Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Maria Rosaria Battista"'
Autor:
Maria Rosaria Battista, Antonella Grigoletto, Tommaso Tedeschini, Antonella Cellucci, Fabrizio Colaceci, Ralph Laufer, Gianfranco Pasut, Annalise Di Marco
Publikováno v:
PLoS ONE, Vol 17, Iss 3 (2022)
Ciliary neurotrophic factor (CNTF) is a neurotrophic cytokine able to induce appetite reduction, weight loss and antidiabetic effects. However, its susceptibility to neutralizing anti-CNTF antibodies in patients hampered its use for treatment of huma
Externí odkaz:
https://doaj.org/article/275712289d7d46749feca52a20c48f5e
Autor:
Domenico Vignone, Odalys Gonzalez Paz, Ivan Fini, Antonella Cellucci, Giulio Auciello, Maria Rosaria Battista, Isabelle Gloaguen, Silvia Fortuni, Cristina Cariulo, Vinod Khetarpal, Celia Dominguez, Ignacio Muñoz-Sanjuán, Annalise Di Marco
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 14, p 7813 (2022)
While blood–brain barrier (BBB) dysfunction has been described in neurological disorders, including Huntington’s disease (HD), it is not known if endothelial cells themselves are functionally compromised when promoting BBB dysfunction. Furthermor
Externí odkaz:
https://doaj.org/article/270c5f78ddb04b92bb989dab36bd3230
Autor:
Annalise Di Marco, Domenico Vignone, Odalys Gonzalez Paz, Ivan Fini, Maria Rosaria Battista, Antonella Cellucci, Elena Bracacel, Giulio Auciello, Maria Veneziano, Vinod Khetarpal, Mark Rose, Alessandro Rosa, Isabelle Gloaguen, Edith Monteagudo, Todd Herbst, Celia Dominguez, Ignacio Muñoz-Sanjuán
Publikováno v:
Cells, Vol 9, Iss 4, p 994 (2020)
The blood-brain barrier (BBB) is responsible for the homeostasis between the cerebral vasculature and the brain and it has a key role in regulating the influx and efflux of substances, in healthy and diseased states. Stem cell technology offers the o
Externí odkaz:
https://doaj.org/article/d4344a862cc142e2914339bfced09308
Autor:
Maria Rosaria Battista, Rajhans Sharma, Yves Mély, Marisabella Santoriello, Edith Monteagudo, Paola Fezzardi, Eleonore Real, Maurizio Zazzi, Vincenzo Summa, Mattia Mori, Maria Chiara Dasso Lang, Steven J. Harper, Savina Malancona, Antonella Cellucci, Manuel Pires, Martina Nibbio, Maurizio Botta, Roberto Speziale, Andreina Basta, Nadia Gennari, Francesco Saladini, Davide De Forni, Annalise Di Marco, Alessia Giannini, Lesia Kovalenko
Publikováno v:
ACS Med Chem Lett
[Image: see text] The HIV-1 nucleocapsid (NC) protein is a small basic DNA and RNA binding protein that is absolutely necessary for viral replication and thus represents a target of great interest to develop new anti-HIV agents. Moreover, the highly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bca7f5ccee8b2fa882bee58c45c157f
https://doi.org/10.1021/acsmedchemlett.9b00608
https://doi.org/10.1021/acsmedchemlett.9b00608
Autor:
Maria Rosaria Battista, Antonella Grigoletto, Tommaso Tedeschini, Antonella Cellucci, Fabrizio Colaceci, Ralph Laufer, Gianfranco Pasut, Annalise Di Marco
Publikováno v:
PloS one. 17(3)
Ciliary neurotrophic factor (CNTF) is a neurotrophic cytokine able to induce appetite reduction, weight loss and antidiabetic effects. However, its susceptibility to neutralizing anti-CNTF antibodies in patients hampered its use for treatment of huma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18984018e339d77e1a28aa1365875f54
https://pubmed.ncbi.nlm.nih.gov/35316287
https://pubmed.ncbi.nlm.nih.gov/35316287
Autor:
Mark Rose, Odalys Gonzalez Paz, Giulio Auciello, Annalise Di Marco, Todd Herbst, Ignacio Muñoz-Sanjuán, Domenico Vignone, Edith Monteagudo, Vinod Khetarpal, Matteo Zini, Maria Rosaria Battista, Laura Orsatti, Vincenzo Summa, Celia Dominguez, Leticia M Toledo-Sherman, Ivan Fini, Antonella Cellucci
Publikováno v:
Molecular Pharmaceutics. 16:2069-2082
Huntington's disease (HD) is a neurodegenerative disease caused by polyglutamine expansion in the huntingtin protein. For drug candidates targeting HD, the ability to cross the blood-brain barrier (BBB) and reach the site of action in the central ner
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27cfdbc702df6685a64c4f15855675c2
https://doi.org/10.1021/acs.molpharmaceut.9b00042
https://doi.org/10.1021/acs.molpharmaceut.9b00042
Autor:
Roberto Cirilli, Daniela De Vita, Marcel Kaiser, Antonella Messore, Valentina Noemi Madia, Cristina Faggi, Claudia M. Calvet, Vincenzo Summa, Annalise Di Marco, Gareth K. Jennings, Larissa M. Podust, Alessandro De Leo, Roberta Costi, Roberto Di Santo, Luca Pescatori, Valeria Tudino, Pascal Mäser, Reto Brun, Francesco Saccoliti, Luigi Scipione, Giacomo Pepe, Maria Rosaria Battista
Publikováno v:
Journal of Medicinal Chemistry. 62:1330-1347
We have designed and synthesized a series of new imidazole-based compounds structurally related to an antiprotozoal agent with nanomolar activity which we identified recently. The new analogues possess micromolar activities against Trypanosoma brucei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b0d6a27ad3e05cf4a14503c55d2243e
https://doi.org/10.1021/acs.jmedchem.8b01464
https://doi.org/10.1021/acs.jmedchem.8b01464
Autor:
Ivan Fini, Maria Veneziano, Vinod Khetarpal, Elena Bracacel, Todd Herbst, Ignacio Munoz-Sanjuan, Mark Rose, Giulio Auciello, Edith Monteagudo, Alessandro Rosa, Celia Dominguez, Odalys Gonzalez Paz, Antonella Cellucci, Annalise Di Marco, Maria Rosaria Battista, Isabelle Gloaguen, Domenico Vignone
Publikováno v:
Cells
Volume 9
Issue 4
Cells, Vol 9, Iss 994, p 994 (2020)
Volume 9
Issue 4
Cells, Vol 9, Iss 994, p 994 (2020)
The blood-brain barrier (BBB) is responsible for the homeostasis between the cerebral vasculature and the brain and it has a key role in regulating the influx and efflux of substances, in healthy and diseased states. Stem cell technology offers the o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a041cf35a29cb7bd1fddf8e63e91991e
http://hdl.handle.net/11573/1387940
http://hdl.handle.net/11573/1387940
Autor:
Vignone, Domenico1 (AUTHOR) d.vignone@irbm.com, Gonzalez Paz, Odalys1 (AUTHOR) o.gonzalez@irbm.com, Fini, Ivan1 (AUTHOR) i.fini@irbm.com, Cellucci, Antonella1 (AUTHOR) a.cellucci@irbm.com, Auciello, Giulio1 (AUTHOR) g.auciello@irbm.com, Battista, Maria Rosaria1 (AUTHOR) m.battista@irbm.com, Gloaguen, Isabelle1 (AUTHOR) gloaguenisa@gmail.com, Fortuni, Silvia1 (AUTHOR) s.fortuni@irbm.com, Cariulo, Cristina1 (AUTHOR) c.cariulo@irbm.com, Khetarpal, Vinod2 (AUTHOR) vinod.khetarpal@chdifoundation.org, Dominguez, Celia2 (AUTHOR) celia.dominguez@chdifoundation.org, Muñoz-Sanjuán, Ignacio2 (AUTHOR) ignacio.munoz@chdifoundation.org, Di Marco, Annalise1 (AUTHOR) a.dimarco@irbm.com
Publikováno v:
International Journal of Molecular Sciences. Jul2022, Vol. 23 Issue 14, p7813-7813. 33p.
Efficacy of PEGylated ciliary neurotrophic factor superagonist variant in diet-induced obesity mice.
Autor:
Battista, Maria Rosaria1 (AUTHOR), Grigoletto, Antonella2 (AUTHOR), Tedeschini, Tommaso2 (AUTHOR), Cellucci, Antonella1 (AUTHOR), Colaceci, Fabrizio1 (AUTHOR), Laufer, Ralph3 (AUTHOR), Pasut, Gianfranco2 (AUTHOR) a.dimarco@irbm.com, Di Marco, Annalise1 (AUTHOR) a.dimarco@irbm.com
Publikováno v:
PLoS ONE. 3/22/2022, Vol. 17 Issue 3, p1-19. 19p.