Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Maria Sundvall"'
Autor:
Linda Nissi, Sanni Tuominen, Johannes Routila, Teemu Huusko, Petra Ketonen, Maria Sundvall, Ilmo Leivo, Heikki Irjala, Heikki Minn, Tove J. Grönroos, Sami Ventelä
Publikováno v:
Cancer Medicine, Vol 13, Iss 21, Pp n/a-n/a (2024)
ABSTRACT Background xCT, also known as SLC7A11 (solute carrier Family 7 Member 11), is a cystine/glutamate antiporter protein that mediates regulated cell death and antioxidant defense. The aim of this study was to investigate the effect of xCT on th
Externí odkaz:
https://doaj.org/article/eb07ca8478a24ba99fc48fb427fd5f96
Autor:
Verneri Virtanen, Kreetta Paunu, Antti Kukkula, Saana Niva, Ylva Junila, Mervi Toriseva, Terhi Jokilehto, Sari Mäkelä, Riikka Huhtaniemi, Matti Poutanen, Ilkka Paatero, Maria Sundvall
Publikováno v:
Oncogenesis, Vol 12, Iss 1, Pp 1-12 (2023)
Abstract Lethal prostate cancer (PCa) is characterized by the presence of metastases and development of resistance to therapies. Metastases form in a multi-step process enabled by dynamic cytoskeleton remodeling. An actin cytoskeleton regulating gene
Externí odkaz:
https://doaj.org/article/bc81cdeac0e2439e9c19b849d1d94729
Autor:
Sanni Tuominen, Linda Nissi, Antti Kukkula, Johannes Routila, Teemu Huusko, Ilmo Leivo, Heikki Minn, Heikki Irjala, Eliisa Löyttyniemi, Sami Ventelä, Maria Sundvall, Tove J. Grönroos
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundTreatment resistance and relapse are common problems in head and neck squamous cell carcinoma (HNSCC). Except for p16, no clinically accepted prognostic biomarkers are available for HNSCC. New biomarkers predictive of recurrence and surviva
Externí odkaz:
https://doaj.org/article/e593201e187a47768d76a1ee1ab78441
Autor:
Vilhelmiina Juusti, Antti Rannikko, Anu Laurila, Maria Sundvall, Pekka Hänninen, Janne Kulpakko
Publikováno v:
Life, Vol 14, Iss 5, p 600 (2024)
Most of the annual 10 million cancer-related deaths are caused by metastatic disease. Survival rates for cancer are strongly dependent on the type of cancer and its stage at detection. Early detection remains a challenge due to the lack of reliable b
Externí odkaz:
https://doaj.org/article/8471733c109d4433af93a10c3b3bfe69
Autor:
Anniina Hyväkkä, Okko‐Sakari Kääriäinen, Tapio Utriainen, Eliisa Löyttyniemi, Kalle Mattila, Petri Reinikainen, Jorma Sormunen, Minna Jääskeläinen, Päivi Auvinen, Heikki Minn, Maria Sundvall
Publikováno v:
Cancer Medicine, Vol 12, Iss 4, Pp 4064-4076 (2023)
Abstract Background Radium‐233 dichloride is an alpha emitter that specifically targets bone metastases in prostate cancer. Results of a previously reported phase III randomized trial showed survival benefit for radium‐223 compared to best suppor
Externí odkaz:
https://doaj.org/article/988c21ee30f643d0a357eb178ee4fb33
Autor:
Önver A. Çetrez, Valerie DeMarinis, Maria Sundvall, Manuel Fernandez-Gonzalez, Liubov Borisova, David Titelman
Publikováno v:
Frontiers in Sociology, Vol 6 (2021)
This public mental health study highlights the interactions among social determinants and resilience on mental health, PTSD and acculturation among Iraqi refugees in Sweden 2012-2013.Objectives: The study aims to understand participants' health, resi
Externí odkaz:
https://doaj.org/article/28064f0ff1bc452fb8555aea445b76fa
Different responses of colorectal cancer cells to alternative sequences of cetuximab and oxaliplatin
Autor:
Elli Narvi, Katri Vaparanta, Anna Karrila, Deepankar Chakroborty, Sakari Knuutila, Arto Pulliainen, Maria Sundvall, Klaus Elenius
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Abstract Therapeutic protocols including EGFR antibodies in the context of oxaliplatin-based regimens have variable clinical effect in colorectal cancer. Here, we tested the effect of the EGFR antibody cetuximab in different sequential combinations w
Externí odkaz:
https://doaj.org/article/6509ba9e46f9450ab57d53a05d5f7f52
Autor:
Katriina Peltola, Maija Hollmen, Sanna-Mari Maula, Eeva Rainio, Raija Ristamäki, Marjaana Luukkaa, Jouko Sandholm, Maria Sundvall, Klaus Elenius, Päivi J. Koskinen, Reidar Grenman, Sirpa Jalkanen
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 11, Iss 7, Pp 629-636 (2009)
Pim-1 is an oncogenic serine/threonine kinase with poorly defined function in epithelial cancers. In this study, we determined 1) associations of Pim-1 expression with clinicopathological parameters including responsiveness to irradiation in squamoce
Externí odkaz:
https://doaj.org/article/f39f0703391348d1b7ab961cee659c25
Autor:
Kari J Kurppa, Matjaz Rokavec, Maria Sundvall, Pirkko-Liisa Kellokumpu-Lehtinen, Heikki Joensuu, Hiltrud Brauch, Klaus Elenius
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e102388 (2014)
A number of genetic variants have been linked to increased risk of breast cancer. Little is, however, known about the prognostic significance of hereditary factors. Here, we investigated the frequency and prognostic significance of two ERBB4 promoter
Externí odkaz:
https://doaj.org/article/a48ee157799c4ee89fbe08ab28602f03
Publikováno v:
Biochemical and Biophysical Research Communications. 669:10-18
Cancer is a profound medical concern and better treatments are needed for cancer patients. Therefore, new cancer targets are constantly being studied. These targets need not only be relevant for cancer progression, but their modulation needs to be to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b4242f1dabfee95930b4596f36aa491
https://doi.org/10.1016/j.bbrc.2023.05.079
https://doi.org/10.1016/j.bbrc.2023.05.079