Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Maria Selmer"'
Autor:
Adrián González-López, Daniel S. D. Larsson, Ravi Kiran Koripella, Brett N. Cain, Martin Garcia Chavez, Paul J. Hergenrother, Suparna Sanyal, Maria Selmer
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract The antibiotic fusidic acid (FA) is used to treat Staphylococcus aureus infections. It inhibits protein synthesis by binding to elongation factor G (EF-G) and preventing its release from the ribosome after translocation. While FA, due to per
Externí odkaz:
https://doaj.org/article/688e7a88add545d890d90508e053347f
Autor:
Aleksandr Andriianov, Silvia Trigüis, Alena Drobiazko, Nicolas Sierro, Nikolai V. Ivanov, Maria Selmer, Konstantin Severinov, Artem Isaev
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112972- (2023)
Summary: Bacteriophage T3 encodes a SAMase that, through cleavage of S-adenosyl methionine (SAM), circumvents the SAM-dependent type I restriction-modification (R-M) defense. We show that SAMase also allows T3 to evade the BREX defense. Although SAM
Externí odkaz:
https://doaj.org/article/a2b2ebd74e704a3d81f06bcecb7623d6
Publikováno v:
Nordisk tidsskrift for utdanning og praksis, Vol 17, Iss 1 (2023)
Artikkelens hensikt er å bidra til økt innsikt i faktorer som har betydning for at barnehagen skal fungere som læringsarena for studenter ved arbeidsplassbasert barnehagelærerutdanning (ABLU). ABLU-studenter arbeider i barnehage parallelt med stu
Externí odkaz:
https://doaj.org/article/d57d8a3c81564ee385706c10bd20f0a8
Publikováno v:
Nordisk tidsskrift for utdanning og praksis, Vol 14, Iss 1, Pp 90-103 (2020)
Artikkelens hensikt er å bidra til økt innsikt i hvordan veiledning på egen arbeidsplass erfares av studenter på arbeidsplassbasert barnehagelærerutdanning. Barnehagen er en viktig læringsarena i studietiden, og veiledning i egen barnehage skal
Externí odkaz:
https://doaj.org/article/253f327938a649809f33842fe5f7cead
Publikováno v:
Biomolecules, Vol 12, Iss 11, p 1605 (2022)
Ribosomes are complex ribonucleoprotein particles. Purified 50S ribosomes subjected to high-salt wash, removing a subset of ribosomal proteins (r-proteins), were shown as competent for in vitro assembly into functional 50S subunits. Here, we used cry
Externí odkaz:
https://doaj.org/article/98100d211cf44661a8bbafde6374e904
Autor:
Xiaohu Guo, Annika Söderholm, Sandesh Kanchugal P, Geir V Isaksen, Omar Warsi, Ulrich Eckhard, Silvia Trigüis, Adolf Gogoll, Jon Jerlström-Hultqvist, Johan Åqvist, Dan I Andersson, Maria Selmer
Publikováno v:
eLife, Vol 10 (2021)
The first S-adenosyl methionine (SAM) degrading enzyme (SAMase) was discovered in bacteriophage T3, as a counter-defense against the bacterial restriction-modification system, and annotated as a SAM hydrolase forming 5’-methyl-thioadenosine (MTA) a
Externí odkaz:
https://doaj.org/article/525d1cf985e947098fe9b6f370a1c8f9
Autor:
Robert Gustafsson, Ulrich Eckhard, Weihua Ye, Erik D. Enbody, Mats Pettersson, Per Jemth, Leif Andersson, Maria Selmer
Publikováno v:
Biomolecules, Vol 10, Iss 12, p 1631 (2020)
Phosphoglucomutase 5 (PGM5) in humans is known as a structural muscle protein without enzymatic activity, but detailed understanding of its function is lacking. PGM5 belongs to the alpha-D-phosphohexomutase family and is closely related to the enzyma
Externí odkaz:
https://doaj.org/article/26c729e1ec4d4645a38548af8bcdd498
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97202 (2014)
Penicillin-binding proteins (PBPs) are enzymes responsible for the polymerization of the glycan strand and the cross-linking between glycan chains as well as the target proteins for β-lactam antibiotics. Mutational alterations in PBPs can confer res
Externí odkaz:
https://doaj.org/article/b9ea03bec44645c79322c48d6b332940
Autor:
Greta Hultqvist, Avinash S Punekar, Angela Morrone, Celestine N Chi, Ake Engström, Maria Selmer, Stefano Gianni, Per Jemth
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e50055 (2012)
Circular permutation is a common molecular mechanism for evolution of proteins. However, such re-arrangement of secondary structure connectivity may interfere with the folding mechanism causing accumulation of folding intermediates, which in turn can
Externí odkaz:
https://doaj.org/article/686f5d42279f47c3ae0bac20f3d94661
Autor:
Xiaohu Guo, Kristin Peisker, Kristina Bäckbro, Yang Chen, Ravi Kiran Koripella, Chandra Sekhar Mandava, Suparna Sanyal, Maria Selmer
Publikováno v:
Open Biology, Vol 2, Iss 3 (2012)
Fusidic acid (FA) is a bacteriostatic antibiotic that locks elongation factor G (EF-G) to the ribosome after GTP hydrolysis during elongation and ribosome recycling. The plasmid pUB101-encoded protein FusB causes FA resistance in clinical isolates of
Externí odkaz:
https://doaj.org/article/433cc239a5c4416486661bd84da90e9f