Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Maria Stella Pennisi"'
Autor:
Maria Stella Pennisi, Sandra Di Gregorio, Elena Tirrò, Chiara Romano, Andrea Duminuco, Bruno Garibaldi, Gaetano Giuffrida, Livia Manzella, Paolo Vigneri, Giuseppe A. Palumbo
Publikováno v:
Hematology Reports, Vol 15, Iss 2, Pp 317-324 (2023)
Essential thrombocythemia (ET) and primary myelofibrosis (PMF) are two of the main BCR-ABL1-negative chronic myeloproliferative neoplasms (MPNs) characterized by abnormal megakaryocytic proliferation. Janus kinase 2 (JAK2) mutations are detected in 5
Externí odkaz:
https://doaj.org/article/0f2895a965554aea8fd58e369039bcf1
Autor:
Michele Massimino, Elena Tirrò, Stefania Stella, Livia Manzella, Maria Stella Pennisi, Chiara Romano, Silvia Rita Vitale, Adriana Puma, Cristina Tomarchio, Sandra Di Gregorio, Agostino Antolino, Francesco Di Raimondo, Paolo Vigneri
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Chronic Myeloid Leukemia (CML) is a hematological disorder characterized by the clonal expansion of a hematopoietic stem cell carrying the Philadelphia chromosome that juxtaposes the BCR and ABL1 genes. The ensuing BCR-ABL1 chimeric oncogene is chara
Externí odkaz:
https://doaj.org/article/e64984d411ed458d9ee29e056ad88a5f
Autor:
Elena Tirrò, Michele Massimino, Chiara Romano, Federica Martorana, Maria Stella Pennisi, Stefania Stella, Giuliana Pavone, Sandra Di Gregorio, Adriana Puma, Cristina Tomarchio, Silvia Rita Vitale, Livia Manzella, Paolo Vigneri
Publikováno v:
Frontiers in Oncology, Vol 10 (2021)
Glioblastoma multiforme (GBM) is the most common primary brain malignancy and is often resistant to conventional treatments due to its extensive cellular heterogeneity. Thus, the overall survival of GBM patients remains extremely poor. Insulin-like g
Externí odkaz:
https://doaj.org/article/5b3b2a650bd34cddbfe18451893beb66
Autor:
Stefania Stella, Silvia Rita Vitale, Fabio Stagno, Michele Massimino, Adriana Puma, Cristina Tomarchio, Maria Stella Pennisi, Elena Tirrò, Chiara Romano, Francesco Di Raimondo, Emma Cacciola, Rossella Cacciola, Livia Manzella
Publikováno v:
Diagnostics, Vol 12, Iss 5, p 1051 (2022)
Background: Detection of BCR-ABL1 transcript level via real-time quantitative-polymerase-chain reaction (Q-PCR) is a clinical routine for disease monitoring, assessing Tyrosine Kinase Inhibitor therapy efficacy and predicting long-term response in ch
Externí odkaz:
https://doaj.org/article/f7d7cb5661ca4f51a9017dfe1bdc1026
Autor:
Michele Massimino, Stefania Stella, Elena Tirrò, Chiara Romano, Maria Stella Pennisi, Adriana Puma, Livia Manzella, Antonino Zanghì, Fabio Stagno, Francesco Di Raimondo, Paolo Vigneri
Publikováno v:
Molecular Cancer, Vol 17, Iss 1, Pp 1-15 (2018)
Abstract The introduction of ABL Tyrosine Kinase Inhibitors (TKIs) has significantly improved the outcome of Chronic Myeloid Leukemia (CML) patients that, in large part, achieve satisfactory hematological, cytogenetic and molecular remissions. Howeve
Externí odkaz:
https://doaj.org/article/9b21a4b502ea48ec89c59850edc2e6d1
Autor:
Stefania Stella, Silvia Rita Vitale, Michele Massimino, Adriana Puma, Cristina Tomarchio, Maria Stella Pennisi, Elena Tirrò, Chiara Romano, Federica Martorana, Fabio Stagno, Francesco Di Raimondo, Livia Manzella
Publikováno v:
Diagnostics, Vol 11, Iss 8, p 1502 (2021)
Molecular testing of the BCR-ABL1 transcript via real-time quantitative-polymerase-chain-reaction is the most sensitive approach for monitoring the response to tyrosine-kinase-inhibitors therapy in chronic myeloid leukaemia (CML) patients. Each stage
Externí odkaz:
https://doaj.org/article/605f9d39700947e9b08dab2fb0be37e4
Autor:
Maria Stella Pennisi, Stefania Stella, Silvia Rita Vitale, Adriana Puma, Sandra Di Gregorio, Chiara Romano, Elena Tirrò, Michele Massimino, Agostino Antolino, Sergio Siragusa, Donato Mannina, Stefana Impera, Caterina Musolino, Giuseppe Mineo, Bruno Martino, Valentina Zammit, Francesco Di Raimondo, Livia Manzella, Fabio Stagno, Paolo Vigneri
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
In Chronic Myeloid Leukemia (CML), successful treatment requires accurate molecular monitoring to evaluate disease response and provide timely interventions for patients failing to achieve the desired outcomes. We wanted to determine whether measurin
Externí odkaz:
https://doaj.org/article/3e56e6cdd1d04b3297ce06df9e7579b6
Autor:
Giuseppe A. Palumbo, Stefania Stella, Maria Stella Pennisi, Cristina Pirosa, Elisa Fermo, Sonia Fabris, Daniele Cattaneo, Alessandra Iurlo
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
The hallmark of BCR-ABL1-negative myeloproliferative neoplasms (MPNs) is the presence of a driver mutation in JAK2, CALR, or MPL gene. These genetic alterations represent a key feature, useful for diagnostic, prognostic and therapeutical approaches.
Externí odkaz:
https://doaj.org/article/2b7c577213dd4d8dbd6fd4e543daff1f
Autor:
Elena Tirrò, Michele Massimino, Chiara Romano, Maria Stella Pennisi, Stefania Stella, Silvia Rita Vitale, Annamaria Fidilio, Livia Manzella, Nunziatina Laura Parrinello, Fabio Stagno, Giuseppe Alberto Palumbo, Piera La Cava, Alessandra Romano, Francesco Di Raimondo, Paolo G. Vigneri
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Inotuzumab ozogamicin (IO) is an anti-CD22 calicheamicin immunoconjugate that has been recently approved for the treatment of relapsed or refractory B-Acute Lymphoblastic Leukemia (r/r B-ALL). We employed both immortalized and primary cells derived f
Externí odkaz:
https://doaj.org/article/76bf0ae747314654a8d3c790630999a9
Autor:
Chiara Romano, Sandra Di Gregorio, Maria Stella Pennisi, Elena Tirrò, Giuseppe Broggi, Rosario Caltabiano, Livia Manzella, Martino Ruggieri, Paolo Vigneri, Antonio Di Cataldo
Publikováno v:
Molecular biology reports. 49(9)
Multiple primary malignancies (MPM) are defined as tumors originating in the same individual without any correlation between them. In addition to morphological and immunohistochemical analyses, sensitive DNA sequencing methods such as next generation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cf455e5056152584e5861c0bb2458c6
https://pubmed.ncbi.nlm.nih.gov/35715605
https://pubmed.ncbi.nlm.nih.gov/35715605