Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Maria Sol Herrera-Cruz"'
Autor:
Maria Sol Herrera-Cruz, Megan C. Yap, Nasser Tahbaz, Keelie Phillips, Laurel Thomas, Gary Thomas, Thomas Simmen
Publikováno v:
Biology Direct, Vol 16, Iss 1, Pp 1-16 (2021)
Abstract Background Rab32 is a small GTPase associated with multiple organelles but is particularly enriched at the endoplasmic reticulum (ER). Here, it controls targeting to mitochondria-ER contacts (MERCs), thus influencing composition of the mitoc
Externí odkaz:
https://doaj.org/article/a331bf03648046b0ae7fd0d42d92e7f2
Autor:
Maria Sol Herrera-Cruz, Thomas Simmen
Publikováno v:
Frontiers in Oncology, Vol 7 (2017)
Following the discovery of the mitochondria-associated membrane (MAM) as a hub for lipid metabolism in 1990 and its description as one of the first examples for membrane contact sites at the turn of the century, the past decade has seen the emergence
Externí odkaz:
https://doaj.org/article/9f7ab4bbf65343128e144c364e4daf0f
Autor:
Keelie Phillips, Laurel Thomas, Megan C. Yap, Maria Sol Herrera-Cruz, Nasser Tahbaz, Gary Thomas, Thomas Simmen
Publikováno v:
Biology Direct
Biology Direct, Vol 16, Iss 1, Pp 1-16 (2021)
Biology Direct, Vol 16, Iss 1, Pp 1-16 (2021)
Background Rab32 is a small GTPase associated with multiple organelles but is particularly enriched at the endoplasmic reticulum (ER). Here, it controls targeting to mitochondria-ER contacts (MERCs), thus influencing composition of the mitochondria-a
Autor:
Araya Ruangkittisakul, Maria Sol Herrera-Cruz, Shairaz Baksh, Eliana Lucchinetti, Thomas Simmen, Dimitar Ourdev, Michael Zaugg, Tomás Gutiérrez, Carolina Ortiz-Sandoval, Arun Raturi, Phing-How Lou, Klaus Ballanyi, Kevin Gesson, Nasser Tahbaz, Jeremy P. Rockley
Publikováno v:
The Journal of Cell Biology
Cancer cells are critically dependent on ER–mitochondria Ca2+ flux that regulates their bioenergetics. Here, Raturi et al. identify the ER oxidoreductase TMX1 as a thiol-dependent regulator of this intracellular signaling mechanism within cancer ce
Publikováno v:
Small GTPases
We have shown that multiple sclerosis (MS) and endoplasmic reticulum (ER) stress induce Rab32, an ER/mitochondria-localized small GTPase. High levels of both dominant-active (Q85L) or dominant-inactive (T39N) Rab32 are toxic to neurons. While Rab32Q8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fab46a8632a6abe661ca047f0b7b9ef
https://europepmc.org/articles/PMC7549637/
https://europepmc.org/articles/PMC7549637/
Autor:
Maria Sol Herrera-Cruz, Thomas Simmen
Publikováno v:
Current opinion in cell biology. 53
Mitochondria-endoplasmic reticulum (ER) contacts (MERCs), biochemically isolated as the mitochondria-associated membrane (MAM), were discovered on electron micrographs in the early 1950s. Since the 1990s, we know that the two organelles exchange lipi
Publikováno v:
Advances in experimental medicine and biology. 997
The discovery of proteins regulating ER-mitochondria tethering including phosphofurin acidic cluster sorting protein 2 (PACS-2) and mitofusin-2 has pushed contact sites between the endoplasmic reticulum (ER) and mitochondria into the spotlight of cel
Autor:
Thomas Simmen, Maria Sol Herrera-Cruz
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9789811045660
The discovery of proteins regulating ER-mitochondria tethering including phosphofurin acidic cluster sorting protein 2 (PACS-2) and mitofusin-2 has pushed contact sites between the endoplasmic reticulum (ER) and mitochondria into the spotlight of cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::928c003725f38b8505a9eb27e59c2cca
https://doi.org/10.1007/978-981-10-4567-7_2
https://doi.org/10.1007/978-981-10-4567-7_2
Autor:
Thomas Simmen, Maria Sol Herrera-Cruz
Publikováno v:
Biology Direct
The past decade has seen dramatic progress in our understanding of membrane contact sites (MCS). Important examples of these are endoplasmic reticulum (ER)-mitochondria contact sites. ER-mitochondria contacts have originally been discovered in mammal