Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Maria S.K. Stoll"'
Autor:
Lara K. Abramowitz, John A. Hanover, Charles L. Hoppel, Elizabeth O. Akinbiyi, Jason A. Mears, Brianna L. Bauer, Chao-Pin Hsiao, Maria S.K. Stoll
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
O-GlcNAcylation is a prevalent form of glycosylation that regulates proteins within the cytosol, nucleus, and mitochondria. The O-GlcNAc modification can affect protein cellular localization, function, and signaling interactions. The specific impact
Autor:
William H. Smith, Mohamed R. Ali, Charles L. Hoppel, Sean H. Adams, Sudeepa Bhattacharyya, Maria S.K. Stoll, Paul E. Minkler
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 313:E690-E698
The period around bariatric surgery offers a unique opportunity to characterize metabolism responses to dynamic shifts in energy, gut function, and anesthesia. We analyzed plasma acylcarnitines in obese women ( n = 17) sampled in the overnight fasted
Publikováno v:
Journal of Chromatography B. :128-133
Tandem MS acylcarnitine "profiles" are extremely valuable. Although used appropriately in newborn screening programs to identify patients with possible diseases, their inadequate quantitative accuracy and lack of selectivity is problematic for confir
Publikováno v:
The journal of applied laboratory medicine. 2(3)
Background Although correctly used in expanded newborn screening programs to identify patients with possible diseases, flow-injection tandem mass spectrometry (MS/MS) acylcarnitine “profiles” are inadequate for standard clinical uses owing to the
Publikováno v:
Molecular genetics and metabolism. 120(4)
While selectively quantifying acylcarnitines in thousands of patient samples using UHPLC-MS/MS, we have occasionally observed unidentified branched-chain C8 acylcarnitines. Such observations are not possible using tandem MS methods, which generate ps
Autor:
Brian D. Hoit, Julie H. Rennison, Paul E. Minkler, Martin E. Young, Kalpana K. Patel, Isidore C. Okere, Amy B. Foster, Hisashi Fujioka, Margaret P. Chandler, Charles L. Hoppel, Maria S.K. Stoll, Hiral V. Patel, Tracy A. McElfresh
Publikováno v:
Cardiovascular Research. 79:331-340
Aims Heart failure is associated with decreased myocardial fatty acid oxidation capacity and has been likened to energy starvation. Increased fatty acid availability results in an induction of genes promoting fatty acid oxidation. The aim of the pres
Publikováno v:
Analytical chemistry. 87(17)
A validated quantitative method for the determination of free and total carnitine, butyrobetaine, and acylcarnitines is presented. The versatile method has four components: (1) isolation using strong cation-exchange solid-phase extraction, (2) deriva
Autor:
Thomas J. Slabe, Edward J. Lesnefsky, Bernard Tandler, Charles L. Hoppel, Paul E. Minkler, Medhat O. Hassan, Qun Chen, Maria S.K. Stoll
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 287:H258-H267
Ischemia and reperfusion result in mitochondrial dysfunction, with decreases in oxidative capacity, loss of cytochrome c, and generation of reactive oxygen species. During ischemia of the isolated perfused rabbit heart, subsarcolemmal mitochondria, l
Publikováno v:
Analytical Biochemistry. 285:246-254
We describe a comprehensive approach to the separation, quantitation, and characterization of phospholipids and lysophospholipids present in complex biological samples. The central feature is a normal-phase HPLC separation of individual phospholipid
Autor:
Maria S.K. Stoll, Paul E. Minkler, Henk van Lenthe, Sander M. Houten, Charles L. Hoppel, Wilhelm Stoffel, Jörn Oliver Sass, Ronald J.A. Wanders, K Otfried Schwab, Uwe Janssen, Wim Kulik, Heleen te Brinke, Michel van Weeghel
Publikováno v:
FASEB journal, 26(10), 4316-4326. FASEB
Mitochondrial enoyl-CoA isomerase (ECI1) is an auxiliary enzyme involved in unsaturated fatty acid oxidation. In contrast to most of the other enzymes involved in fatty acid oxidation, a deficiency of ECI1 has yet to be identified in humans. We used