Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Maria S. Legina"'
Autor:
Bernhard K. Keppler, Wolfgang Kandioller, Michael A. Jakupec, Leticia González, Maria S. Legina, Juan J. Nogueira
Publikováno v:
Journal of Biological Inorganic Chemistry
Topoisomerase IIα (topo2α) is an essential nuclear enzyme involved in DNA replication, transcription, recombination, chromosome condensation, and highly expressed in many tumors. Thus, topo2α-targeting has become a very efficient and well-establis
Autor:
Michael A. Jakupec, Jelena Poljarević, Wolfgang Kandioller, Bernhard K. Keppler, Éva A. Enyedy, Maria S. Legina, Alexander Roller, Heiko Geisler, János P. Mészáros, Michaela Hejl
Publikováno v:
Journal of Organometallic Chemistry
Half-sandwich organometallic complexes featuring Ru(II), Os(II) and Rh(III) metal centers and naturally occurring bidentate 2-hydroxy-[1,4]-naphthoquinone ligands (lawsone and phthiocol) have been synthesized and characterized in both solid state and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7ecd790c7bbd1d4f066ac2073ca52eb
http://cherry.chem.bg.ac.rs/handle/123456789/3804
http://cherry.chem.bg.ac.rs/handle/123456789/3804
Autor:
Alexander Roller, Verena Pichler, Melanie Schmidlehner, Carmen M. Hackl, Maria S. Legina, Wolfgang Kandioller, Orsolya Dömötör, Michael A. Jakupec, Éva A. Enyedy, Bernhard K. Keppler
Publikováno v:
Chemistry - A European Journal. 22:17269-17281
Thiomaltol, a potential S,O-coordinating molecule, has been utilized for the complexation of four different organometallic fragments, yielding the desired RuII , OsII , RhIII , and IrIII complexes having a "piano-stool" configuration. In addition to
Autor:
Christian G. Hartinger, Maria S. Legina, Samuel M. Meier-Menches, Cynthia Licona, Michael A. Jakupec, Sarah Theiner, Muhammad Hanif, Michaela Hejl, Martin Pfaffeneder-Kmen, Bernhard K. Keppler, Christophe Orvain, Maria V. Babak, Christian Gaiddon
Publikováno v:
Inorganic Chemistry
Inorganic Chemistry, American Chemical Society, 2018, 57 (5), pp.2851-2864. ⟨10.1021/acs.inorgchem.7b03210⟩
Inorganic Chemistry, 2018, 57 (5), pp.2851-2864. ⟨10.1021/acs.inorgchem.7b03210⟩
Inorganic Chemistry, American Chemical Society, 2018, 57 (5), pp.2851-2864. ⟨10.1021/acs.inorgchem.7b03210⟩
Inorganic Chemistry, 2018, 57 (5), pp.2851-2864. ⟨10.1021/acs.inorgchem.7b03210⟩
We thank Prof. Markus Galanski for providing Pt precursors.; International audience; Platinum-based anticancer coordination compounds are widely used in the treatment of many tumor types, where they are very effective but also cause severe side effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0dea6d18bea763c68583c9bbb48697a
https://www.hal.inserm.fr/inserm-02364163/file/acs.inorgchem.7b03210.pdf
https://www.hal.inserm.fr/inserm-02364163/file/acs.inorgchem.7b03210.pdf
Autor:
Helena Henke, Oliver Brüggemann, Michael A. Jakupec, Maria S. Legina, Bernhard K. Keppler, Beatrix Schoenhacker-Alte, Petra Heffeter, Matthias H. M. Klose, Walter Berger, Ian Teasdale, Wolfgang Kandioller, Carmen M. Hackl
Publikováno v:
Dalton transactions (Cambridge, England : 2003). 46(36)
Within this work we aimed to improve the pharmacodynamics and toxicity profile of organoruthenium and -rhodium complexes which had previously been found to be highly potent in vitro but showed unselective activity in vivo. Different organometallic co