Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Maria Shamin"'
Publikováno v:
Contact, Vol 4 (2021)
Saposins are lipid transfer proteins required for the degradation of sphingolipids in the lysosome. These small proteins bind lipids by transitioning from a closed, monomeric state to an open conformation exposing a hydrophobic surface that binds and
Externí odkaz:
https://doaj.org/article/f16a0239b43e4d07a7ee17ab3e4f21b6
Autor:
Christopher H. Douse, Stuart Bloor, Yangci Liu, Maria Shamin, Iva A. Tchasovnikarova, Richard T. Timms, Paul J. Lehner, Yorgo Modis
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Microrchidia CW-type zinc finger protein 2 (MORC2) is an effector of epigenetic silencing by the human silencing hub (HUSH). Here the authors present the crystal structures of MORC2 and disease-causing MORC2 mutants and give mechanistic insights into
Externí odkaz:
https://doaj.org/article/7fb05d6f62c94a08a8f144e58ba79a09
Publikováno v:
Wellcome Open Research, Vol 4 (2019)
Background: Lipid antigens are presented on the surface of cells by the CD1 family of glycoproteins, which have structural and functional similarity to MHC class I molecules. The hydrophobic lipid antigens are embedded in membranes and inaccessible t
Externí odkaz:
https://doaj.org/article/f5b005feeca54f919e89df3b5c11e7de
Autor:
Iain M. Hay, Maria Shamin, Eve R. Caroe, Ahmed S. A. Mohammed, Dmitri I. Svergun, Cy M. Jeffries, Stephen C. Graham, Hayley J. Sharpe, Janet E. Deane
Publikováno v:
The journal of biological chemistry 299(1), 102750 (2023). doi:10.1016/j.jbc.2022.102750
The journal of biological chemistry 299(1), 102750 (2023). doi:10.1016/j.jbc.2022.102750
Type IIB receptor protein tyrosine phosphatases are cell surface transmembrane proteins that engage in cell adhesion via their extracellular domains (ECDs)
Type IIB receptor protein tyrosine phosphatases are cell surface transmembrane proteins that engage in cell adhesion via their extracellular domains (ECDs)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e556fd20d8bf9090fa59b97c084d8d8
https://pubmed.ncbi.nlm.nih.gov/36436563
https://pubmed.ncbi.nlm.nih.gov/36436563
Autor:
Tomasz H. Benedyk, Viv Connor, Eve R. Caroe, Maria Shamin, Dmitri I. Svergun, Janet E. Deane, Cy M. Jeffries, Colin M. Crump, Stephen C. Graham
Herpes simplex virus (HSV)-1 dramatically alters the architecture and protein composition of cellular membranes during infection, but its effects upon membrane lipid composition remain unclear. HSV-1 pUL21 is a virus-encoded protein phosphatase adapt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48031de93e5af1694471afb490cd75bb
https://doi.org/10.1101/2022.06.01.494398
https://doi.org/10.1101/2022.06.01.494398
Autor:
Tomasz H. Benedyk, Viv Connor, Eve R. Caroe, Maria Shamin, Dmitri I. Svergun, Janet E. Deane, Cy M. Jeffries, Colin M. Crump, Stephen C. Graham
Publikováno v:
The journal of biological chemistry 298(11), 102589 (2022). doi:10.1016/j.jbc.2022.102589
JBC papers in press 298(11), 102589 (2022). doi:10.1016/j.jbc.2022.102589
Herpes simplex virus (HSV)-1 dramatically alters the architecture and protein composition of cellular membranes during infection, but its effects upon membrane lipid compo
Herpes simplex virus (HSV)-1 dramatically alters the architecture and protein composition of cellular membranes during infection, but its effects upon membrane lipid compo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1c1942d288af60d6bfbc0a3b0ebd06d
https://doi.org/10.1016/j.jbc.2022.102589
https://doi.org/10.1016/j.jbc.2022.102589
Publikováno v:
Wellcome Open Research
Background: Lipid antigens are presented on the surface of cells by the CD1 family of glycoproteins, which have structural and functional similarity to MHC class I molecules. The hydrophobic lipid antigens are embedded in membranes and inaccessible t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::899a31bea2e96fde97a8c375fdef4ca4
https://doi.org/10.1101/698654
https://doi.org/10.1101/698654
Autor:
Iva A. Tchasovnikarova, Maria Shamin, Paul J. Lehner, Richard T. Timms, Stuart Bloor, Yorgo Modis, Yangci Liu, Christopher H. Douse
Missense mutations in MORC2 cause neuropathies including spinal muscular atrophy and Charcot-Marie-Tooth disease. We recently identified MORC2 as an effector of epigenetic silencing by the HUSH complex. Here we report the biochemical and cellular act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ad28681900699f221a3a424915dc095