Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Maria Quanz"'
Autor:
Anders Friberg, Hartmut Rehwinkel, Duy Nguyen, Vera Pütter, Maria Quanz, Jörg Weiske, Uwe Eberspächer, Iring Heisler, Gernot Langer
Publikováno v:
ACS Omega, Vol 5, Iss 22, Pp 13034-13041 (2020)
Externí odkaz:
https://doaj.org/article/b464774c28454d519fbffbf316422343
Autor:
Julian Biau, Flavien Devun, Wael Jdey, Ewa Kotula, Maria Quanz, Emmanuel Chautard, Mano Sayarath, Jian-Sheng Sun, Pierre Verrelle, Marie Dutreix
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 16, Iss 10, Pp 835-844 (2014)
Melanomas are highly radioresistant tumors, mainly due to efficient DNA double-strand break (DSB) repair. Dbait (which stands for DNA strand break bait) molecules mimic DSBs and trap DNA repair proteins, thereby inhibiting repair of DNA damage induce
Externí odkaz:
https://doaj.org/article/6aaf0bf67d824c9f9c89fb56d11b2ed9
Autor:
Ewa Kotula, Wolfgang Faigle, Nathalie Berthault, Florent Dingli, Damarys Loew, Jian-Sheng Sun, Marie Dutreix, Maria Quanz
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80313 (2013)
The DNA-dependent protein kinase (DNA-PK) may function as a key signaling kinase in various cellular pathways other than DNA repair. Using a two-dimensional gel electrophoresis approach and stable DNA double-strand break-mimicking molecules (Dbait32H
Externí odkaz:
https://doaj.org/article/151fd22635654c60a748b53d06294f83
Autor:
Maria Quanz, Danielle Chassoux, Nathalie Berthault, Céline Agrario, Jian-Sheng Sun, Marie Dutreix
Publikováno v:
PLoS ONE, Vol 4, Iss 7, p e6298 (2009)
Cellular response to DNA damage involves the coordinated activation of cell cycle checkpoints and DNA repair. The early steps of DNA damage recognition and signaling in mammalian cells are not yet fully understood. To investigate the regulation of th
Externí odkaz:
https://doaj.org/article/5f298f5c31644c45a7075a9c1b1cfd9c
Autor:
Andrea Hägebarth, Marcus Bauser, Holger Siebeneicher, Atanas Kamburov, Ralf Lesche, Claudia Merz, Joern Toedling, Carmen Richter, Roland Neuhaus, Luisella Toschi, Ashley Eheim, Wolfgang Schwede, Andreas Schlicker, Sylvia Grünewald, Charlotte Kopitz, Eckhard Bender, Maria Quanz
The lactate transporter SLC16A1/monocarboxylate transporter 1 (MCT1) plays a central role in tumor cell energy homeostasis. In a cell-based screen, we identified a novel class of MCT1 inhibitors, including BAY-8002, which potently suppress bidirectio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ecc176275426db1e8e7d752f623ce531
https://doi.org/10.1158/1535-7163.c.6537978.v1
https://doi.org/10.1158/1535-7163.c.6537978.v1
Autor:
Andrea Hägebarth, Marcus Bauser, Holger Siebeneicher, Atanas Kamburov, Ralf Lesche, Claudia Merz, Joern Toedling, Carmen Richter, Roland Neuhaus, Luisella Toschi, Ashley Eheim, Wolfgang Schwede, Andreas Schlicker, Sylvia Grünewald, Charlotte Kopitz, Eckhard Bender, Maria Quanz
Supplementary Methods: Synthesis and characterization of BAY-8002; Tritium labeling of AZD3965 and BAY-8002; MCT1 and MCT4 14C-lactate uptake measurements in the X. laevis oocytes expression System
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b9c449390e8d6d58b8fd14c10da3442
https://doi.org/10.1158/1535-7163.22505181
https://doi.org/10.1158/1535-7163.22505181
Autor:
Andrea Hägebarth, Marcus Bauser, Holger Siebeneicher, Atanas Kamburov, Ralf Lesche, Claudia Merz, Joern Toedling, Carmen Richter, Roland Neuhaus, Luisella Toschi, Ashley Eheim, Wolfgang Schwede, Andreas Schlicker, Sylvia Grünewald, Charlotte Kopitz, Eckhard Bender, Maria Quanz
Supplemental Table S1: Selectivity profile of BAY-8002. Supplemental Table S2: Summary table of functional and proliferation IC50 data for BAY-8002 and AZD3965. Supplemental Table S3: Responses to BAY-8002 and AZD3965 of cell lines with acquired resi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d4b47918c194f9c7b520dda50e82cba
https://doi.org/10.1158/1535-7163.22505184.v1
https://doi.org/10.1158/1535-7163.22505184.v1
Autor:
Andrea Hägebarth, Marcus Bauser, Holger Siebeneicher, Atanas Kamburov, Ralf Lesche, Claudia Merz, Joern Toedling, Carmen Richter, Roland Neuhaus, Luisella Toschi, Ashley Eheim, Wolfgang Schwede, Andreas Schlicker, Sylvia Grünewald, Charlotte Kopitz, Eckhard Bender, Maria Quanz
Supplemental Figure S1: A, SLC16A1 (MCT1), SLC16A7 (MCT2), SLC16A8 (MCT3) and SLC16A3 (MCT4) mRNA expression levels and Effects of BAY-8002 on lactate Export and ECAR. Supplemental Figure S2: Binding affinity of the two MCT1 inhibitors BAY-8002 and A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13f37e408a23840755a8e7e27d10ad6b
https://doi.org/10.1158/1535-7163.22505187
https://doi.org/10.1158/1535-7163.22505187
Autor:
Marie Dutreix, Jian-Sheng Sun, Lionel Larue, Jean-Marc Cosset, Xavier Sastre-Garau, Jean-Luc Coll, Véronique Josserand, Christophe Alberti, Céline Agrario, Aurélie Herbette, Maryline Roy, Christophe Roulin, Nathalie Berthault, Maria Quanz
Supplementary Data from Small-Molecule Drugs Mimicking DNA Damage: A New Strategy for Sensitizing Tumors to Radiotherapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d30cacd5078a6b900c2daef87a8e199f
https://doi.org/10.1158/1078-0432.22440753
https://doi.org/10.1158/1078-0432.22440753
Autor:
Charlotte Kopitz, Marcus Bauser, Roland Neuhaus, Sylvia Grünewald, Claudia Merz, Joern Toedling, Atanas Kamburov, Ashley Eheim, Eckhard Bender, Wolfgang Schwede, Holger Siebeneicher, Carmen Richter, Maria Quanz, Ralf Lesche, Andreas Schlicker, Andrea Hägebarth, Luisella Toschi
Publikováno v:
Molecular Cancer Therapeutics. 17:2285-2296
The lactate transporter SLC16A1/monocarboxylate transporter 1 (MCT1) plays a central role in tumor cell energy homeostasis. In a cell-based screen, we identified a novel class of MCT1 inhibitors, including BAY-8002, which potently suppress bidirectio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a02e5acad41f278b696aad948328f3c2
https://doi.org/10.1158/1535-7163.mct-17-1253
https://doi.org/10.1158/1535-7163.mct-17-1253