Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Maria Stefania S. Ninniri"'
Autor:
Angela Coxon, Gloria Juan, John D. Crispino, Kelly Hanestad, William C. Wayne, Christian Marinaccio, Maria Stefania S. Ninniri, Hung-Kam Cheung, Marc Payton
Aurora kinase A and B have essential and non-overlapping roles in mitosis, with elevated expression in a subset of human cancers, including acute myeloid leukemia (AML). In this study, pan-aurora kinase inhibitor (AKI) AMG 900 distinguishes itself as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7f3edba6e138bbbe2cb5592dc3aed4b
https://doi.org/10.1158/1535-7163.c.6537892.v1
https://doi.org/10.1158/1535-7163.c.6537892.v1
Autor:
Angela Coxon, Gloria Juan, John D. Crispino, Kelly Hanestad, William C. Wayne, Christian Marinaccio, Maria Stefania S. Ninniri, Hung-Kam Cheung, Marc Payton
Supplementary Figure S1 shows the cellular effects of AKIs and anti-leukemic agents across a panel of human AML cell lines. Supplementary Figure S2 shows expression of aurora-A and aurora-B protein levels in four AML cell lines. Supplementary Figure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d3f63166b104dffe567bb8db1d0a31f
https://doi.org/10.1158/1535-7163.22504900.v1
https://doi.org/10.1158/1535-7163.22504900.v1
Autor:
Brian Belmontes, Jodi Moriguchi, Grace Chung, Jan Sun, Maria Stefania S. Ninniri, Kelly Hanestad, Kui Chen, John D. McCarter, Upendra P. Dahal, Sudipa Ghimire-Rijal, Yue Hao, Christopher P. Mohr, Xinchao Yu, Matthew G. Rees, Melissa Ronan, Jennifer Roth, Sheroy Minocherhomji, Jennifer R. Allen, Matthew P. Bourbeau, Paul E. Hughes, Nuria A Tamayo, Marc N. Payton
Publikováno v:
Cancer Research. 83:516-516
Chromosomal instability (CIN) is a hallmark of human cancers and is caused by persistent errors in chromosome segregation during mitosis. Aggressive types of human cancer such as high-grade serous ovarian cancer and triple-negative breast cancer have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f35caf28e90cc86d95a85ee0af8c0a54
https://doi.org/10.1158/1538-7445.am2023-516
https://doi.org/10.1158/1538-7445.am2023-516
Autor:
Nuria A. Tamayo, Matthew P. Bourbeau, Jennifer R. Allen, Kate S. Ashton, Jian Jeffrey Chen, Matthew R. Kaller, Thomas T. Nguyen, Nobuko Nishimura, Liping H. Pettus, Mary Walton, Brian Belmontes, Jodi Moriguchi, Kui Chen, John D. McCarter, Kelly Hanestad, Grace Chung, Maria Stefania S. Ninniri, Jan Sun, Leszek Poppe, Chris Spahr, John Hui, Lei Jia, Tian Wu, Upendra P. Dahal, Katheryne Z. Edson, Marc Payton
Publikováno v:
Journal of medicinal chemistry. 65(6)
Chromosomal instability (CIN) is a hallmark of cancer that results from errors in chromosome segregation during mitosis. Targeting of CIN-associated vulnerabilities is an emerging therapeutic strategy in drug development. KIF18A, a mitotic kinesin, h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58b073c07dd2504a104516bc02d88ed4
https://pubmed.ncbi.nlm.nih.gov/35286090
https://pubmed.ncbi.nlm.nih.gov/35286090
Autor:
Maria Stefania S. Ninniri, Christian Marinaccio, Kelly Hanestad, Hung Kam Cheung, John D. Crispino, Gloria Juan, William Wayne, Marc Payton, Angela Coxon
Publikováno v:
Molecular Cancer Therapeutics. 17:2575-2585
Aurora kinase A and B have essential and non-overlapping roles in mitosis, with elevated expression in a subset of human cancers, including acute myeloid leukemia (AML). In this study, pan-aurora kinase inhibitor (AKI) AMG 900 distinguishes itself as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ad318e426be94ae52563762c0757126
https://doi.org/10.1158/1535-7163.mct-18-0186
https://doi.org/10.1158/1535-7163.mct-18-0186