Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Maria Teresa Pallotta"'
Autor:
Chiara Suvieri, Giada Mondanelli, Ciriana Orabona, Maria Teresa Pallotta, Eleonora Panfili, Sofia Rossini, Claudia Volpi, Maria Laura Belladonna
Publikováno v:
Cells, Vol 13, Iss 13, p 1088 (2024)
Small synthetic oligodeoxynucleotides (ODNs) can mimic microbial nucleic acids by interacting with receptor systems and promoting immunostimulatory activities. Nevertheless, some ODNs can act differently on the plasmacytoid dendritic cell (pDC) subse
Externí odkaz:
https://doaj.org/article/b6473a38dbfe41bb8541f5b56f793bc6
Autor:
Sofia Rossini, Sara Ambrosino, Claudia Volpi, Maria Laura Belladonna, Maria Teresa Pallotta, Eleonora Panfili, Chiara Suvieri, Antonio Macchiarulo, Giada Mondanelli, Ciriana Orabona
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The tryptophan-degrading enzyme indoleamine 2,3-dioxygenase 1 (IDO1) is a plastic immune checkpoint molecule that potently orchestrates immune responses within the tumor microenvironment (TME). As a heme-containing protein, IDO1 catalyzes the convers
Externí odkaz:
https://doaj.org/article/b8dc0edb91ed44c78d0c3beec312b71a
Publikováno v:
Frontiers in Clinical Diabetes and Healthcare, Vol 4 (2023)
WFS1 spectrum disorder (WFS1-SD) is a rare monogenic neurodegenerative disorder whose cardinal symptoms are childhood-onset diabetes mellitus, optic atrophy, deafness, diabetes insipidus, and neurological signs ranging from mild to severe. The progno
Externí odkaz:
https://doaj.org/article/ef348fed53b94b11abcbe1893dbcce3e
Autor:
Eleonora Panfili, Giada Mondanelli, Ciriana Orabona, Marco Gargaro, Claudia Volpi, Maria Laura Belladonna, Sofia Rossini, Chiara Suvieri, Maria Teresa Pallotta
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Indoleamine 2,3-dioxygenase 1 (IDO1) is a tryptophan metabolizing enzyme chronically activated in many cancer patients and its expression and activity correlate with a poor prognosis. In fact, it acts as an immune regulator and contributes to tumor-i
Externí odkaz:
https://doaj.org/article/5d9c941eee80447690a5ab54243d33da
Autor:
Chiara Suvieri, Francesca De Marchis, Martina Mandarano, Sara Ambrosino, Sofia Rossini, Giada Mondanelli, Marco Gargaro, Eleonora Panfili, Ciriana Orabona, Maria Teresa Pallotta, Maria Laura Belladonna, Claudia Volpi
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 22, p 16236 (2023)
Indoleamine 2,3-dioxygenase 2 (IDO2) is a paralog of Indoleamine 2,3-dioxygenase 1 (IDO1), a tryptophan-degrading enzyme producing immunomodulatory molecules. However, the two proteins are unlikely to carry out the same functions. IDO2 shows little o
Externí odkaz:
https://doaj.org/article/8d143ddeba38471d9f66a514a2767189
Autor:
Elisa Maricchiolo, Eleonora Panfili, Andrea Pompa, Francesca De Marchis, Michele Bellucci, Maria Teresa Pallotta
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
In eukaryotes, many proteins contain an N-terminal signal peptide that allows their translocation into the endoplasmic reticulum followed by secretion outside the cell according to the classical secretory system. However, an increasing number of secr
Externí odkaz:
https://doaj.org/article/f1bf6e697b174047bf19d91c290a604c
Autor:
Giorgia Manni, Sandra Buratta, Maria Teresa Pallotta, Davide Chiasserini, Alessandro Di Michele, Carla Emiliani, Stefano Giovagnoli, Luisa Pascucci, Rita Romani, Ilaria Bellezza, Lorena Urbanelli, Francesca Fallarino
Publikováno v:
Cells, Vol 12, Iss 4, p 527 (2023)
Extracellular vesicles (EVs) are membrane-enclosed particles secreted by cells and circulating in body fluids. Initially considered as a tool to dispose of unnecessary material, they are now considered an additional method to transmit cell signals. A
Externí odkaz:
https://doaj.org/article/3a3e4bc4b1d149e4a2f0815e0d9bd013
Autor:
Sonia Bianchini, Ciriana Orabona, Barbara Camilloni, Maria Giulia Berioli, Alberto Argentiero, Davide Matino, Anna Alunno, Elisa Albini, Carmine Vacca, Maria Teresa Pallotta, Giulia Mancini, Giorgia Tascini, Giada Toni, Giada Mondanelli, Ettore Silvestri, Ursula Grohmann, Susanna Esposito
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 16, Iss 1, Pp 86-94 (2020)
This study was planned to evaluate whether a 3-month treatment with Lactobacillus rhamnosus GG (LGG) can modify immune system functions in children and adolescents with type 1 diabetes (T1D), leading to an increased immune response to an injectable q
Externí odkaz:
https://doaj.org/article/829570c5e15849b182a855397f4da2c4
Autor:
Giada Mondanelli, Elisa Albini, Elena Orecchini, Maria Teresa Pallotta, Maria Laura Belladonna, Giovanni Ricci, Ursula Grohmann, Ciriana Orabona
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Obesity is a metabolic disease characterized by a state of chronic, low-grade inflammation and dominated by pro-inflammatory cytokines such as IL-6. Indoleamine 2,3-dioxygenase 1 (IDO1) is an enzyme that catalyzes the first step in the kynurenine pat
Externí odkaz:
https://doaj.org/article/bad4e1023c80414698d93ee1e952fa11
Autor:
Maria Teresa Pallotta, Giorgia Tascini, Roberta Crispoldi, Ciriana Orabona, Giada Mondanelli, Ursula Grohmann, Susanna Esposito
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-12 (2019)
Abstract Background Wolfram syndrome (WS), a rare genetic disorder, is considered the best prototype of endoplasmic reticulum (ER) diseases. Classical WS features are childhood-onset diabetes mellitus, optic atrophy, deafness, diabetes insipidus, neu
Externí odkaz:
https://doaj.org/article/41f853bb2798446893a71773b1505642