage-specif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03e40429b9b0688dc28d768dab7549b0
https://pubmed.ncbi.nlm.nih.gov/31813848
https://pubmed.ncbi.nlm.nih.gov/31813848
Publikováno v:
mBio, Vol 11, Iss 1 (2020)
mBio, Vol 11, Iss 1, p e03234-19 (2020)
mBio, Vol 11, Iss 1, p e03234-19 (2020)
The apicomplexan parasitesPlasmodiumspp. are the causative agents of malaria, a disease that poses a significant global health burden.Plasmodiumspp. initiate infection of the human host by transforming and replicating within hepatocytes. This liver s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47a1dc5f1ef56954f1e0753ad71d9993
https://doi.org/10.1101/870030
https://doi.org/10.1101/870030
Publikováno v:
Biochemistry. 57(4)
Apicomplexan parasites encompass a diverse group of eukaryotic intracellular pathogens that infect various animal hosts to cause disease. Intriguingly, apicomplexans possess a unique organelle of algal origin, the apicoplast, which phylogenetically l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d7fff5904cadb34428f59fbdee78b0d
https://pubmed.ncbi.nlm.nih.gov/28976181
https://pubmed.ncbi.nlm.nih.gov/28976181
Publikováno v:
Cell Chem Biol
Summary Plasmodium parasites undergo an obligatory and asymptomatic developmental stage within the liver before infecting red blood cells to cause malaria. The hijacked host pathways critical to parasite infection during this hepatic phase remain poo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3f07d5810d8e279dfbd5fa32a7b514a
https://doi.org/10.1016/j.chembiol.2019.05.011
https://doi.org/10.1016/j.chembiol.2019.05.011
Autor:
Amber L. Eubanks, Emily R. Derbyshire, Kuan-Yi Lu, Philip F. Hughes, Rene Raphemot, Rechel Anne Geiger, Maria Toro-Moreno, Timothy A.J. Haystead
Publikováno v:
Cell Chemical Biology. 26:411-419.e7
Summary There is a scarcity of pharmacological tools to interrogate protein kinase function in Plasmodium parasites, the causative agent of malaria. Among Plasmodium's protein kinases, those characterized as atypical represent attractive drug targets
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a9d5346d75873f66f512ac0c33c19a0
https://doi.org/10.1016/j.chembiol.2018.11.003
https://doi.org/10.1016/j.chembiol.2018.11.003