Staging Parkinson's disease according to the MNCD classification correlates with caregiver burden

Autor: Diego Santos‐García, Teresa deDeus Fonticoba, Carlos Cores Bartolomé, María J. Feal Painceiras, Iago García Díaz, María Cristina Íñiguez Alvarado, Jose Manuel Paz, Silvia Jesús, Marina Cosgaya, Juan García Caldentey, Nuria Caballol, Ines Legarda, Jorge Hernández Vara, Iria Cabo, Lydia López Manzanares, Isabel González Aramburu, Maria A. Ávila Rivera, Víctor Gómez Mayordomo, Víctor Nogueira, Julio Dotor García‐Soto, Carmen Borrué, Berta Solano Vila, María Álvarez Sauco, Lydia Vela, Sonia Escalante, Esther Cubo, Zebenzui Mendoza, Juan C. Martínez Castrillo, Pilar Sánchez Alonso, Maria G. Alonso Losada, Nuria López Ariztegui, Itziar Gastón, Jaime Kulisevsky, Manuel Seijo, Caridad Valero, Ruben Alonso Redondo, Maria Teresa Buongiorno, Carlos Ordás, Manuel Menéndez‐González, Darrian McAfee, Pablo Martinez‐Martin, Pablo Mir, COPPADIS Study Group

Publikováno v: Brain and Behavior, Vol 13, Iss 12, Pp n/a-n/a (2023)

Abstract Background and objective Recently, we demonstrated that staging Parkinson's disease (PD) with a novel simple classification called MNCD, based on four axes (motor, non‐motor, cognition, and dependency) and five stages, correlated with dise

Externí odkaz: https://doaj.org/article/ff18adaf795b4fa18e371b0bac7f9d77

Genome-Wide Association Study of VKORC1 and CYP2C9 on acenocoumarol dose, stroke recurrence and intracranial haemorrhage in Spain

Autor: Elena Muiño, Victor Obach, Ana Calleja, Elena López-Cancio, Reyes de Torres-Chacón, Jara Cárcel-Márquez, Joan Martí-Fàbregas, Serafí Cambray, Maria Del Mar Freijo, Jerzy Krupinski, Maria-Teresa Buongiorno, Israel Fernandez-Cadenas, Natalia Cullell, Joan Montaner, Sarah Besora, Jessica Molina, Manuel Rodríguez-Yáñez, Silvia Tur, Jonathan González-Sánchez, Cristina Gallego-Fabrega, María Hernández-Pérez, Eva Giralt-Steinhauer, Javier Sotoca, José Castillo, Nuria-Paz Torres-Aguila, Jordi Jimenez-Conde, Caty Carrera, Maria-Àngels Font, Juan Antonio Cabezas, Francisco Purroy, Fernando Mancha, Tomás Sobrino, Cristofol Vives-Bauza, Juan F. Arenillas, Luis Prats-Sánchez, Pol Camps-Renom

Publikováno v: Repositorio Abierto de la UdL
Universitad de Lleida
Scientific Reports, Vol 10, Iss 1, Pp 1-7 (2020)
Digital.CSIC. Repositorio Institucional del CSIC
instname

Acenocoumarol is an oral anticoagulant with significant interindividual dose variations. Variants in CYP2C9 and VKORC1 have been associated with acenocoumarol maintenance dose. We analysed whether any of the 49 polymorphisms in CYP2C9 and VKORC1 prev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30596eb8e882d6d90f34f88d12eacce8
https://doi.org/10.1038/s41598-020-59641-9

High cerebrospinal tau levels are associated with the rs242557 tau gene variant and low cerebrospinal β-amyloid in Parkinson disease

Autor: Francesc Valldeoriola, Manel Fernández, José Ríos, María José Martí, Yaroslau Compta, Esteban Muñoz, Maria Teresa Buongiorno, Ana Cámara, Eduardo Tolosa, Mario Ezquerra

Publikováno v: Neuroscience letters. 487(2)

Cerebrospinal fluid (CSF) tau and phospho-tau levels have been associated with certain tau gene variants and low CSF amyloid-β (Aβ) levels in Alzheimer disease (AD), constituting potential biomarkers of molecular mechanisms underlying neurodegenera

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81ebe08ec660acc0a3eac3ac90edffaf
https://pubmed.ncbi.nlm.nih.gov/20951764