Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Maria Scarselli"'
Autor:
Samuele Irudal, Viola Camilla Scoffone, Gabriele Trespidi, Giulia Barbieri, Maura D’Amato, Simona Viglio, Mariagrazia Pizza, Maria Scarselli, Giovanna Riccardi, Silvia Buroni
Publikováno v:
Vaccines, Vol 11, Iss 6, p 1039 (2023)
The Burkholderia cepacia complex comprises environmental and clinical Gram-negative bacteria that infect particularly debilitated people, such as those with cystic fibrosis. Their high level of antibiotic resistance makes empirical treatments often i
Externí odkaz:
https://doaj.org/article/7ed37ef3b48e40b0a07c7e039d81679e
Autor:
Renzo Alfini, Brunella Brunelli, Erika Bartolini, Martina Carducci, Enrico Luzzi, Francesca Ferlicca, Scilla Buccato, Barbara Galli, Paola Lo Surdo, Maria Scarselli, Giacomo Romagnoli, Elena Cartocci, Domenico Maione, Silvana Savino, Francesca Necchi, Isabel Delany, Francesca Micoli
Publikováno v:
Vaccines, Vol 10, Iss 8, p 1182 (2022)
GMMA are outer membrane vesicles (OMVs) released from Gram-negative bacteria genetically modified to enhance OMVs formation that have been shown to be optimal systems to enhance immunogenicity of protein antigens. Here, we selected Neisseria meningit
Externí odkaz:
https://doaj.org/article/2aa72adc7a634959a0bc2fa879e89805
Autor:
Irene Bianconi, Beatriz Alcalá-Franco, Maria Scarselli, Mattia Dalsass, Scilla Buccato, Annalisa Colaprico, Sara Marchi, Vega Masignani, Alessandra Bragonzi
Publikováno v:
Frontiers in Immunology, Vol 9 (2019)
High incidence, severity and increasing antibiotic resistance characterize Pseudomonas aeruginosa infections, highlighting the need for new therapeutic options. Vaccination strategies to prevent or limit P. aeruginosa infections represent a rational
Externí odkaz:
https://doaj.org/article/69869d3544124cfc8d39cdf3d182014f
Autor:
Maria R. Romano, Rosanna Leuzzi, Emilia Cappelletti, Marta Tontini, Alberto Nilo, Daniela Proietti, Francesco Berti, Paolo Costantino, Roberto Adamo, Maria Scarselli
Publikováno v:
Toxins, Vol 6, Iss 4, Pp 1385-1396 (2014)
Clostridium difficile is a Gram-positive bacterium and is the most commonly diagnosed cause of hospital-associated and antimicrobial-associated diarrhea. Despite the emergence of epidemic C. difficile strains having led to an increase in the incidenc
Externí odkaz:
https://doaj.org/article/a2d80394ce5e44cea83f7f5b6efa5e95
Targeted Amino Acid Substitutions Impair Streptolysin O Toxicity and Group A Streptococcus Virulence
Autor:
Emiliano Chiarot, Cristina Faralla, Nico Chiappini, Giovanna Tuscano, Fabiana Falugi, Gabriella Gambellini, Annarita Taddei, Sabrina Capo, Elena Cartocci, Daniele Veggi, Alessia Corrado, Simona Mangiavacchi, Simona Tavarini, Maria Scarselli, Robert Janulczyk, Guido Grandi, Immaculada Margarit, Giuliano Bensi
Publikováno v:
mBio, Vol 4, Iss 1 (2013)
ABSTRACT Streptolysin O is a potent pore-forming toxin produced by group A Streptococcus. The aims of the present study were to dissect the relative contributions of different structural domains of the protein to hemolytic activity, to obtain a detox
Externí odkaz:
https://doaj.org/article/bb3003ecff814c90b395fe26d22ddb65
Autor:
Valeria Cafardi, Massimiliano Biagini, Manuele Martinelli, Rosanna Leuzzi, Jeffrey T Rubino, Francesca Cantini, Nathalie Norais, Maria Scarselli, Davide Serruto, Meera Unnikrishnan
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e81306 (2013)
Clostridium difficile is a major cause of infectious diarrhea worldwide. Although the cell surface proteins are recognized to be important in clostridial pathogenesis, biological functions of only a few are known. Also, apart from the toxins, protein
Externí odkaz:
https://doaj.org/article/e50033621e1b4a3f838d828e1dd5730f
Autor:
Glen Spraggon, Eric Koesema, Maria Scarselli, Enrico Malito, Massimiliano Biagini, Nathalie Norais, Carla Emolo, Michèle Anne Barocchi, Fabiola Giusti, Markus Hilleringmann, Rino Rappuoli, Scott Lesley, Antonello Covacci, Vega Masignani, Ilaria Ferlenghi
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e10919 (2010)
Streptococcus pneumoniae, like many other Gram-positive bacteria, assembles long filamentous pili on their surface through which they adhere to host cells. Pneumococcal pili are formed by a backbone, consisting of the repetition of the major componen
Externí odkaz:
https://doaj.org/article/656e18f1b5f0498888c53c2618bd2079
Autor:
Danilo Donnarumma, Fabiola Giusti, Carine Ysebaert, Philippe Hermand, Nathalie Devos, Ilaria Ferlenghi, Immaculada Margarit, Silvia Rossi Paccani, Maria Scarselli, Nathalie Norais
Publikováno v:
Vaccine. 40:6520-6527
Moraxella catarrhalis is an important and common respiratory pathogen that can cause Otitis Media, Community Acquired Pneumonia, and has been associated with an increased risk of exacerbations in chronic obstructive pulmonary disease in adults, leadi
Autor:
Daniele Veggi, Lucia Dello Iacono, Enrico Malito, Giulietta Maruggi, Fabiola Giusti, Panchali Goswami, Werner Pansegrau, Sara Marchi, Sara Tomei, Enrico Luzzi, Matthew James Bottomley, Federico Fontani, Ilaria Ferlenghi, Maria Scarselli
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 7; Pages: 6183
The presentation of viral antigens on nanoparticles in multivalent arrays has emerged as a valuable technology for vaccines. On the nanoparticle surface, highly ordered, repetitive arrays of antigens can mimic their geometric arrangement on virion su
Autor:
Rossella Cuffaro, Sonia Nicchi, Serena Tondi, Isabel Delany, Paolo Cinelli, Benedetta Manca, Giacomo Vezzani, Giada Antonelli, Viola Viviani, Maria Scarselli, Luigia Cappelli, Francesca Schiavetti
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 4943, p 4943 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Traditional antimicrobial treatments consist of drugs which target different essential functions in pathogens. Nevertheless, bacteria continue to evolve new mechanisms to evade this drug-mediated killing with surprising speed on the deployment of eac