Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Maria Szrejder"'
Autor:
Irena Audzeyenka, Maria Szrejder, Dorota Rogacka, Stefan Angielski, Moin A. Saleem, Agnieszka Piwkowska
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Podocytes constitute an external layer of the glomerular filtration barrier, injury to which is a hallmark of renal disease. Mitochondrial dysfunction often accompanies podocyte damage and is associated with an increase in oxidative stress a
Externí odkaz:
https://doaj.org/article/3c41d022e2b84732bf31cc0b1d6e3a94
Autor:
Maria Szrejder, Marlena Typiak, Piotr Pikul, Irena Audzeyenka, Patrycja Rachubik, Dorota Rogacka, Magdalena Narajczyk, Agnieszka Piwkowska
Publikováno v:
European Journal of Cell Biology, Vol 102, Iss 2, Pp 151298- (2023)
Lactate has long been acknowledged to be a metabolic waste product, but it has more recently been found as a fuel energy source in mammalian cells. Podocytes are an important component of the glomerular filter, and their role in maintaining the struc
Externí odkaz:
https://doaj.org/article/b45f3704119d4ad8a356a2a1b2b58f89
Autor:
Patrycja Rachubik, Dorota Rogacka, Irena Audzeyenka, Maria Szrejder, Anna Topolewska, Michał Rychłowski, Agnieszka Piwkowska
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3952 (2023)
The permeability of the glomerular filtration barrier (GFB) is mainly regulated by podocytes and their foot processes. Protein kinase G type Iα (PKGIα) and adenosine monophosphate-dependent kinase (AMPK) affect the contractile apparatus of podocyte
Externí odkaz:
https://doaj.org/article/853aab4821a24859a8452f9a039a3ecb
Autor:
Patrycja Rachubik, Maria Szrejder, Dorota Rogacka, Irena Audzeyenka, Michał Rychłowski, Stefan Angielski, Agnieszka Piwkowska
Publikováno v:
Cellular Physiology and Biochemistry, Vol 51, Iss 1, Pp 393-410 (2018)
Background/Aims: Podocytes are dynamic polarized cells on the surface of glomerular capillaries that are an essential part of the glomerular filtration barrier. AMP-activated protein kinase (AMPK), a key regulator of glucose and fatty acid metabolism
Externí odkaz:
https://doaj.org/article/996d50aad58441e0b6f2ec4cd1c66069
Autor:
Dorota Rogacka, Patrycja Rachubik, Irena Audzeyenka, Tomasz Kulesza, Maria Szrejder, Dorota Myślińska, Stefan Angielski, Agnieszka Piwkowska
Publikováno v:
Cellular Signalling. 105:110622
Autor:
Dorota Rogacka, Stefan Angielski, Patrycja Rachubik, Maria Szrejder, Agnieszka Piwkowska, Michał Rychłowski, Irena Audzeyenka
Publikováno v:
Journal of Biochemistry
Podocytes, the principal component of the glomerular filtration barrier, regulate glomerular permeability to albumin via their contractile properties. Both insulin- and high glucose (HG)-dependent activation of protein kinase G type Iα (PKGIα) caus
Publikováno v:
Archives of biochemistry and biophysics. 714
The purinergic activation of P2 receptors initiates a powerful and rapid signaling cascade that contributes to the regulation of an array of physiological and pathophysiological processes in many organs, including the kidney. P2 receptors are broadly
Autor:
Patrycja Rachubik, Maria Szrejder, Dorota Rogacka, Marlena Typiak, Irena Audzeyenka, Małgorzata Kasztan, David M. Pollock, Stefan Angielski, Agnieszka Piwkowska
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1869:119301
Podocyte foot processes are an important cellular layer of the glomerular barrier that regulates glomerular permeability. Insulin via the protein kinase G type Iα (PKGIα) signaling pathway regulates the balance between contractility and relaxation
Autor:
Patrycja Rachubik, Dorota Rogacka, Agnieszka Piwkowska, Stefan Angielski, Maria Szrejder, Marlena Typiak, Irena Audzeyenka
Publikováno v:
Archives of biochemistry and biophysics. 709
The protein deacetylase sirtuin 1 (SIRT1) and adenosine monophosphate-dependent protein kinase (AMPK) play important roles in the development of insulin resistance. In glomerular podocytes, crosstalk between these two enzymes may be altered under hyp
Autor:
Irena Audzeyenka, Stefan Angielski, Dorota Rogacka, Maria Szrejder, Agnieszka Piwkowska, Michał Rychłowski, Patrycja Rachubik
Publikováno v:
Archives of biochemistry and biophysics. 695
Podocytes and their foot processes interlinked by slit diaphragms, constitute a continuous outermost layer of the glomerular capillary and seem to be crucial for maintaining the integrity of the glomerular filtration barrier. Purinergic signaling is