Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Maria Teresa Bezem"'
Autor:
Aurora Martinez, Maria Teresa Bezem, Fredrik Gullaksen Johannessen, Michael J. Sailor, Trond-André Kråkenes
Publikováno v:
Molecular Pharmaceutics
Tyrosine hydroxylase (TH) is the enzyme catalyzing the rate-limiting step in the synthesis of dopamine in the brain. Developing enzyme replacement therapies using TH could therefore be beneficial to patient groups with dopamine deficiency, and the us
Publikováno v:
ACS Applied Materials & Interfaces. 10:3200-3209
A porous Si (pSi) microparticle-based delivery system is investigated, and the intrinsic luminescence from the particles is employed as a probe to monitor the release of a model protein payload, bovine serum albumin (BSA). The microparticles consist
Autor:
Ming Ying, Maria Teresa Bezem, Aurora Martinez, Lars Herfindal, Didier Betbeder, Edvin Tang Gundersen, Ana Jorge-Finnigan, Fredrik Gullaksen Johannessen, Kunwar Jung-KC
Publikováno v:
Bioconjugate chemistry. 29(2)
Enzyme replacement therapy (ERT) is a therapeutic approach envisioned decades ago for the correction of genetic disorders, but ERT has been less successful for the correction of disorders with neurological manifestations. In this work, we have tested
Stable preparations of tyrosine hydroxylase provide the solution structure of the full-length enzyme
Autor:
Romain Meyer, Aurora Martinez, Lars Skjærven, Marte I. Flydal, Petri Kursula, Maria Teresa Bezem, Anne Baumann
Publikováno v:
Scientific Reports
Scientific reports 6(1), 30390 (2016). doi:10.1038/srep30390
Scientific reports 6(1), 30390 (2016). doi:10.1038/srep30390
Scientific reports 6(1), 30390(2016). doi:10.1038/srep30390
Tyrosine hydroxylase (TH) catalyzes the rate-limiting step in the biosynthesis of catecholamine neurotransmitters. TH is a highly complex enzyme at mechanistic, structural, and regulato
Tyrosine hydroxylase (TH) catalyzes the rate-limiting step in the biosynthesis of catecholamine neurotransmitters. TH is a highly complex enzyme at mechanistic, structural, and regulato