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Akademický článek

Modulation of immune responses by the tumor suppressor p53

Autor: Julie Lowe, Maria Shatz, Michael A. Resnick, Daniel Menendez

Publikováno v: BioDiscovery, Vol 8, Iss , Pp 1-12 (2013)

The commonly held view of the tumor suppressor p53 as a regulator of cell proliferation, apoptosis and senescence has expanded greatly in recent years to cover many biological processes as well as external and internal stress responses. Since the dis

Externí odkaz: https://doaj.org/article/4d11fdacf62949aea6339d37b864db23

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Akademický článek

The Toll-like receptor gene family is integrated into human DNA damage and p53 networks.

Autor: Daniel Menendez, Maria Shatz, Kathleen Azzam, Stavros Garantziotis, Michael B Fessler, Michael A Resnick

Publikováno v: PLoS Genetics, Vol 7, Iss 3, p e1001360 (2011)

In recent years the functions that the p53 tumor suppressor plays in human biology have been greatly extended beyond "guardian of the genome." Our studies of promoter response element sequences targeted by the p53 master regulatory transcription fact

Externí odkaz: https://doaj.org/article/1c851161da124fd6ab494edb49d4b45a

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Supplementary Figures 1 - 4 from p53 and NF-κB Coregulate Proinflammatory Gene Responses in Human Macrophages

Autor: Michael A. Resnick, Michael B. Fessler, Stavros Garantziotis, Melissa A. Troester, Erin L. Kirk, Maria Shatz, Pierre R. Bushel, Daniel Menendez, Julie M. Lowe

PDF file - 249K, Figure S1. p53 activation by Nutlin-3 induces pro-inflammatory genes. Figure S2. NF-kB plays a role in gene regulation induced by Nutlin-3. Figure S3. Microarray analysis Nutlin-3 and LPS-treated macrophages identifies chemokine gene

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::572e21b214fef0ff96174ede4e57bbc4
https://doi.org/10.1158/0008-5472.22401287.v1

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Data from Differential Expression and Function of Caveolin-1 in Human Gastric Cancer Progression

Autor: Matthias P.A. Ebert, Roland M. Schmid, Moti Liscovitch, Maria Shatz, Katrin Mair, Michaela Hiber, Jie Chen, Mark Juhasz, Christoph Röcken, Xiangbin Xing, Elke Burgermeister

Caveolin-1 is a scaffold protein of caveolae that acts as a tumor modulator by interacting with cell adhesion molecules and signaling receptors. The role of caveolin-1 in the pathogenesis of gastric cancer (GC) is currently unknown. We show by confoc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::326a2f44545a03e22465e0370e909b7f
https://doi.org/10.1158/0008-5472.c.6496067

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