Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Maria Teresa Majorini"'
Autor:
Federica Cossu, Simone Camelliti, Daniele Lecis, Luca Sorrentino, Maria Teresa Majorini, Mario Milani, Eloise Mastrangelo
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 6366-6374 (2021)
Inhibitors of apoptosis proteins (IAPs) are validated onco-targets, as their overexpression correlates with cancer onset, progression, diffusion and chemoresistance. IAPs regulate cell death survival pathways, inflammation, and immunity. Targeting IA
Externí odkaz:
https://doaj.org/article/c86117b4d2eb46419e5f2244e91de453
Autor:
Francesca Andriani, Maria Teresa Majorini, Miguel Mano, Elena Landoni, Rosalba Miceli, Federica Facchinetti, Mavis Mensah, Enrico Fontanella, Matteo Dugo, Mauro Giacca, Ugo Pastorino, Gabriella Sozzi, Domenico Delia, Luca Roz, Daniele Lecis
Publikováno v:
Journal of Hematology & Oncology, Vol 11, Iss 1, Pp 1-17 (2018)
Abstract Background Fibroblasts are crucial mediators of tumor-stroma cross-talk through synthesis and remodeling of the extracellular matrix and production of multiple soluble factors. Nonetheless, little is still known about specific determinants o
Externí odkaz:
https://doaj.org/article/129bb9357c5543c1a5ce2d32753e0fd9
Autor:
Daniele Lecis, Mario P. Colombo, Claudio Tripodo, Claudia Chiodoni, Elda Tagliabue, Elena Jachetti, Enrico Fontanella, Loris De Cecco, Tiziana Triulzi, Matteo Dugo, Laura Botti, Alice Rigoni, Valeria Cancila, Maria Teresa Majorini
Heatmap showing genes belonging to the leading edge lists of at least four gene sets of Figure 6F. Leading edge genes drives the significance of the gene sets. The color scale of the heatmap represents the fold change of the gene in the comparison of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::196c9db5744167c75da1ef9a41845e1c
https://doi.org/10.1158/0008-5472.22423268.v1
https://doi.org/10.1158/0008-5472.22423268.v1
Autor:
Daniele Lecis, Mario P. Colombo, Claudio Tripodo, Claudia Chiodoni, Elda Tagliabue, Elena Jachetti, Enrico Fontanella, Loris De Cecco, Tiziana Triulzi, Matteo Dugo, Laura Botti, Alice Rigoni, Valeria Cancila, Maria Teresa Majorini
Supplementary Table S1. Genes differentially expressed (FDR < 0.05) between PyMT B6 and PyMT Wsh mice.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2920936150c30d775b406ea15dc62db7
https://doi.org/10.1158/0008-5472.22423262.v1
https://doi.org/10.1158/0008-5472.22423262.v1
Autor:
Daniele Lecis, Mario P. Colombo, Claudio Tripodo, Claudia Chiodoni, Elda Tagliabue, Elena Jachetti, Enrico Fontanella, Loris De Cecco, Tiziana Triulzi, Matteo Dugo, Laura Botti, Alice Rigoni, Valeria Cancila, Maria Teresa Majorini
Tumor growth and development is determined by both cancer cell–autonomous and microenvironmental mechanisms, including the contribution of infiltrating immune cells. Because the role of mast cells (MC) in this process is poorly characterized and ev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::817741ff9cd9a95e407f8947f9f3df97
https://doi.org/10.1158/0008-5472.c.6511454.v1
https://doi.org/10.1158/0008-5472.c.6511454.v1
Autor:
Maria Teresa Majorini, Mario Milani, Eloise Mastrangelo, Federica Cossu, Simone Camelliti, Luca Sorrentino, Daniele Lecis
Publikováno v:
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 6366-6374 (2021)
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 6366-6374 (2021)
Graphical abstract
Highlights • Virtual docking vs type I BIRs of IAPs identified FC2 as a modulator of NF-kB. • FC2 is active as a single agent with no toxicity in normal cells. • The cytotoxic activity of FC2 is enhanced by TNF and by th
Highlights • Virtual docking vs type I BIRs of IAPs identified FC2 as a modulator of NF-kB. • FC2 is active as a single agent with no toxicity in normal cells. • The cytotoxic activity of FC2 is enhanced by TNF and by th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c6b25bf13118244ef9827f45d20e43b
https://doi.org/10.1016/j.csbj.2021.11.034
https://doi.org/10.1016/j.csbj.2021.11.034
Publikováno v:
Cancer research. 82(8)
Tumor outcome is determined not only by cancer cell–intrinsic features but also by the interaction between cancer cells and their microenvironment. There is great interest in tumor-infiltrating immune cells, yet mast cells have been less studied. R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa518781ea367ddb08c6e49fc99736a4
https://pubmed.ncbi.nlm.nih.gov/35045983
https://pubmed.ncbi.nlm.nih.gov/35045983
Autor:
Laura Botti, Maria Teresa Majorini, Claudio Tripodo, Alice Rigoni, Mario P. Colombo, Valeria Cancila, Claudia Chiodoni, Loris De Cecco, Daniele Lecis, Enrico Fontanella, Elena Jachetti, Matteo Dugo, Tiziana Triulzi, Elda Tagliabue
Tumor growth and development is determined by both cancer cell–autonomous and microenvironmental mechanisms, including the contribution of infiltrating immune cells. Because the role of mast cells (MC) in this process is poorly characterized and ev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5961be16be787af28bb8b55bc9f2933
http://hdl.handle.net/10447/414607
http://hdl.handle.net/10447/414607
Autor:
Maria Teresa Majorini, Miguel Mano, Patrizia Pinciroli, Annalisa Conti, Mario P. Colombo, Claudia Chiodoni, Elda Tagliabue, Loris De Cecco, Enrico Fontanella, Giacomo Manenti, Domenico Delia, Daniele Lecis
Publikováno v:
Cell Death and Differentiation
Inhibitor of apoptosis (IAP) proteins constitute a family of conserved molecules that regulate both apoptosis and receptor signaling. They are often deregulated in cancer cells and represent potential targets for therapy. In our work, we investigated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e0993938d681c7d875ac2886beb5e14
https://doi.org/10.1038/s41418-018-0100-0
https://doi.org/10.1038/s41418-018-0100-0
Autor:
Ugo Pastorino, Francesca Andriani, Elena Landoni, Mavis Mensah, Luca Roz, Mauro Giacca, Miguel Mano, Enrico Fontanella, Daniele Lecis, Domenico Delia, Gabriella Sozzi, Rosalba Miceli, Matteo Dugo, Federica Facchinetti, Maria Teresa Majorini
Publikováno v:
Journal of Hematology & Oncology
Journal of Hematology & Oncology, Vol 11, Iss 1, Pp 1-17 (2018)
Journal of Hematology & Oncology, Vol 11, Iss 1, Pp 1-17 (2018)
Background Fibroblasts are crucial mediators of tumor-stroma cross-talk through synthesis and remodeling of the extracellular matrix and production of multiple soluble factors. Nonetheless, little is still known about specific determinants of fibrobl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c6e5769730fd402163c1f5fb31dea80
https://doi.org/10.1186/s13045-018-0594-4
https://doi.org/10.1186/s13045-018-0594-4