Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Maria T. Sánchez-Aparicio"'
Autor:
Mirco Schmolke, Jenish R. Patel, Elisa de Castro, Maria T. Sánchez-Aparicio, Melissa B. Uccellini, Jennifer C. Miller, Balaji Manicassamy, Takashi Satoh, Taro Kawai, Shizuo Akira, Miriam Merad, Adolfo García-Sastre
Publikováno v:
mBio, Vol 5, Iss 2 (2014)
ABSTRACT The cytoplasmic helicase RIG-I is an established sensor for viral 5′-triphosphorylated RNA species. Recently, RIG-I was also implicated in the detection of intracellular bacteria. However, little is known about the host cell specificity of
Externí odkaz:
https://doaj.org/article/5c8c7580d0d14579892faa77373b07c6
Autor:
Sunnie M Yoh, João I. Mamede, Derrick Lau, Narae Ahn, Maria T Sánchez-Aparicio, Joshua Temple, Andrew Tuckwell, Nina V. Fuchs, Gianguido C. Cianci, Laura Riva, Heather Curry, Xin Yin, Stéphanie Gambut, Lacy M. Simons, Judd F. Hultquist, Renate König, Yong Xiong, Adolfo García-Sastre, Till Böcking, Thomas J. Hope, Sumit K. Chanda
SUMMARYCyclic GMP-AMP synthase (cGAS) is a primary sensor of aberrant DNA that governs an innate immune signaling cascade, leading to the induction of the type-I interferon response. We have previously identified polyglutamine binding protein 1, PQBP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f207e1751338e188b0ab341b2dd6cbf
https://doi.org/10.1101/2022.01.10.472699
https://doi.org/10.1101/2022.01.10.472699
Autor:
Sunnie M. Yoh, João I. Mamede, Derrick Lau, Narae Ahn, Maria T. Sánchez-Aparicio, Joshua Temple, Andrew Tuckwell, Nina V. Fuchs, Gianguido C. Cianci, Laura Riva, Heather Curry, Xin Yin, Stéphanie Gambut, Lacy M. Simons, Judd F. Hultquist, Renate König, Yong Xiong, Adolfo García-Sastre, Till Böcking, Thomas J. Hope, Sumit K. Chanda
Publikováno v:
Molecular cell. 82(15)
We have previously described polyglutamine-binding protein 1 (PQBP1) as an adapter required for the cyclic GMP-AMP synthase (cGAS)-mediated innate response to the human immunodeficiency virus 1 (HIV-1) and other lentiviruses. Cytoplasmic HIV-1 DNA is
Autor:
Priya Luthra, Sebastian Aguirre, Benjamin C. Yen, Colette A. Pietzsch, Maria T. Sanchez-Aparicio, Bersabeh Tigabu, Lorraine K. Morlock, Adolfo García-Sastre, Daisy W. Leung, Noelle S. Williams, Ana Fernandez-Sesma, Alexander Bukreyev, Christopher F. Basler
Publikováno v:
mBio, Vol 8, Iss 2 (2017)
ABSTRACT Ebola virus (EBOV) protein VP35 inhibits production of interferon alpha/beta (IFN) by blocking RIG-I-like receptor signaling pathways, thereby promoting virus replication and pathogenesis. A high-throughput screening assay, developed to iden
Externí odkaz:
https://doaj.org/article/41d9ac72b3f848f2a58a74adb321bd3b