Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Maria Ringvall"'
Autor:
Ananya Roy, Julia Femel, Elisabeth J M Huijbers, Dorothe Spillmann, Erik Larsson, Maria Ringvall, Anna-Karin Olsson, Magnus Åbrink
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0156151 (2016)
In hematopoietic cells, serglycin proteoglycans mainly contribute to proper storage and secretion of inflammatory mediators via their negatively charged glycosaminoglycans. Serglycin proteoglycans are also expressed in cancer cells where increased ex
Externí odkaz:
https://doaj.org/article/7c1f3e244d45449dac276f904e02108d
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0126688 (2015)
The serglycin proteoglycan is mainly expressed by hematopoietic cells where the major function is to retain the content of storage granules and vesicles. In recent years, expression of serglycin has also been found in different forms of human maligna
Externí odkaz:
https://doaj.org/article/11443a83bd524cf0a90f7898cb9e726a
Autor:
Maria Ringvall, Åsa Thulin, Lei Zhang, Jessica Cedervall, Nobuko Tsuchida-Straeten, Willi Jahnen-Dechent, Agneta Siegbahn, Anna-Karin Olsson
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e14526 (2011)
BACKGROUND: The heparin-binding plasma protein histidine-rich glycoprotein (HRG; alternatively, HRGP/HPRG) can suppress tumor angiogenesis and growth in vitro and in vivo. Mice lacking the HRG gene are viable and fertile, but have an enhanced coagula
Externí odkaz:
https://doaj.org/article/7509647b676e41e2a205a0a5cdab37b7
Autor:
Anna-Karin Olsson, Agneta Siegbahn, Wilhelm Jahnen-Dechent, Kristian Pietras, Helena Åkerud, Taina Pihlajaniemi, Bo Nilsson, Rolf Bjerkvig, Jian Wang, Osama Hamad, Marja-Riitta Väisänen, Timo Väisänen, Karin Kårehed, Anna Dimberg, Maria Ringvall, Åsa Thulin
Supplementary Data from Activated Platelets Provide a Functional Microenvironment for the Antiangiogenic Fragment of Histidine-Rich Glycoprotein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d87c769383fcce807bd85703a55f0ae
https://doi.org/10.1158/1541-7786.22518526.v1
https://doi.org/10.1158/1541-7786.22518526.v1
Autor:
Anna-Karin Olsson, Agneta Siegbahn, Wilhelm Jahnen-Dechent, Kristian Pietras, Helena Åkerud, Taina Pihlajaniemi, Bo Nilsson, Rolf Bjerkvig, Jian Wang, Osama Hamad, Marja-Riitta Väisänen, Timo Väisänen, Karin Kårehed, Anna Dimberg, Maria Ringvall, Åsa Thulin
The angiogenesis inhibitor histidine-rich glycoprotein (HRG) constitutes one of several examples of molecules regulating both angiogenesis and hemostasis. The antiangiogenic properties of HRG are mediated via its proteolytically released histidine- a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bbf8e7b112447a46564499c3b983e16
https://doi.org/10.1158/1541-7786.c.6541972.v1
https://doi.org/10.1158/1541-7786.c.6541972.v1
Autor:
Willi Jahnen-Dechent, Maria Ringvall, Yanyu Zhang, Anna-Karin Olsson, Jessica Cedervall, Aristidis Moustakas, Agneta Siegbahn, Åsa Thulin
Publikováno v:
Angiogenesis. 16:889-902
Mice lacking histidine-rich glycoprotein (HRG) display an accelerated angiogenic switch and larger tumors-a phenotype caused by enhanced platelet activation in the HRG-deficient mice. Here we show that platelets induce molecular changes in the pre-tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::def9a7c9c03e7fadc3ddd51025d3e575
https://doi.org/10.1007/s10456-013-9363-8
https://doi.org/10.1007/s10456-013-9363-8
Publikováno v:
The Journal of Immunology. 183:7073-7083
Serglycin (SG) proteoglycan consists of a small core protein to which glycosaminoglycans of chondroitin sulfate or heparin type are attached. SG is crucial for maintaining mast cell (MC) granule homeostasis through promoting the storage of various ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d2a1ade5229ee8e3b67f3c034868bd0
https://doi.org/10.4049/jimmunol.0900309
https://doi.org/10.4049/jimmunol.0900309
Publikováno v:
Molecular Immunology. 46:422-428
Mast cell granule maturation and storage of granule components has previously been shown to be critically dependent on serglycin (SG), a proteoglycan abundantly stored in mast cell secretory granules. The N-terminal portion of serglycin contains a co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa75cb5b0fa700dbe3548e51014c2803
https://doi.org/10.1016/j.molimm.2008.10.019
https://doi.org/10.1016/j.molimm.2008.10.019
Autor:
Gianni García-Faroldi, Gunnar Pejler, Sara Wernersson, Frida Henningsson, Elin Rönnberg, Ignacio Fajardo, Annette Duelli, Maria Ringvall, Magnus Åbrink
Publikováno v:
Journal of Allergy and Clinical Immunology. 121:1020-1026
Background Serotonin and histamine are components of human and rodent mast cell secretory granules. Objective Serotonin and histamine are stored in the same compartment as serglycin proteoglycan. Here we addressed the possibility that serglycin may b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f33754e644c6c746100197146052d54
https://doi.org/10.1016/j.jaci.2007.11.031
https://doi.org/10.1016/j.jaci.2007.11.031
Autor:
Holger Gerhardt, Alexandra Abramsson, Jin-Ping Li, Ulf Lindahl, Christer Betsholtz, Johan Ledin, Sindhulakshmi Kurup, Maria Ringvall, Göran Bondjers, Lena Kjellén, Dominique Sauvaget, Ulf Landegren, Shuhei Yamada, Marta Busse, Edith Schallmeiner, Per Lindblom, Denise Stenzel, Dorothe Spillmann
Publikováno v:
Genes & Development. 21:316-331
During vascular development, endothelial platelet-derived growth factor B (PDGF-B) is critical for pericyte recruitment. Deletion of the conserved C-terminal heparin-binding motif impairs PDGF-BB retention and pericyte recruitment in vivo, suggesting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc9304c5da8ae78fdab7fd27773778ab
https://doi.org/10.1101/gad.398207
https://doi.org/10.1101/gad.398207