Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Maria Speranza, Desole"'
Autor:
Gaia Rocchitta, Pier Andrea Serra, Robert D. O'Neill, Maria Speranza Desole, Rossana Migheli, Marco Pirisinu, Gianfranco Bazzu, Ylenia Spissu, Manuel Zinellu, Ottavio Secchi
Publikováno v:
Sensors, Vol 13, Iss 7, Pp 9522-9535 (2013)
Ethyl alcohol may be considered one of the most widespread central nervous system (CNS) depressants in Western countries. Because of its toxicological and neurobiological implications, the detection of ethanol in brain extracellular fluid (ECF) is of
Externí odkaz:
https://doaj.org/article/88ee804c085a4cdab9e42d22724169ef
Autor:
Maria Domenica Alvau, Manuel Zinellu, Giulia Maria Grazia Puggioni, Gaia Giovanna Maria Rocchitta, Gianfranco Bazzu, Maria Speranza Desole, Giammario Calia, Pier Andrea Serra, Rossana Migheli, Giulia Mercanti, Pietro Giusti
Publikováno v:
Brain Research. 1538:159-171
The neurotoxin MPTP is known to induce dopamine release and depletion of ATP in the striatum of rats. Therefore, we studied the changes induced by MPTP and pargyline protection both on striatal dopamine release and on extracellular energy metabolites
Autor:
Gaia Giovanna Maria Rocchitta, Ottavio Secchi, Donatella Farina, Pier Andrea Serra, Gianfranco Bazzu, Maria Domenica Alvau, Rossana Migheli, Robert D. O'Neill, Maria Speranza Desole, Giovanna Maria Calia
Publikováno v:
Analytical Chemistry. 84:7072-7079
Ethanol is one of the most widespread psychotropic agents in western society. While its psychoactive effects are mainly associated with GABAergic and glutamatergic systems, the positive reinforcing properties of ethanol are related to activation of m
Autor:
Rossana Migheli, Morena Zusso, Ylenia Spissu, Jessica Grigoletto, Egidio Miele, Maria Speranza Desole, Pier Andrea Serra, Giammario Calia, Gaia Giovanna Maria Rocchitta, Patrizia Debetto, Giulia Maria Grazia Puggioni, Gianfranco Bazzu
Publikováno v:
CNS & Neurological Disorders - Drug Targets. 9:482-490
The classical animal models of Parkinson's disease (PD) rely on the use of neurotoxins, including 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), 6-hydroxydopamine and, more recently, the agricultural chemicals paraquat and rotenone, to deplete
Autor:
Gianfranco Bazzu, Giulia Maria Grazia Puggioni, R Migheli, John P. Lowry, Robert D. O’Neill, Pier Andrea Serra, Gaia Giovanna Maria Rocchitta, Maria Speranza Desole, Sonia Dedola, Giammario Calia
Publikováno v:
Analytical Chemistry. 81:2235-2241
A miniaturized biotelemetric device for the amperometric detection of brain tissue oxygen is presented. The new system, derived from a previous design, has been coupled with a carbon microsensor for the real-time detection of dissolved O(2) in the st
Autor:
Giammario Calia, Sonia Dedola, Giulia Maria Grazia Puggioni, Gaia Giovanna Maria Rocchitta, Pier Andrea Serra, Giovanni Esposito, Rossana Migheli, John P. Lowry, Gianfranco Bazzu, Egidio Miele, Robert D. O'Neill, Maria Speranza Desole
Publikováno v:
Analytical Biochemistry. 380:323-330
A novel dual channel in vitro apparatus, derived from a previously described design, has been coupled with dopamine (DA) microsensors for the flow-through detection of DA secreted from PC12 cells. The device, including two independent microdialysis c
Publikováno v:
Parkinsonism & Related Disorders. 14:S189-S193
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) is known to cause parkinsonism in humans and this fact is a major incentive for using this toxin as an animal model to study the pathogenesis of Parkinson's disease (PD). Although the monkey MPTP mo
Autor:
Maria Clorinda Mazzarino, Egidio Miele, Maria Speranza Desole, Nuccio Testa, Bianca Marchetti, Pier Andrea Serra, Serena Cioni, Salvo Caniglia, Francesca L'Episcopo, Florinda Gennuso, Cataldo Tirolo, Gaia Giovanna Maria Rocchitta, Maria C. Morale
Publikováno v:
Annals of the New York Academy of Sciences. 1057:296-318
Alterations in developmental programming of neuroendocrine and immune system function may critically modulate vulnerability to various diseases. In particular, genetic factors, including gender, may interact with early life events such as exposure to
Autor:
Maddalena Miele, Luigi Solinas, Giuseppe Susini, Egidio Miele, Pier Andrea Serra, Gaia Giovanna Maria Rocchitta, Maria Speranza Desole, Rossana Migheli, M Rosaria Delogu
Publikováno v:
Journal of Pharmacological Sciences, Vol 95, Iss 3, Pp 299-304 (2004)
The Ca2+ sensitizer levosimendan (LEV) improves myocardial contractility by enhancing the sensitivity of the contractile apparatus to Ca2+. In addition, LEV promotes Ca2+ entry through L-type channels in human cardiac myocytes. In this study, which w
Autor:
Pier Andrea Serra, Maria Rosaria Delogu, Rossana Migheli, Maddalena Miele, Maria Grazia Taras, Giovanni Esposito, Maria Pina Mura, Gaia Giovanna Maria Rocchitta, Egidio Miele, Maria Speranza Desole
Publikováno v:
Neuroscience Letters. 353:5-8
We showed previously, using in vitro microdialysis, that activation of the nitric oxide (NO)/cyclic GMP pathway was the underlying mechanism of exogenous NO-induced dopamine (DA) secretion from PC12 cells. In this study, infusion of the potential per