Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Maria S. Kelly"'
Autor:
Evgenii Kliuchnikov, Eugene Klyshko, Maria S. Kelly, Artem Zhmurov, Ruxandra I. Dima, Kenneth A. Marx, Valeri Barsegov
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 953-974 (2022)
Microtubules (MTs), a cellular structure element, exhibit dynamic instability and can switch stochastically from growth to shortening; but the factors that trigger these processes at the molecular level are not understood. We developed a 3D Microtubu
Externí odkaz:
https://doaj.org/article/7559ac355a154cb78436a62351f9e059
Autor:
Rohith Anand Varikoti, Hewafonsekage Yasan Y. Fonseka, Maria S. Kelly, Alex Javidi, Mangesh Damre, Sarah Mullen, Jimmie L. Nugent, Christopher M. Gonzales, George Stan, Ruxandra I. Dima
Publikováno v:
Nanomaterials, Vol 12, Iss 11, p 1849 (2022)
Essential cellular processes of microtubule disassembly and protein degradation, which span lengths from tens of μm to nm, are mediated by specialized molecular machines with similar hexameric structure and function. Our molecular simulations at ato
Externí odkaz:
https://doaj.org/article/f1d5f658f89c4e70b62e69b016b0b8de
Autor:
Steven M. Quarin, Amanda C. Macke, Lyndsay N. Kissell, Maria S. Kelly, Ashan Dayananda, Joseph Ungvary, George Stan, Ruxandra I. Dima, Pietro Strobbia
Publikováno v:
ACS Sensors. 8:2000-2010
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b42f399068e74bcaae0c4c38c8381d5e
https://doi.org/10.1021/acssensors.3c00175
https://doi.org/10.1021/acssensors.3c00175
Autor:
Amanda C. Macke, Maria S. Kelly, Rohith Anand Varikoti, Sarah Mullen, Daniel Groves, Clare Forbes, Ruxandra I. Dima
Publikováno v:
The Journal of Physical Chemistry B. 126:10569-10586
Severing proteins are nanomachines from the AAA+ (ATPases associated with various cellular activities) superfamily whose function is to remodel the largest cellular filaments, microtubules. The standard AAA+ machines adopt hexameric ring structures f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1db0682d4f102d91180d5c7499b3343f
https://doi.org/10.1021/acs.jpcb.2c05288
https://doi.org/10.1021/acs.jpcb.2c05288
Autor:
Maria S. Kelly, Amanda C. Macke, Shehani Kahawatte, Jacob E. Stump, Abigail R. Miller, Ruxandra I. Dima
Publikováno v:
The Journal of Chemical Physics. 158:125102
The nanomachine from the ATPases associated with various cellular activities superfamily, called spastin, severs microtubules during cellular processes. To characterize the functionally important allostery in spastin, we employed methods from evoluti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c34da41e401fffc0d78d7e884aa0802a
https://doi.org/10.1063/5.0139273
https://doi.org/10.1063/5.0139273
Publikováno v:
Biophysical Journal. 121:116a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75e3b58de5d31993765b56a53b635f92
https://doi.org/10.1016/j.bpj.2021.11.2157
https://doi.org/10.1016/j.bpj.2021.11.2157