Zobrazeno 1 - 10
of 553
pro vyhledávání: '"Maria Rita Passos Bueno"'
Autor:
Estevão Carlos Silva Barcelos, Michel Satya Naslavsky, Izadora Silveira Fernandes, Marilia Oliveira Scliar, Guilherme Lopes Yamamoto, Jaqueline Yu Ting Wang, Laís Bride, Valdemir Pereira de Sousa, Lucia Helena Sagrillo Pimassoni, Paolo Sportoletti, Flavia de Paula, Sandra Ventorin von Zeidler, Yeda Aparecida Oliveira Duarte, Maria Rita Passos-Bueno, Mayana Zatz, Flávia Imbroisi Valle Errera
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Excessive weight (overweight and obesity) is a common disorder involving genetic and environmental factors, associated with cardiovascular diseases, type-2 diabetes, and others. NOTCH1 is critical for the maintenance of stem cells and adult
Externí odkaz:
https://doaj.org/article/2fa406e763034efdb5b865ee2f956c05
Autor:
Nathalia Ferrazzo Naspolini, Pedro A. R. Vanzele, Pedro Tótolo, Paulo Alfonso Schüroff, Daniel Fatori, Santos Alves Vicentini Neto, Cristiane Barata-Silva, Lisia Maria Gobbo dos Santos, André Fujita, Maria Rita Passos-Bueno, Patricia C. B. Beltrão-Braga, Alline C. Campos, André C. P. L. F. Carvalho, Guilherme V. Polanczyk, Josino Costa Moreira, Carla R. Taddei
Publikováno v:
Frontiers in Public Health, Vol 12 (2024)
Infants growing up in low- and middle-income countries are at increased risk of suffering adverse childhood experiences, including exposure to environmental pollution and lack of cognitive stimulation. In this study, we aimed to examine the levels of
Externí odkaz:
https://doaj.org/article/28538d66443a47678d8bb97cb961b81c
Autor:
Ana Carla Batissoco, Dayane Bernardino Cruz, Thiago Geronimo Pires Alegria, Gerson Kobayashi, Jeanne Oiticica, Luis Eduardo Soares Netto, Maria Rita Passos-Bueno, Luciana Amaral Haddad, Regina Célia Mingroni Netto
Publikováno v:
Genetics and Molecular Biology, Vol 47, Iss 2 (2024)
Abstract Pathogenic DNA alterations in GJB2 are present in nearly half of non-syndromic hearing loss cases with autosomal recessive inheritance. The most frequent variant in GJB2 causing non-syndromic hearing loss is the frameshifting c.35del. GJB2 e
Externí odkaz:
https://doaj.org/article/c6713cfb621f46a69541e86a7eda7f3b
Autor:
Lucas Alvizi, Diogo Nani, Luciano Abreu Brito, Gerson Shigeru Kobayashi, Maria Rita Passos-Bueno, Roberto Mayor
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Gene–environment interactions are believed to play a role in multifactorial phenotypes, although poorly described mechanistically. Cleft lip/palate (CLP), the most common craniofacial malformation, has been associated with both genetic and
Externí odkaz:
https://doaj.org/article/36cad45c8b4c480c9d01f3a2abc79137
Autor:
Lucas Alvizi, Luciano Abreu Brito, Gerson Shigeru Kobayashi, Bárbara Bischain, Camila Bassi Fernandes da Silva, Sofia Ligia Guimaraes Ramos, Jaqueline Wang, Maria Rita Passos-Bueno
Publikováno v:
Epigenetics, Vol 17, Iss 13, Pp 2278-2295 (2022)
Non-syndromic cleft lip with or without cleft palate (NSCLP), the most common human craniofacial malformation, is a complex disorder given its genetic heterogeneity and multifactorial component revealed by genetic, epidemiological, and epigenetic fin
Externí odkaz:
https://doaj.org/article/373da2f176254d3ca92182598dfd9fe0
Autor:
Mateus V. de Castro, Monize V. R. Silva, Michel S. Naslavsky, Marilia O. Scliar, Kelly Nunes, Maria Rita Passos-Bueno, Erick C. Castelli, Jhosiene Y. Magawa, Flávia L. Adami, Ana I. S. Moretti, Vivian L. de Oliveira, Silvia B. Boscardin, Edecio Cunha-Neto, Jorge Kalil, Emmanuelle Jouanguy, Paul Bastard, Jean-Laurent Casanova, Mauricio Quiñones-Vega, Patricia Sosa-Acosta, Jéssica S. de Guedes, Natália P. de Almeida, Fábio C. S. Nogueira, Gilberto B. Domont, Keity S. Santos, Mayana Zatz
Publikováno v:
Immunity & Ageing, Vol 19, Iss 1, Pp 1-9 (2022)
Abstract Background Although older adults are at a high risk of severe or critical Covid-19, there are many cases of unvaccinated centenarians who had a silent infection or recovered from mild or moderate Covid-19. We studied three Brazilian supercen
Externí odkaz:
https://doaj.org/article/6de9bfd0b0e44612be7ded415f3c9515
Autor:
André Luíz Teles e Silva, Talita Glaser, Karina Griesi-Oliveira, Juliana Corrêa-Velloso, Jaqueline Yu Ting Wang, Gabriele da Silva Campos, Henning Ulrich, Andrea Balan, Mehdi Zarrei, Edward J. Higginbotham, Stephen W. Scherer, Maria Rita Passos-Bueno, Andrea Laurato Sertié
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Oligogenic inheritance of autism spectrum disorder (ASD) has been supported by several studies. However, little is known about how the risk variants interact and converge on causative neurobiological pathways. We identified in an ASD proband
Externí odkaz:
https://doaj.org/article/255dbd3df2934e7f9fac9cc1a130486a
Autor:
Michel S. Naslavsky, Marilia O. Scliar, Guilherme L. Yamamoto, Jaqueline Yu Ting Wang, Stepanka Zverinova, Tatiana Karp, Kelly Nunes, José Ricardo Magliocco Ceroni, Diego Lima de Carvalho, Carlos Eduardo da Silva Simões, Daniel Bozoklian, Ricardo Nonaka, Nayane dos Santos Brito Silva, Andreia da Silva Souza, Heloísa de Souza Andrade, Marília Rodrigues Silva Passos, Camila Ferreira Bannwart Castro, Celso T. Mendes-Junior, Rafael L. V. Mercuri, Thiago L. A. Miller, Jose Leonel Buzzo, Fernanda O. Rego, Nathalia M. Araújo, Wagner C. S. Magalhães, Regina Célia Mingroni-Netto, Victor Borda, Heinner Guio, Carlos P. Rojas, Cesar Sanchez, Omar Caceres, Michael Dean, Mauricio L. Barreto, Maria Fernanda Lima-Costa, Bernardo L. Horta, Eduardo Tarazona-Santos, Diogo Meyer, Pedro A. F. Galante, Victor Guryev, Erick C. Castelli, Yeda A. O. Duarte, Maria Rita Passos-Bueno, Mayana Zatz
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Whole genome sequencing (WGS) data on non-European and admixed individuals remains scarce. Here, the authors analyse WGS data from 1,171 admixed elderly Brazilians from a census cohort, characterising population-specific genetic variation and explori
Externí odkaz:
https://doaj.org/article/363cefb9d1d14e1f9adc1fe81f04cd3f
Autor:
Erick C. Castelli, Bibiana S. de Almeida, Yara C. N. Muniz, Nayane S. B. Silva, Marília R. S. Passos, Andreia S. Souza, Abigail E. Page, Mark Dyble, Daniel Smith, Gabriela Aguileta, Jaume Bertranpetit, Andrea B. Migliano, Yeda A. O. Duarte, Marília O. Scliar, Jaqueline Wang, Maria Rita Passos-Bueno, Michel S. Naslavsky, Mayana Zatz, Celso Teixeira Mendes-Junior, Eduardo A. Donadi
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract HLA-G is a promiscuous immune checkpoint molecule. The HLA-G gene presents substantial nucleotide variability in its regulatory regions. However, it encodes a limited number of proteins compared to classical HLA class I genes. We characteriz
Externí odkaz:
https://doaj.org/article/4aa35f18b2a3467d92010afb84f174e1
Autor:
Erick C. Castelli, Mateus V. de Castro, Michel S. Naslavsky, Marilia O. Scliar, Nayane S. B. Silva, Raphaela N. Pereira, Viviane A. O. Ciriaco, Camila F. B. Castro, Celso T. Mendes-Junior, Etiele de S. Silveira, Iuri M. de Oliveira, Eduardo C. Antonio, Gustavo F. Vieira, Diogo Meyer, Kelly Nunes, Larissa R. B. Matos, Monize V. R. Silva, Jaqueline Y. T. Wang, Joyce Esposito, Vivian R. Cória, Jhosiene Y. Magawa, Keity S. Santos, Edecio Cunha-Neto, Jorge Kalil, Raul H. Bortolin, Mário Hiroyuki Hirata, Luiz P. Dell’Aquila, Alvaro Razuk-Filho, Pedro B. Batista-Júnior, Amaro N. Duarte-Neto, Marisa Dolhnikoff, Paulo H. N. Saldiva, Maria Rita Passos-Bueno, Mayana Zatz
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundAlthough aging correlates with a worse prognosis for Covid-19, super elderly still unvaccinated individuals presenting mild or no symptoms have been reported worldwide. Most of the reported genetic variants responsible for increased disease
Externí odkaz:
https://doaj.org/article/2e2117d94dbe4d5a98250112d4b97251