Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Maria Strocchia"'
Autor:
Amer M. Zeidan, Daniel A. Pollyea, Uma Borate, Alberto Vasconcelos, Ravi Potluri, David Rotter, Zephirin Kiendrebeogo, Lona Gaugler, Thomas Prebet, Maria Strocchia, Gaetano Bonifacio, Clara Chen
Publikováno v:
Annals of Hematology. 102:749-754
Autor:
Katrin Fischer, Maria Strocchia, Stefania Terracciano, Gianluigi Lauro, Raffaele Riccio, Ines Bruno, Giuseppe Bifulco, Oliver Werz
Publikováno v:
ACS Medicinal Chemistry Letters. 6:187-191
The recently crystallized structure of microsomal prostaglandin E2 synthase 1 (mPGES-1) in complex with the inhibitor LVJ (PDB code: 4BPM) offered new structural information for the optimization of the previously identified lead compound 1 (IC50 = 4.
Autor:
Mariacarmela Vaccaro, Giuseppe Bifulco, Antonio Foglia, Raffaele Riccio, Carmela Saturnino, Ines Bruno, Maria Strocchia, Stefania Terracciano, Maria Giovanna Chini, Antonio Vassallo
Hsp90 C-terminal modulation represents an attractive strategy for the development of potent and safer antitumor compounds. Continuing our investigation on DHPM type inhibitors here we report a new set of potent C-terminal ligands which allowed us to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ad582da21979e014bfd84bf3db6e7f3
http://hdl.handle.net/11386/4675524
http://hdl.handle.net/11386/4675524
Autor:
Maria C. Vaccaro, Stefania Terracciano, Fabrizio Dal Piaz, Maria Giovanna Chini, Maria Strocchia, Antonio Vassallo, Antonietta Leone, Giuseppe Bifulco, Raffaele Riccio, Ines Bruno
Hsp90 C-terminal ligands are potential new anti-cancer drugs alternative to the more studied N-terminal inhibitors. Here we report the identification of a new dihydropyrimidinone binding the C-terminus, which is not structurally related to other well
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94b7f0a43306fad329f164d37a52edf9
http://hdl.handle.net/11386/4651189
http://hdl.handle.net/11386/4651189
Autor:
Gianluigi, Lauro, Maria, Strocchia, Stefania, Terracciano, Ines, Bruno, Katrin, Fischer, Carlo, Pergola, Oliver, Werz, Raffaele, Riccio, Giuseppe, Bifulco
Publikováno v:
European journal of medicinal chemistry. 80
Agents targeting microsomal prostaglandin E2 synthase-1 (mPGES-1) would inhibit only PGE2 production induced by inflammatory stimuli and thus could represent a valuable alternative to non-steroidal anti-inflammatory drugs (NSAIDs) as they should be f
Autor:
Oliver Werz, Gianluigi Lauro, Ines Bruno, Raffaele Riccio, Carlo Pergola, Katrin Fischer, Stefania Terracciano, Giuseppe Bifulco, Maria Strocchia
Agents targeting microsomal prostaglandin E2 synthase-1 (mPGES-1) would inhibit only PGE2 production induced by inflammatory stimuli and thus could represent a valuable alternative to non-steroidal anti-inflammatory drugs (NSAIDs) as they should be f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61e8647dd3dd8da8aac5fb3a3db36c42
http://hdl.handle.net/11386/4504857
http://hdl.handle.net/11386/4504857