Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Maria T. Toczek"'
Publikováno v:
European Journal of Paediatric Neurology. 16:138-141
Background Frontal intermittent rhythmic delta activity (FIRDA) has been studied extensively in adults but published literature about its clinical correlates in children and adolescents is comparatively limited. Aims This study was performed to find
Autor:
Nusrat Ahsan, Leigh Ramos-Platt, Maria T. Toczek, Tena Rosser, Wendy G. Mitchell, Jay Desai, Megan M Langille
Publikováno v:
Journal of Child Neurology. 27:503-506
Association of occipital intermittent rhythmic delta activity with absence seizures has been well documented in the published literature. Two recent studies have also described an association with focal seizures. After obtaining approval from our Ins
Autor:
Robert Bonwetsch, Maria T. Toczek, Wayne C. Drevets, Giampiero Giovacchini, Anto Bagic, William H. Theodore, David A. Luckenbaugh, Gregor Hasler
Publikováno v:
Biological Psychiatry. 62:1258-1264
Background Major depressive disorder (MDD) is the most common comorbid psychiatric condition associated with temporal lobe epilepsy (TLE). Preclinical and clinical studies suggest that 5-HT 1A receptors play a role in the pathophysiology of both TLE
Autor:
William C. Eckelman, Marianna Spanaki, L. Lang, William H. Theodore, Maria T. Toczek, Margaret G. Der, S. Fazilat, Peter Herscovitch, Y. Ma, Leonid Kopylev, Richard E. Carson
Publikováno v:
Neurology. 60:749-756
Background: Activation of central serotonin (5-HT) 1A receptors, found in high density in brainstem raphe, hippocampus, and temporal neocortex, exerts an anticonvulsant effect in various experimental seizure models. To test the hypothesis that 5-HT 1
Autor:
William H. Theodore, Maria T. Toczek
Publikováno v:
Neurosurgery Clinics of North America. 13:71-86
Functional imaging using single photon emission CT and positron emission tomography have made important contributions to the evaluation of patients with medically intractable epilepsy and cortical dysplasia by identifying patients who previously were
Publikováno v:
Journal of Neurosurgery. 85:718-722
✓ Four cases of cerebellar hemorrhage complicating temporal lobectomy are presented. A case of postoperative hemorrhage located remote from the operative site as a complication of intracranial surgery is rare, especially when it involves the cerebe
Autor:
Giampiero, Giovacchini, Maria T, Toczek, Robert, Bonwetsch, Anto, Bagic, Lixin, Lang, Charles, Fraser, Pat, Reeves-Tyer, Peter, Herscovitch, William C, Eckelman, Richard E, Carson, William H, Theodore
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 46(7)
Preclinical studies suggest that serotonin 1A receptors (5-HT1A) play a role in temporal lobe epilepsy (TLE). Previous PET studies reported decreased 5-HT1A binding ipsilateral to epileptic foci but did not correct for the partial-volume effect (PVE)
Autor:
Giampiero, Giovacchini, Alicja, Lerner, Maria T, Toczek, Charles, Fraser, Kaizong, Ma, James C, DeMar, Peter, Herscovitch, William C, Eckelman, Stanley I, Rapoport, Richard E, Carson
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 45(9)
PET with 11C-arachidonic acid (AA) can be used to quantify neural signaling related to phospholipase A2 (PLA2). Animal studies suggest reduction in the activity of this signaling system with age. The aim of this study was to evaluate the effect of he
Publikováno v:
Epilepsia. 45(3)
Summary: Purpose: Studies using magnetic resonance imaging have shown that reduced hippocampal volume is associated with a history of febrile seizures, the duration of epilepsy, and the number of generalized tonic‐clonic seizures. It is uncertain w
Autor:
Ying Ma, Michael A. Channing, Stanley I. Rapoport, Alicja Mason, Michael C. J. Chang, Catherine Connolly, Arun L.W. Bokde, William C. Eckelman, Richard E. Carson, Margaret G. Der, Bik-Kee Vuong, Peter Herscovitch, Maria T. Toczek, Doris J. Doudet, Giampiero Giovacchini
Publikováno v:
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 22(12)
Arachidonic acid (AA) is an important second messenger involved in signal transduction mediated by phospholipase A2. The goal of this study was to establish an in vivo quantitative method to examine the role of AA in this signaling process in the hum