Zobrazeno 1 - 10
of 174
pro vyhledávání: '"Maria Reig"'
Autor:
Sturla Magnus Grøndal, Anna Tutusaus, Loreto Boix, Maria Reig, Magnus Blø, Linn Hodneland, Gro Gausdal, Akil Jackson, Pablo Garcia de Frutos, James Bradley Lorens, Albert Morales, Montserrat Marí
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Background and aimsMetabolic dysfunction-associated steatohepatitis (MASH) is a significant health concern with limited treatment options. AXL, a receptor tyrosine kinase activated by the GAS6 ligand, promotes MASH through activation of hepatic stell
Externí odkaz:
https://doaj.org/article/6052153a12c545f1be1327af8224916c
Autor:
Julien Calderaro, Narmin Ghaffari Laleh, Qinghe Zeng, Pascale Maille, Loetitia Favre, Anaïs Pujals, Christophe Klein, Céline Bazille, Lara R. Heij, Arnaud Uguen, Tom Luedde, Luca Di Tommaso, Aurélie Beaufrère, Augustin Chatain, Delphine Gastineau, Cong Trung Nguyen, Hiep Nguyen-Canh, Khuyen Nguyen Thi, Viviane Gnemmi, Rondell P. Graham, Frédéric Charlotte, Dominique Wendum, Mukul Vij, Daniela S. Allende, Federico Aucejo, Alba Diaz, Benjamin Rivière, Astrid Herrero, Katja Evert, Diego Francesco Calvisi, Jérémy Augustin, Wei Qiang Leow, Howard Ho Wai Leung, Emmanuel Boleslawski, Mohamed Rela, Arnaud François, Anthony Wing-Hung Cha, Alejandro Forner, Maria Reig, Manon Allaire, Olivier Scatton, Denis Chatelain, Camille Boulagnon-Rombi, Nathalie Sturm, Benjamin Menahem, Eric Frouin, David Tougeron, Christophe Tournigand, Emmanuelle Kempf, Haeryoung Kim, Massih Ningarhari, Sophie Michalak-Provost, Purva Gopal, Raffaele Brustia, Eric Vibert, Kornelius Schulze, Darius F. Rüther, Sören A. Weidemann, Rami Rhaiem, Jean-Michel Pawlotsky, Xuchen Zhang, Alain Luciani, Sébastien Mulé, Alexis Laurent, Giuliana Amaddeo, Hélène Regnault, Eleonora De Martin, Christine Sempoux, Pooja Navale, Maria Westerhoff, Regina Cheuk-Lam Lo, Jan Bednarsch, Annette Gouw, Catherine Guettier, Marie Lequoy, Kenichi Harada, Pimsiri Sripongpun, Poowadon Wetwittayaklang, Nicolas Loménie, Jarukit Tantipisit, Apichat Kaewdech, Jeanne Shen, Valérie Paradis, Stefano Caruso, Jakob Nikolas Kather
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract Primary liver cancer arises either from hepatocytic or biliary lineage cells, giving rise to hepatocellular carcinoma (HCC) or intrahepatic cholangiocarcinoma (ICCA). Combined hepatocellular- cholangiocarcinomas (cHCC-CCA) exhibit equivocal
Externí odkaz:
https://doaj.org/article/ba65186be9624b389ea48c3c89596cfd
Autor:
Sara Ortiz-Rivero, Ana Peleteiro-Vigil, Lorena Abete, Elisa Lozano, Helen S. Hammer, Silvia Di Giacomo, Mar Abad, Loreto Boix, Alejandro Forner, Maria Reig, Rocio I.R. Macias, Oliver Pötz, Jose J.G. Marin, Oscar Briz
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 170, Iss , Pp 116038- (2024)
Cholangiocarcinomas (CCAs) are cancers originated in the biliary tree, which are characterized by their high mortality and marked chemoresistance, partly due to the activity of ATP-binding cassette (ABC) export pumps, whose inhibition has been propos
Externí odkaz:
https://doaj.org/article/b4843168fecc49a9b5509ab1be898085
Autor:
Irene Portolés, Jordi Ribera, Esther Fernandez-Galán, Elena Lecue, Gregori Casals, Pedro Melgar-Lesmes, Guillermo Fernández-Varo, Loreto Boix, Marco Sanduzzi, Veenu Aishwarya, Maria Reig, Wladimiro Jiménez, Manuel Morales-Ruiz
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 7, p 3716 (2024)
RNA helicase DHX15 plays a significant role in vasculature development and lung metastasis in vertebrates. In addition, several studies have demonstrated the overexpression of DHX15 in the context of hepatocellular carcinoma. Therefore, we hypothesiz
Externí odkaz:
https://doaj.org/article/b5b65b45f4fa4f94859aad6c338bdcb9
Autor:
Angeles Garcia-Criado, Jordi Rimola, Susana Seijo, Anna Darnell, Ernest Belmonte, Victor Sapena, Julián Moreno-Rojas, Valeria Pérez, Virginia Hernández-Gea, Carmen Ayuso, Maria Reig, Juan Carlos Garcia-Pagan, Jordi Bruix
Publikováno v:
Liver Cancer (2023)
Introduction The incidence of hepatocellular carcinoma (HCC) in Budd-Chiari syndrome (BCS) is unknown and there is no validated diagnostic work-up to define the liver nodules with arterial phase hyperenhancement (APHE) suggesting malignancy. This pro
Externí odkaz:
https://doaj.org/article/813f99e541e045f9a8aa41600680637f
Autor:
Manuela Eicher, Sanna Iivanainen, Maria Reig, Amparo Yovanna Castro Sanchez, Anne-Marie Baird, Bogdana Balas, Alberto Bustillos, Sophie Golding, Mathis Mueller-Ohldach, Manfred Welslau, Johannes Ammann
Publikováno v:
BMJ Open, Vol 13, Iss 4 (2023)
Introduction Digital patient monitoring (DPM) tools can enable more effective clinical care and improved patient outcomes in cancer. However, their broad adoption requires ease of use and demonstration of real-world clinical utility/impact. ORIGAMA (
Externí odkaz:
https://doaj.org/article/d84f45f54c0149dcaaf9cd6c718b2e56
Autor:
Giuseppe Cabibbo, Maria Reig, Ciro Celsa, Ferran Torres, Salvatore Battaglia, Marco Enea, Giacomo Emanuele Maria Rizzo, Salvatore Petta, Vincenza Calvaruso, Vito Di Marco, Antonio Craxì, Amit G. Singal, Jordi Bruix, Calogero Cammà
Publikováno v:
Liver Cancer, Pp 1-10 (2021)
Introduction: Atezolizumab (ATEZO) plus bevacizumab (BEVA) represents the new standard of care for the treatment of advanced hepatocellular carcinoma (HCC). However, the choice of the second-line treatment after the failure of immunotherapy-based fir
Externí odkaz:
https://doaj.org/article/49f9c3951aad466793506f22ced773ef
Autor:
Bruno Sangro, Maria Reig, Carlos Gómez-Martin, Josepmaria Argemi, Mercedes Iñarrairaegui, Laura Marquez, Manuel de la Torre-Aláez, Ana Matilla, Maria Varela, Jose Luis Lledó, Juan Ignacio Arenas, Sara Lorente, Milagros Testillano, Leonardo Da Fonseca, Macarena Rodriguez-Fraile, Jose I Bilbao
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 11 (2022)
Purpose To evaluate the safety and efficacy of selective internal radiation therapy (SIRT) in combination with a PD-1 inhibitor in patients with unresectable hepatocellular carcinoma (uHCC) and liver-only disease ineligible for chemoembolization.Pati
Externí odkaz:
https://doaj.org/article/e79ce69697db40a1966c37c1077aa4d6
Autor:
Anna Soria, Mariona Calvo, Meritxell Casas, Zara Vidales, Sergio Muñoz-Martínez, Victor Sapena, Marc Puigvehi, Lidia Canillas, Raquel Guardeño, Adolfo Gallego, Beatriz Mínguez, Diana Horta, Ariadna Clos, Silvia Montoliu, Mercè Roget, Maria Reig, Mercedes Vergara
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
IntroductionThe first-line treatment for advanced hepatocellular carcinoma (HCC) is atezolizumab plus bevacizumab, but its availability is not universal and elderly patients are underrepresented in clinical trials. There is little evidence of efficac
Externí odkaz:
https://doaj.org/article/ee56ec9457554833bfaf62de8c746951
Autor:
Pablo Fernández-Tussy, Rubén Rodríguez-Agudo, David Fernández-Ramos, Lucía Barbier-Torres, Imanol Zubiete-Franco, Sergio López de Davalillo, Elisa Herraez, Naroa Goikoetxea-Usandizaga, Sofia Lachiondo-Ortega, Jorge Simón, Fernando Lopitz-Otsoa, Virginia Gutiérrez-de Juan, Misti V. McCain, Maria J. Perugorria, Jon Mabe, Nicolás Navasa, Cecilia M. P. Rodrigues, Isabel Fabregat, Loreto Boix, Victor Sapena, Juan Anguita, Shelly C. Lu, José M. Mato, Jesus M. Banales, Erica Villa, Helen L. Reeves, Jordi Bruix, Maria Reig, Jose J. G. Marin, Teresa C. Delgado, María L. Martínez-Chantar
Publikováno v:
Cell Death and Disease, Vol 12, Iss 6, Pp 1-16 (2021)
Abstract Dysregulation of miRNAs is a hallmark of cancer, modulating oncogenes, tumor suppressors, and drug responsiveness. The multi-kinase inhibitor sorafenib is one of the first-line drugs for advanced hepatocellular carcinoma (HCC), although the
Externí odkaz:
https://doaj.org/article/fb7ef154614446039d3b36ccb14472c8