Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Maria R. D'Orsogna"'
Publikováno v:
Frontiers in Systems Biology, Vol 3 (2023)
Hematopoiesis has been studied via stem cell labeling using barcodes, viral integration sites (VISs), or in situ methods. Subsequent proliferation and differentiation preserve the tag identity, thus defining a clone of mature cells across multiple ce
Externí odkaz:
https://doaj.org/article/a8265ca37027489a9de972e9bae799fe
Publikováno v:
PLOS Global Public Health, Vol 3, Iss 3 (2023)
We examine trends in drug overdose deaths by race, gender, and geography in the United States during the period 2013–2020. Race and gender specific crude rates were extracted from the final National Vital Statistics System multiple cause-of-death m
Externí odkaz:
https://doaj.org/article/1f65bd4b3f024aafaa940056c9a94e48
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 664-690 (2021)
The hypothalamus–pituitary–adrenal (HPA) axis is a key neuroendocrine system implicated in stress response, major depression disorder, and post-traumatic stress disorder. We present a new, compact dynamical systems model for the response of the H
Externí odkaz:
https://doaj.org/article/0d408abcbd304e54ae3d66888131e83b
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
The specificity of T cells is that each T cell has only one T cell receptor (TCR). A T cell clone represents a collection of T cells with the same TCR sequence. Thus, the number of different T cell clones in an organism reflects the number of differe
Externí odkaz:
https://doaj.org/article/1c0e5efdeb4f400b971717fc9cb8f2c1
Publikováno v:
Computational Psychiatry, Vol 2, Pp 28-49 (2018)
We use a dynamical systems model of the hypothalamic–pituitary–adrenal (HPA) axis to understand the mechanisms underlying clinical protocols used to probe patient stress response. Specifically, we address dexamethasone (DEX) and ACTH challenge te
Externí odkaz:
https://doaj.org/article/3f09b0300eb04b96839350b2330b652f
Autor:
Tracy L. Stepien, Cole Zmurchok, James B. Hengenius, Rocío Marilyn Caja Rivera, Maria R. D’Orsogna, Alan E. Lindsay
Publikováno v:
Applied Sciences, Vol 10, Iss 18, p 6543 (2020)
Male and female moths communicate in complex ways to search for and to select a mate. In a process termed calling, females emit small quantities of pheromones, generating plumes that spread in the environment. Males detect the plume through their ant
Externí odkaz:
https://doaj.org/article/9c3ccb2630734bce8da7b4d9d10114ce
Publikováno v:
Royal Society Open Science, Vol 4, Iss 8 (2017)
We model radicalization in a society consisting of two competing religious, ethnic or political groups. Each of the ‘sects’ is divided into moderate and radical factions, with intra-group transitions occurring either spontaneously or through indo
Externí odkaz:
https://doaj.org/article/6f3c056209fe44308fe2831ee2df8506
Publikováno v:
ArXiv
Drug overdose deaths continue to increase in the United States for all major drug categories. Over the past two decades the total number of overdose fatalities has increased more than five-fold; since 2013 the surge in overdose rates is primarily dri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d8d890fb1664533b106524e9b5df72d
Autor:
Tom Chou, Maria R. D’Orsogna
Publikováno v:
Chaos
Substances of abuse are known to activate and disrupt neuronal circuits in the brain reward system. We propose a simple and easily interpretable dynamical systems model to describe the neurobiology of drug addiction that incorporates the psychiatric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d3bfff466cbb658df6a669ec3f3c523
http://arxiv.org/abs/2205.10704
http://arxiv.org/abs/2205.10704
Publikováno v:
medRxiv
article-version (status) pre
article-version (number) 2
Philosophical transactions. Series A, Mathematical, physical, and engineering sciences
article-version (status) pre
article-version (number) 2
Philosophical transactions. Series A, Mathematical, physical, and engineering sciences
We develop a statistical model for the testing of disease prevalence in a population. The model assumes a binary test result, positive or negative, but allows for biases in sample selection and both type I (false positive) and type II (false negative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8570261f85d0cf5441e699ad35791fc
https://doi.org/10.1101/2021.05.22.21257643
https://doi.org/10.1101/2021.05.22.21257643