Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Maria Sällemark"'
Publikováno v:
Acta Pharmacologica et Toxicologica. 58:61-70
A number of potential neuroleptic drugs of the substituted benzamide type have been compared with some reference neuroleptic drugs regarding their affinities for rat brain receptors using in vitro receptor binding techniques. The effects on dopamine-
Autor:
Åsa Malmberg, Susanne Rosqvist, Nina Mohell, Thomas Högberg, Maria Sällemark, David M. Jackson
Publikováno v:
European Journal of Pharmacology. 238:121-125
The substituted benzamide, remoxipride, is a new atypical antipsychotic agent with good clinical efficacy and low extrapyramidal side-effect potential. In the present study, the in vitro receptor binding properties of remoxipride and several of its m
Publikováno v:
Acta Pharmacologica et Toxicologica. 47:159-160
Publikováno v:
Pharmacology & Toxicology. 63:118-121
The influence of temperature on the in vitro binding of 3H-raclopride to rat striatal dopamine-D2 receptors was investigated. The KD-values obtained in Scatchard plots were approximately 1.6 nM at temperatures between 15 degrees and 30 degrees. At 37
Publikováno v:
Acta pharmacologica et toxicologica. 54(5)
Using in vitro receptor binding techniques, the effects of a number of different antidepressants on rat cerebral cortex receptors were investigated. In contrast to the tricyclic antidepressants, which potently inhibit several postsynaptic receptors,
Publikováno v:
Journal of neural transmission. 59(1)
The dependence of intact noradrenergic and serotonergic nerve terminals for the decrease in the number of beta-adrenoceptors and 5-HT2 binding sites in the cerebral cortex produced by long-term treatment of rats with antidepressant drugs was examined
Autor:
Håkan Hall, Maria Sällemark
Publikováno v:
Pharmacologytoxicology. 60(5)
The effects of repeated oral administration to rats of three antipsychotic compounds (haloperidol 1 mumol/kg, raclopride 5 mumol/kg and remoxipride 10 mumol/kg) on agonist affinity states of the dopamine-D2 receptor were studied using 3H-spiperone bi