Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Maria Stefania Brignone"'
Autor:
Caterina Veroni, Stefania Olla, Maria Stefania Brignone, Chiara Siguri, Alessia Formato, Manuela Marra, Rosa Manzoli, Maria Carla Macario, Elena Ambrosini, Enrico Moro, Cristina Agresti
Publikováno v:
Biomolecules, Vol 14, Iss 4, p 443 (2024)
A considerable effort has been spent in the past decades to develop targeted therapies for the treatment of demyelinating diseases, such as multiple sclerosis (MS). Among drugs with free radical scavenging activity and oligodendrocyte protecting effe
Externí odkaz:
https://doaj.org/article/be47b9891dfd476689ff304711d8e573
The CaMKII/MLC1 Axis Confers Ca2+-Dependence to Volume-Regulated Anion Channels (VRAC) in Astrocytes
Autor:
Maria Stefania Brignone, Angela Lanciotti, Antonio Michelucci, Cinzia Mallozzi, Serena Camerini, Luigi Catacuzzeno, Luigi Sforna, Martino Caramia, Maria Cristina D’Adamo, Marina Ceccarini, Paola Molinari, Pompeo Macioce, Gianfranco Macchia, Tamara Corinna Petrucci, Mauro Pessia, Sergio Visentin, Elena Ambrosini
Publikováno v:
Cells, Vol 11, Iss 17, p 2656 (2022)
Astrocytes, the main glial cells of the central nervous system, play a key role in brain volume control due to their intimate contacts with cerebral blood vessels and the expression of a distinctive equipment of proteins involved in solute/water tran
Externí odkaz:
https://doaj.org/article/9df8afeeb8104fff9e24465d1bdf7fdc
Autor:
Xabier Elorza-Vidal, Sònia Sirisi, Héctor Gaitán-Peñas, Carla Pérez-Rius, Marta Alonso-Gardón, Mercedes Armand-Ugón, Angela Lanciotti, Maria Stefania Brignone, Esther Prat, Virginia Nunes, Elena Ambrosini, Xavier Gasull, Raúl Estévez
Publikováno v:
Neurobiology of Disease, Vol 119, Iss , Pp 88-99 (2018)
Megalencephalic leukoencephalopathy with subcortical cysts (MLC) is a rare type of leukodystrophy caused by mutations in either MLC1 or GLIALCAM genes. Previous work indicated that chloride currents mediated by the volume-regulated anion channel (VRA
Externí odkaz:
https://doaj.org/article/07016d228ca04064967df3945f315c92
Autor:
Angela Lanciotti, Maria Stefania Brignone, Marcello Belfiore, Sandra Columba-Cabezas, Cinzia Mallozzi, Olimpia Vincentini, Paola Molinari, Tamara Corinna Petrucci, Sergio Visentin, Elena Ambrosini
Publikováno v:
Cells, Vol 9, Iss 6, p 1425 (2020)
Astrocytes, the most numerous cells of the central nervous system, exert critical functions for brain homeostasis. To this purpose, astrocytes generate a highly interconnected intercellular network allowing rapid exchange of ions and metabolites thro
Externí odkaz:
https://doaj.org/article/d18ec98eca484ffbac212bf16948f6c9
Publikováno v:
Neural Regeneration Research, Vol 20, Iss 7, Pp 2008-2010 (2025)
Externí odkaz:
https://doaj.org/article/d858c92096ec4e2a8da221f7e8fb333a
Autor:
Angela Lanciotti, Maria Stefania Brignone, Serena Camerini, Barbara Serafini, Gianfranco Macchia, Carla Raggi, Paola Molinari, Marco Crescenzi, Marco Musumeci, Massimo Sargiacomo, Francesca Aloisi, Tamara Corinna Petrucci, Elena Ambrosini
Publikováno v:
Neurobiology of Disease, Vol 37, Iss 3, Pp 581-595 (2010)
Megalencephalic leukoencephalopathy with subcortical cysts (MLC) is a rare congenital leukodystrophy caused by mutations in the MLC1 gene that encodes a membrane protein of unknown function. In the brain MLC1 protein is mainly expressed in astrocyte
Externí odkaz:
https://doaj.org/article/73ef5326cd4743cf83011c1b451a05f7
Autor:
Maria Stefania Brignone, Angela Lanciotti, Antonio Michelucci, Cinzia Mallozzi, Serena Camerini, Luigi Catacuzzeno, Luigi Sforna, Martino Caramia, Maria Cristina D'Adamo, Marina Ceccarini, Paola Molinari, Pompeo Macioce, Gianfranco Macchia, Tamara Corinna Petrucci, Mauro Pessia, Sergio Visentin, Elena Ambrosini
MLC1 is a membrane protein highly expressed by brain perivascular astrocytes. Mutations in the MLC1 gene account for megalencephalic leukoencephalopathy with subcortical cysts (MLC), an incurable leukodystrophy characterized by macrocephaly, brain ed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5f7cf797323afa20871d8b06f2122b3
https://doi.org/10.21203/rs.3.rs-1195518/v1
https://doi.org/10.21203/rs.3.rs-1195518/v1
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 23, Iss 274, p 274 (2022)
International Journal of Molecular Sciences, Vol 23, Iss 274, p 274 (2022)
Astrocytes are very versatile cells, endowed with multitasking capacities to ensure brain homeostasis maintenance from brain development to adult life. It has become increasingly evident that astrocytes play a central role in many central nervous sys
Autor:
Caterina Veroni, Raúl Estévez, Marco Sbriccoli, Xabier Elorza-Vidal, Barbara Serafini, Paola Molinari, Tamara C. Petrucci, Angela Lanciotti, Maria Stefania Brignone, Cinzia Mallozzi, Elena Ambrosini
Publikováno v:
Molecular Neurobiology. 56:8237-8254
Megalencephalic leukoencephalopathy with subcortical cysts protein-1 (MLC1) is a membrane protein expressed by perivascular astrocytes. MLC1 mutations cause MLC, an incurable leukodystrophy characterized by macrocephaly, brain edema, cysts, myelin va
Autor:
Carmen Troiano, Mario Falchi, Maria Stefania Brignone, Sergio Visentin, Cristina Lanni, Chiara De Nuccio, Michela Rosini, Antonietta Bernardo, Anita Greco, Luisa Minghetti, Filippo Basagni, Melania Maria Serafini
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 7216, p 7216 (2020)
Volume 21
Issue 19
International Journal of Molecular Sciences, Vol 21, Iss 7216, p 7216 (2020)
Volume 21
Issue 19
An adequate protection from oxidative and inflammatory reactions, together with the promotion of oligodendrocyte progenitor (OP) differentiation, is needed to recover from myelin damage in demyelinating diseases. Mitochondria are targets of inflammat