Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Maria Ramos Zapatero"'
Autor:
Joe R Delaney, Chandni B Patel, Jaidev Bapat, Christian M Jones, Maria Ramos-Zapatero, Katherine K Ortell, Ralph Tanios, Mina Haghighiabyaneh, Joshua Axelrod, John W DeStefano, Isabelle Tancioni, David D Schlaepfer, Olivier Harismendy, Albert R La Spada, Dwayne G Stupack
Publikováno v:
PLoS Genetics, Vol 16, Iss 1, p e1008558 (2020)
Autophagy, particularly with BECN1, has paradoxically been highlighted as tumor promoting in Ras-driven cancers, but potentially tumor suppressing in breast and ovarian cancers. However, studying the specific role of BECN1 at the genetic level is com
Externí odkaz:
https://doaj.org/article/f42e584000f74e659bc9e24835d7c355
Autor:
Smita Krishnaswamy, Jahangir Sufi, Alexander Tong, Daniel Hochhauser, Petra Vlckova, Callum Baird Nattress, Christopher Tape, Maria Ramos Zapatero, Xiao Qin, Ferran Cardoso Rodriguez
Patient-derived organoids (PDOs) can model personalized therapy responses, however current screening technologies cannot reveal drug response mechanisms or study how tumor microenvironment cells alter therapeutic performance. To address this, we deve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87d11527e867065290abc848d874747b
https://doi.org/10.1101/2022.10.19.512668
https://doi.org/10.1101/2022.10.19.512668
Publikováno v:
Maria Ramos Zapatero
Understanding the dynamics and reactions of cells from population snapshots is a major challenge in single-cell transcriptomics. Here, we present Geodesic Sinkhorn, a method for interpolating populations along a data manifold that leverages existing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53919aa80c90b6dab04ec495b1390163
Autor:
Chandni Patel, Dwayne G. Stupack, Katherine K. Ortell, David D. Schlaepfer, Christian M. Jones, Isabelle Tancioni, Ralph Tanios, Olivier Harismendy, Jaidev Bapat, Mina Haghighiabyaneh, Albert R. La Spada, Maria Ramos-Zapatero, John W. DeStefano, Joe R. Delaney, Joshua Axelrod
Publikováno v:
PLoS Genetics, Vol 16, Iss 1, p e1008558 (2020)
PLoS genetics, vol 16, iss 1
PLoS Genetics
PLoS genetics, vol 16, iss 1
PLoS Genetics
Autophagy, particularly with BECN1, has paradoxically been highlighted as tumor promoting in Ras-driven cancers, but potentially tumor suppressing in breast and ovarian cancers. However, studying the specific role of BECN1 at the genetic level is com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79f3736fd27c04b839563ed85ad58939
https://doaj.org/article/f42e584000f74e659bc9e24835d7c355
https://doaj.org/article/f42e584000f74e659bc9e24835d7c355
Autor:
Chenchen Niu, Luke C. Bartelt, Toby Chen, Emily N. Griffin, Albert R. La Spada, Pawel M. Switonski, Maria Ramos-Zapatero, Joseph R. Delaney, Jaidev Bapat, Akshay Alaghatta, Nathanael J. Spann, Bryce L. Sopher
Publikováno v:
Cell reports
SUMMARY A common mechanism in inherited ataxia is a vulnerability of DNA damage. Spinocerebellar ataxia type 7 (SCA7) is a CAG-polyglutamine-repeat disorder characterized by cerebellar and retinal degeneration. Polyglutamine-expanded ataxin-7 protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e8d7df3cc6e7d36d0cf394dcc9cc33a
https://doi.org/10.1016/j.celrep.2021.110062
https://doi.org/10.1016/j.celrep.2021.110062