Sequence-Based Genotyping of Expressed Swine Leukocyte Antigen Class I Alleles by Next-Generation Sequencing Reveal Novel Swine Leukocyte Antigen Class I Haplotypes and Alleles in Belgian, Danish, and Kenyan Fattening Pigs and Göttingen Minipigs

Autor: Maria Rathmann Sørensen, Mette Ilsøe, Mikael Lenz Strube, Richard Bishop, Gitte Erbs, Sofie Bruun Hartmann, Gregers Jungersen

Publikováno v: Frontiers in Immunology, Vol 8 (2017)

The need for typing of the swine leukocyte antigen (SLA) is increasing with the expanded use of pigs as models for human diseases and organ-transplantation experiments, their use in infection studies, and for design of veterinary vaccines. Knowledge

Externí odkaz: https://doaj.org/article/aec86c149a8c4ccb9e050b51475b12ae

Predictable modulation of cancer treatment outcomes by the gut microbiota

Autor: Lejla Imamovic, Aimin Xu, Glen J. Weiss, Yueqiong Ni, Scott Quainoo, Yoshitaro Heshiki, Jun Li, Maria Rathmann Sørensen, Morten Otto Alexander Sommer, Jin Li, Ruben Vazquez-Uribe, Billy K. C. Chow, Gianni Panagiotou

Publikováno v: Microbiome, Vol 8, Iss 1, Pp 1-14 (2020)
Microbiome
Heshiki, Y, Vazquez-Uribe, R, Li, J, Ni, Y, Quainoo, S, Imamovic, L, Li, J, Sørensen, M, Chow, B K C, Weiss, G J, Xu, A, Sommer, M O A & Panagiotou, G 2020, ' Predictable modulation of cancer treatment outcomes by the gut microbiota ', Microbiome, vol. 8, no. 1, 28 . https://doi.org/10.1186/s40168-020-00811-2

The gut microbiota has the potential to influence the efficacy of cancer therapy. Here, we investigated the contribution of the intestinal microbiome on treatment outcomes in a heterogeneous cohort that included multiple cancer types to identify micr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d49631b45628abde5c40a2b792c3e8bd
http://link.springer.com/article/10.1186/s40168-020-00811-2

Sequence-Based Genotyping of Expressed Swine Leukocyte Antigen Class I Alleles by Next-Generation Sequencing Reveal Novel Swine Leukocyte Antigen Class I Haplotypes and Alleles in Belgian, Danish, and Kenyan Fattening Pigs and Göttingen Minipigs

Autor: Mikael Lenz Strube, Richard P. Bishop, Sofie Bruun Hartmann, Gitte Erbs, Maria Rathmann Sørensen, Gregers Jungersen, Mette Ilsøe

Publikováno v: Frontiers in Immunology, Vol 8 (2017)
Frontiers in Immunology
Sørensen, M R, Ilsøe, M, Strube, M L, Bishop, R, Erbs, G, Hartmann, S B & Jungersen, G 2017, ' Sequence-Based Genotyping of Expressed Swine Leukocyte Antigen Class I Alleles by Next-Generation Sequencing Reveal Novel Swine Leukocyte Antigen Class I Haplotypes and Alleles in Belgian, Danish, and Kenyan Fattening Pigs and Göttingen Minipigs ', Frontiers in Immunology, vol. 8, 701 . https://doi.org/10.3389/fimmu.2017.00701

The need for typing of the swine leukocyte antigen (SLA) is increasing with the expanded use of pigs as models for human diseases and organ-transplantation experiments, their use in infection studies, and for design of veterinary vaccines. Knowledge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3996fddf9db86d0e33239d3c56460bb6
http://journal.frontiersin.org/article/10.3389/fimmu.2017.00701/full

Improved Culture Medium (TiKa) for Mycobacterium avium Subspecies Paratuberculosis (MAP) Matches qPCR Sensitivity and Reveals Significant Proportions of Non-viable MAP in Lymphoid Tissue of Vaccinated MAP Challenged Animals

Autor: Tim J. Bull, Sofie Bruun Hartmann, Paula Matilde Lopez-Perez, Gregers Jungersen, Joanna S. Garcia, Tulika Munshi, Kai Hilpert, Sven Hofmann, Maria Rathmann Sørensen, Heidi Mikkelsen

Publikováno v: Bull, T J, Munshil, T, Melvang, H M, Hartmann, S B, Sørensen, M R, Garcia, J S, Lopez-Perez, P M, Hofmann, S, Hapert, K & Jungersen, G 2017, ' Improved Culture Medium (TiKa) for Mycobacterium avium Subspecies Paratuberculosis (MAP) Matches qPCR Sensitivity and Reveals Significant Proportions of Non-viable MAP in Lymphoid Tissue of Vaccinated MAP Challenged Animals ', Frontiers in Microbiology, vol. 7, 2112 . https://doi.org/10.3389/fmicb.2016.02112
Frontiers in Microbiology

The quantitative detection of viable pathogen load is an important tool in determining the degree of infection in animals and contamination of foodstuffs. Current conventional culture methods are limited in their ability to determine these levels in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd04776d6cefe5f3c0e190a350b98455
https://orbit.dtu.dk/en/publications/3d5e803b-18bb-48f6-b460-0aa9f574fcf5

Tracking the elusive cytotoxic T cell response in pigs

Autor: Gregers Jungersen, Morten Nielsen, Nana Haahr Overgaard, Thomas Mørch Frøsig, Maria Rathmann Sørensen, Simon Welner, Mikael Lenz Strube, Lasse Eggers Pedersen, Ole Lund, Golde, William T., Søren Buus

Publikováno v: Jungersen, G, Nielsen, M, Overgaard, N H, Frøsig, T M, Sørensen, M R, Welner, S, Strube, M L, Pedersen, L E, Lund, O, Golde, W T & Buus, S 2016, ' Tracking the elusive cytotoxic T cell response in pigs ' 11th International Veterinary Immunology Symposium, Gold Coast, Australia, 16/08/2016-19/08/2016, .
Technical University of Denmark Orbit

Quantitative and qualitative assessment of antigen-specific cytotoxic T cell (CTL) responses in pigs is not a straightforward process. Through the years we have developed a series of reagents, tools and protocols to characterize peptide-specific CTL

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::25517b208c38cbe40403ecdbac68ea50
http://orbit.dtu.dk/en/publications/tracking-the-elusive-cytotoxic-t-cell-response-in-pigs(a755e4e8-0ed3-4032-9b51-fbc319ac9329).html