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pro vyhledávání: '"Maria Thorstensson"'
Autor:
Annika Åstrand, Monika Sundqvist, Maria Thorstensson, Tomas Fex, Andreas Nordin, Ahlke Hayen, Annika Björe, Ulrik Gran, Christina Olsson, Johan Sundell, Elin Forsström, Emma Lindhardt, Jonas Boström, Gunilla Linhardt, Teresa Collins, Boel Löfberg, Fanyi Jiang, Roine I. Olsson, Ingemar Jacobson, Anna Öhrn, Karolina Aplander, Olle Hidestål, Jonna Gyll
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 23:706-710
Diphenylphosphinic amides and diphenylphosphine oxides have been synthesized and tested as inhibitors of the Kv1.5 potassium ion channel as a possible treatment for atrial fibrillation. In vitro structure-activity relationships are discussed and seve